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guaA from Actinobacillus pleuropneumoniae serovar 7 str. AP76

Victor ID 4174
Gene Name guaA from Actinobacillus pleuropneumoniae serovar 7 str. AP76
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 7 str. AP76
NCBI Gene ID 6396394
NCBI Protein GI 190149906
Locus Tag APP7_0637
Protein Accession YP_001968431.1
Other Database IDs UniProtKB-ID: GUAA_ACTP7
UniRef100: UniRef100_B3H120
UniRef90: UniRef90_A3MZV8
UniRef50: UniRef50_Q3JR65
UniParc: UPI0001761871
EMBL: CP001091
EMBL-CDS: ACE61289.1
RefSeq_NT: NC_010939.1
GenomeReviews: CP001091_GR
KEGG: apa:APP7_0637
HOGENOM: HBG391775
OMA: MKLVEPL
ProtClustDB: PRK00074
Taxonomy ID 537457
Gene Starting Position 708272
Gene Ending Position 709843
Gene Strand (Orientation) -
Protein Name GMP synthase
DNA Sequence 
>gi|190149269:708272-709843 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome
TTTATTCCCACTCAATCGTTGCAGGAGGTTTGCCTGAAACGTCATACACTACGCGAGAAATGCCGTTTAC
TTCATTGATAATACGGTTTGAGATTTTACCAAGTAAATCGTATGGTAAATGCGCCCAATGTGCGGTCATA
AAGTCGATAGTTTCCACCGCACGGAGTGAAACAACCCAGTCGTATTTACGACCGTCGCCCATTACACCTA
CCGATTTCACAGGAAGGAATACGGTAAACGCTTGGCTTACTTTGTAATACCAATCCGCTTTGTAGAGCTC
TTCGATAAAGATTGCATCTGCTTTACGGAGTAAATCACAGTATTCTTTCTTGATTTCACCTAATACTCGC
ACACCCAAACCCGGACCCGGGAATGGGTGGCGATTAAGCATTTCTGCCGGTAAGCCAAGAGCTAAACCGA
TTTTACGCACTTCATCTTTAAATAATTCACGTAACGGCTCAACTAAACCGAGTTTCATATAATCCGGTAA
GCCGCCTACGTTATGGTGAGATTTAATCACGTGTGCTTTACCGGTTTTGCTCGCAGCGGATTCGATAACG
TCAGGGTAGATTGTGCCTTGTGCTAACCATTTTACTGAAGTGAGTTTTTTCGACTCATCATCGAATACAT
CGACAAACACTTTACCGATGGTTTTACGTTTTGCTTCCGGTTCATCAATACCTTTTAACGCATCTAAGAA
ACGGTCTTCGGCATTTACACGAATGATATTTAAACCGAATTTATCGCCGAACATTTCCATCACTTGATCG
CCTTCGTTTAAACGAAGTAAACCGTTATCCACGAATACGCAGTGTAAGTTTTTGCCGATTGCACGATGTA
GAAGAAGTGCGGTTACTGATGAATCCACGCCGCCTGATAAACCTAAAATGACTTCGTCATCGCCTACTTG
CTCTTTAATACGAGCGACAGCGTCTTCGATAATATTTTCTGCCGTCCATTTACATTCGCAACCACAAATG
CCTACTACGAAGTTAGTTAATAACTCTAAACCGCTTTTCGTATGAGTTACTTCCGGGTGGAATTGCACAC
CATAGAAACGACGGCTTTCGTCTGACATTGCTGCAATCGGGCAAGTTGGCGTTATACCTGTTACTTGGAA
ACCTTGCGCTAAACGAGTTACTTTATCGCCGTGGCTCATCCAAACGTCTAATTTCGGCTCGGAAGCGGTC
AAATTATCGTTTAATTTTGCAAATAACGCATCGGTCGCTTGTAAATCAACGGAAGCATAACCGAATTCAC
GATGATCAGAAGTTTCAGTTAAACCGCCTAATTGCATCGCCATGGTTTGCATACCATAGCAAATACCAAG
TACTGGCACGCCTGCGTTAAATACGTACTCCTGCGCACGAGGGCTGTTTTCTTCAGTGGTACTTTCAGGA
CCACCTGAAAGAATGATCCCGGTCGGGTTAAATTCACGGATTTGTTCTTCGGTGACATCCCACGCCCAAA
GCTCGCAATAAACCCCAATCTCACGCACACGACGTGCGATTAATTGCGTGTATTGTGAACCGAAGTCCAA
AATTAAAATTTTATGATTGTGAATGTTGGTCA
Protein Sequence 
>gi|190149906|ref|YP_001968431.1| GMP synthase [Actinobacillus pleuropneumoniae serovar 7 str. AP76] MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAQEYVFNAGVPVLGICYGMQTMAMQLGGLTETSDHREFGYASVDLQATDALFAKLNDNLTASEPKLDVWMSHGDKVTRLAQGFQVTGITPTCPIAAMSDESRRFYGVQFHPEVTHTKSGLELLTNFVVGICGCECKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSVTALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPEAKRKTIGKVFVDVFDDESKKLTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHPFPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELYKADWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: guaA mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0519F, under F: Nucleotide transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].