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pnp from Actinobacillus pleuropneumoniae L20

Victor ID 4050
Gene Name pnp from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849054
NCBI Protein GI 126208059
Locus Tag APL_0577
Protein Accession YP_001053284.1
Other Database IDs UniProtKB-ID: PNP_ACTP2
UniRef100: UniRef100_A3MZU3
UniRef90: UniRef90_A3MZU3
UniRef50: UniRef50_A1UU54
UniParc: UPI0000397B14
EMBL: CP000569
EMBL-CDS: ABN73679.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0577
eggNOG: COG1185
HOGENOM: HBG382411
OMA: YGETVVL
ProtClustDB: PRK11824
BioCyc: APLE416269:APL_0577-MONOMER
Taxonomy ID 416269
Gene Starting Position 650505
Gene Ending Position 652652
Gene Strand (Orientation) -
Protein Name polynucleotide phosphorylase/polyadenylase
DNA Sequence 
>gi|126207488:650505-652652 Actinobacillus pleuropneumoniae L20, complete genome
TTTAAATCTCAGCTTGTTGTTCTGACGAAACTTCCGCTTCTTCAGTTACATTTTCGGCAACAGGGGTATC
GTTATTAAGATCTTTCATAGTTAAACGGATACGGTTTTGACGATCGATTTCAACTACTTTCACAGTCACT
TCTTGACCTACGGATAAGTAATCCGCAACGCGTTCGACACGCTCATTCGTGATTTGCGAAATATGTACTA
AACCTTCTTTACCACCTAAGATAGAAACGAACGCACCGAAGTCCACAACGCGAGTTACTTTACCTTTGTA
GATCGCGTTCACTTCAACTTCAGCCACGATATCTTCGATACGAGCCATTACCGCTTTCGCCGCATTATTA
TCGGTTGCAGCGATTTTTACGGTACCGTCGTCATCAATATCAATCGAAGTACCGGTTTCTTCGGTTAATG
CACGAATTACCGCACCACCTTTACCGATAACGTCTTTGATTTTCTTCGGATCGATTTTCATCGTATGAAT
ACGAGGCGCAAAATCGGAAATATCGGCACGAGGTGCAGGAATCGCTTGTTCCATCACGCTTAAGATGTGC
ATACGCGCACCTTTCGCTTGATTTAATGCGATTTGCATAATTTCCGGCGTGATACCTTCGATTTTAATAT
CCATTTGAAGTGCGGTTACACCTTCACGCGTACCGGCTACTTTGAAGTCCATATCGCCTAAATGGTCTTC
GTCACCTAAGATGTCTGAAAGCACCACAAATTTTTCTTCTTCTTTCACTAAGCCCATTGCGATACCCGCA
ACCGCCGCTTTAATCGGTACGCCTGCGTCCATTAACGCTAAAGATGCGCCGCATACGGAAGCCATTGAAG
AAGAACCGTTTGATTCGGTAATTTCAGATACTACGCGCACTACATACGGGAATTCTTCCGCAGTCGGCAT
TACCGCTAATACACCGCGTTTCGCTAAACGACCGTGGCCGATTTCACGACGTTTCGGCGAACCGATACGA
CCCGTTTCACCGACAGAGTACGGAGGGAAGTTATAGTGGAATAAGAAACGGTCTGATTTCTCGCCGGTTA
ATTCGTCAATAATTTGTGCATCGCGCTCAGTACCTAAGGTTGCAACCGCTAATGCTTGTGTTTCACCGCG
AGTAAAGATTGCAGAACCGTGCGTACGAGGTAATACGCCGGTGCAAATGTCTAATGCACGAACCGTATCT
ACCGTACGACCGTCAATACGCGGTTCGCCGGCAATAATACGACCACGCACGATAGAACTTTCTAATGCGG
TAATAATATCGATAATCGCACCTTCCGAAACGGTTTCGTCTTGTGCGGTTAATTGTGCGATAACATCCGC
TTTAATTGCATCGATTTGTTCGTAACGCGCTTGTTTTTCAGTGATACGATACGCATCACCGATACGCGCT
TCCGCTAACGCTTTAACTTGGTTGATTAATGCGGTATTCGGTTCCGGCGCAACCCAATCCCAACGCGGTT
TACCCGCTTCTTTTACGAATTCTTTAATATTTTCAATTACAACTTGTTGTTGCTGATGACCGAATACGAC
TGCGGATAACATTTGTTCTTCAGAAAGAATATCCGCTTCCGATTCAACCATTAATACCGCTTTATCCGTC
CCTGCTACTACAAGGTCTAAGCGGCTGATTTTTTGTTCTGAAGTGGTCGGGTTTAATACGAATTGATCAT
TGATAAAACCGACACGCGCCGCACCGATAGGACCGTTGAACGGTACGCCTGATAATGAAAGCGCCGCTGA
AGCACCGATCATCGCCACTAAATCCGGGCTGATTTGCGGGTTCACCGAAACAACCGTAGCAATCACTTGA
ATTTCGTTAAAGAAACCTTCCGGGAAAAGCGGGCGCACAGGACGGTCGATTAAACGAGCGATTAATGTTT
CGCCTTCTGACGGACGACCTTCACGTTTGAAGAAACCGCCGGGAATACGACCGGCTGCATAAGTACGCTC
TTGATAATCTACCGTTAATGGGAAGAAATCTTGACCTTCTTTAACCTCTTTTTTAGCCACAACGGTGACG
AATACGGTGGTATCGTCCATGCTTGCCATAACGGCCGCCGTTGCTTGACGTGCGATAGCACCTGTTTCTA
ACGTTACGGTATGCTGACCGTATTTAAATTGCTTAACAATTGGATTCA
Protein Sequence 
>gi|126208059|ref|YP_001053284.1| polynucleotide phosphorylase/polyadenylase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKEVKEGQDFFPLTVDYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPVRPLFPEGFFNEIQVIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFINDQFVLNPTTSEQKISRLDLVVAGTDKAVLMVESEADILSEEQMLSAVVFGHQQQQVVIENIKEFVKEAGKPRWDWVAPEPNTALINQVKALAEARIGDAYRITEKQARYEQIDAIKADVIAQLTAQDETVSEGAIIDIITALESSIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGEKSDRFLFHYNFPPYSVGETGRIGSPKRREIGHGRLAKRGVLAVMPTAEEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKGARMHILSVMEQAIPAPRADISDFAPRIHTMKIDPKKIKDVIGKGGAVIRALTEETGTSIDIDDDGTVKIAATDNNAAKAVMARIEDIVAEVEVNAIYKGKVTRVVDFGAFVSILGGKEGLVHISQITNERVERVADYLSVGQEVTVKVVEIDRQNRIRLTMKDLNNDTPVAENVTEEAEVSSEQQAEI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pnp mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG1185J, under J: Translation, ribosomal structure and biogenesis
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].