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hemE from Actinobacillus pleuropneumoniae serovar 7 str. AP76

Victor ID 4177
Gene Name hemE from Actinobacillus pleuropneumoniae serovar 7 str. AP76
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 7 str. AP76
NCBI Gene ID 6397393
NCBI Protein GI 190149381
Locus Tag APP7_0112
Protein Accession YP_001967906.1
Other Database IDs UniProtKB-ID: DCUP_ACTP7
UniRef100: UniRef100_A3MYI4
UniRef90: UniRef90_A3MYI4
UniRef50: UniRef50_Q1QA45
UniParc: UPI0000F28403
EMBL: CP001091
EMBL-CDS: ACE60764.1
RefSeq_NT: NC_010939.1
GenomeReviews: CP001091_GR
KEGG: apa:APP7_0112
HOGENOM: HBG628392
OMA: AVQLFDS
ProtClustDB: PRK00115
Taxonomy ID 537457
Gene Starting Position 135926
Gene Ending Position 136990
Gene Strand (Orientation) +
Protein Name uroporphyrinogen decarboxylase
DNA Sequence 
>gi|190149269:135926-136990 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome
TATGAACCAATTAAAAAATGATCGTTACTTAAAAGCGTTACTACGTGAACCAGTTGATATGACACCGGTA
TGGATGATGCGTCAAGCGGGGCGTTATCTACCGGAATATAAAGCGACACGTGCGGAAGCCGGCGATTTTA
TGGCTTTATGTCGCAATGCAGATTTAGCTTGTGAAGTGACGTTACAGCCGCTACGCCGCTATGCATTGGA
TGCGGCGATTTTATTCTCCGATATTTTAACCGTTCCGGATGCAATGGGCTTAGGTTTAAGTTTCGGTGCG
GGTGAAGGGCCTAAATTTGCTCGCCCGATTGAAAATAAAGCGCAGGTGGACAACTTACCGATTCCGGATC
CGGAAAGCGAATTACAATATGTGATGAATGCGGTACGTACTATTCGCCGTGAATTAAAAGGCGAAGTGCC
GTTAATCGGTTTTTCAGGTAGCCCGTGGACATTGGCGACTTATATGGTGGAAGGCGGCTCAAGCAAAGCG
TTCACCAAAATTAAAAAAATGATGTATGCCGATCCGAAAATTTTACACGCATTATTAGATAAATTAGCCG
ATAGCGTGATCTTATATCTGAATGCACAAATTAAAGCCGGCGCGCAAGCGGTGATGGTGTTCGATACTTG
GGGCGGCGTGTTGGCGCATAACGAATATAAAGAGTTCTCGCTACGTTATATGCACAAAATCGTGGACGGT
TTAATTCGTGAAAACGAAGGCAGAAAAGTGCCGGTAACTTTATTTACCAAAGGCGGCGGTTTATGGTTGG
AAGCGATTGCGGAAACCGGTTGTGATGCGGTCGGTTTAGACTGGACGGTCGATATTGCCGATGCGCGTCG
TCGTGTCGGACATAAAGTGGCGTTACAAGGCAATATGGATCCGAGCGTATTGTATGCGCAGCCGGAGCGT
ATCGAGCTGGAAGTGAAACAAATCTTAGCCGGTTTCGGTCAAGGCTCCGGTCATGTGTTCAACCTCGGAC
ACGGTATTCATCAAGACGTGCCGGAACAAAGCCCGAAAGTGTTTGTTGATGCGGTCCACGAGTATTCAAA
ACAATACCATAAGTA
Protein Sequence 
>gi|190149381|ref|YP_001967906.1| uroporphyrinogen decarboxylase [Actinobacillus pleuropneumoniae serovar 7 str. AP76] MNQLKNDRYLKALLREPVDMTPVWMMRQAGRYLPEYKATRAEAGDFMALCRNADLACEVTLQPLRRYALDAAILFSDILTVPDAMGLGLSFGAGEGPKFARPIENKAQVDNLPIPDPESELQYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKMMYADPKILHALLDKLADSVILYLNAQIKAGAQAVMVFDTWGGVLAHNEYKEFSLRYMHKIVDGLIRENEGRKVPVTLFTKGGGLWLEAIAETGCDAVGLDWTVDIADARRRVGHKVALQGNMDPSVLYAQPERIELEVKQILAGFGQGSGHVFNLGHGIHQDVPEQSPKVFVDAVHEYSKQYHK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hemE mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0407H, under H: Coenzyme transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].