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prfC from Actinobacillus pleuropneumoniae L20

Victor ID 4086
Gene Name prfC from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4850473
NCBI Protein GI 126207518
Locus Tag APL_0030
Protein Accession YP_001052743.1
Other Database IDs UniProtKB-ID: RF3_ACTP2
UniRef100: UniRef100_A3MYA2
UniRef90: UniRef90_Q65SF0
UniRef50: UniRef50_Q2LWC5
UniParc: UPI0000397923
EMBL: CP000569
EMBL-CDS: ABN73138.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0030
eggNOG: COG4108
HOGENOM: HBG285678
OMA: LQFEVVQ
ProtClustDB: PRK00741
BioCyc: APLE416269:APL_0030-MONOMER
Taxonomy ID 416269
Gene Starting Position 35600
Gene Ending Position 37180
Gene Strand (Orientation) -
Protein Name peptide chain release factor 3
DNA Sequence 
>gi|126207488:35600-37180 Actinobacillus pleuropneumoniae L20, complete genome
ATTAATGTTCGCGTGTTTTAAAGAAGTTTATGTCGGGATAACGCTCTTGCGCCAGATTTAAGTTCACCAT
AGTCGGTGCGATATAAGTTAAGTTATCGCCGCCGTCTAATGCGAGGTTTTGTTCGTTTTTGCGTTTAAAT
TCTTCAAATTTCTTCGCATCACCGCACTCAACCCAACGAGCGGTTGCAACGTTTACCGCTTCGTAAATCG
CTTCCACGTTATATTCGGTTTTCAGACGGGAAACCACCACGTCAAACTGAAGCACACCGACCGCACCTAC
AATCAAGTCATTGTTCATTAACGGACGGAACACCTGTACAGCACCTTCTTCCGAAAGTTGAACTAAGCCT
TTCAGTAATTGTTTTTGCTTAAGTGGGTCTTTCAAGCGAATACGACGGAACAGTTCCGGTGCAAAGTTCG
GAATACCGGTAAATTTCATCACTTCACCTTGAGTGAAGGTGTCGCCGATTTGGATTGTGCCGTGGTTATG
TAAACCGATAATATCGCCGGCGTAAGCTTCTTCAGCATGTGCACGATCACCCGCCATAAAGGTTAAGGCA
TCGGAAATCACGACATCTTTGCCGATACGTACGTGTTTGAGCTTCATACCTTTTTCGTATTTGCCTGAAA
CAACGCGCATAAATGCCACTCGGTCACGGTGTTTCGGGTCCATATTCGCTTGGATCTTAAACACGAAGCC
AGAGAATTTTTCCTCGCTTGATTCGACCGTACGTACATCGGTTTGACGTGCTTGCGGTTTTGGCGCCCAT
TCGGTTAAACCGTCTAGGAAATGATCCACACCGAAGTTACCTAATGCGGTACCGAAGAATACCGGTGTTA
GTTCGCCGTTGATAAAGGCTTCGTGATCAAATTCGTTTGATGCACCTTGTACAAGTTCTAATTCTTCACG
TAACTGGTTAGCTAAATCATCACCGACCGCAGCATCAAGTTCCGGGCTGCTCAAGCCTTTTACGATACGT
ACTTCTTGAATGGTTGAACCTTGACCGGATTGATAAAGATAGGTTTCGTCTTTTGCAATATGATAGACGC
CTTTAAATAATTTACCGCAACCAATCGGCCAAGTAATCGGCGCACAACGGATTTTTAGGACGCTTTCAAC
TTCATCTAGTAACTCCATCGGATCACGGATATCACGGTCGAGTTTGTTCATAAAAGTTAAGATCGGCGTA
TCACGCAGACGAGTCACTTCTATTAATTTAATTGTACGTTCCTCAACACCTTTTGCACTGTCGATAACCA
TTAAGCAGCTATCTACCGCAGTCAATGTGCGGTAAGTATCTTCGGAGAAGTCTTCGTGTCCGGGGGTATC
CAATAAATTAACTAAACAATTATTGTAAGGAAATTGCATGACGGACGTTGTAATAGAAATACCGCGTTGT
TTTTCCATTTCCATCCAGTCGGATTTGGCGTGTGCGCTAGAGCCTTTTCCTTTCACTGAACCGGCGGTTT
GGATTGCATTTCCGTAAAGTAAAACTTTTTCGGTTATGGTGGTTTTACCCGCATCGGGGTGAGAAATAAT
CGCAAAGGTACGACGTTTATTGACTTCTTGTGGATATGACA
Protein Sequence 
>gi|126207518|ref|YP_001052743.1| peptide chain release factor 3 [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSYPQEVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSSAHAKSDWMEMEKQRGISITTSVMQFPYNNCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLIEVTRLRDTPILTFMNKLDRDIRDPMELLDEVESVLKIRCAPITWPIGCGKLFKGVYHIAKDETYLYQSGQGSTIQEVRIVKGLSSPELDAAVGDDLANQLREELELVQGASNEFDHEAFINGELTPVFFGTALGNFGVDHFLDGLTEWAPKPQARQTDVRTVESSEEKFSGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLKHVRIGKDVVISDALTFMAGDRAHAEEAYAGDIIGLHNHGTIQIGDTFTQGEVMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLMNNDLIVGAVGVLQFDVVVSRLKTEYNVEAIYEAVNVATARWVECGDAKKFEEFKRKNEQNLALDGGDNLTYIAPTMVNLNLAQERYPDINFFKTREH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: prfC mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG4108J, under J: Translation, ribosomal structure and biogenesis
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].