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thrC from Actinobacillus pleuropneumoniae L20

Victor ID 4045
Gene Name thrC from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848887
NCBI Protein GI 126208963
Locus Tag APL_1499
Protein Accession YP_001054188.1
Other Database IDs UniProtKB-ID: A3N2E7_ACTP2
UniRef100: UniRef100_A3N2E7
UniRef90: UniRef90_A3N2E7
UniRef50: UniRef50_Q89AR5
UniParc: UPI0000397CAE
EMBL: CP000569
EMBL-CDS: ABN74583.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1499
eggNOG: COG0498
HOGENOM: HBG521025
OMA: VCYYFEA
ProtClustDB: PRK09225
BioCyc: APLE416269:APL_1499-MONOMER
Taxonomy ID 416269
Gene Starting Position 1714872
Gene Ending Position 1716152
Gene Strand (Orientation) +
Protein Name threonine synthase
DNA Sequence 
>gi|126207488:1714872-1716152 Actinobacillus pleuropneumoniae L20, complete genome
AATGAACTTATACAACATCAAACACCCAGAAGAACAAGTTAATTTCGCACAAGGCGTGCGCCAAGGTTTA
GGTAAGGATCAGGGGTTATTTTTCCCTGAAGTGTTACCGAAATTTGACGATATTGATGCGTTACTGGATT
TACCTTTGGTTGAACGCAGCCAAAAAATTTTGGCGGCACTTATCGGTAACGAACTTCCGCAAGAAACGGT
AAATGCCATGGTAAAAAATGCGTTTACTTTCCCTGCTCCATTAGCAAAAGTGAATGACTATATTTATGCA
CTTGAGCTGTTCCACGGCCCGACATTGGCATTTAAAGACTTCGGCGGTCGTTTTATGGCGCAAGCACTGG
CAAGCGTGCGTGGTGACGGCAAAATCACCATTTTAACCGCAACCTCAGGCGACACCGGTGCGGCGGTAGC
GCACGCATTTTATGGCTTAGAAAATATCAATGTAGTGATCCTTTACCCGAAAGGCAAAATCAGCCCGTTA
CAAGAAAAATTATTCTGTACCTTAGGCGGTAACATTCGTACCGTTGCGATTGAATCGGATTTTGACGCTT
GCCAAGTGTTAGTAAAACAAGCGTTTGACGATGCTGAATTACGTCAAGCGATCGGCTTAAACTCCGCAAA
CTCAATCAATATCAGCCGTTTATTAGCGCAAGTTTGTTATTACTTTGAAGCGGTAGCACAATTACCGAAA
GCAAAACGTTCTGATGTAGTGGTTTCAGTACCAAGCGGTAACTTCGGTAACTTAACCGCTGGTTTAATCG
CAAAAACCTTAGGTTTACCAATTAAACGTTTTATCGCATCAACCAATGCGAATGACACAGTGCCGCGTTA
TTTAAAATCAGGTAAATGGGAACCGAACGCAACGGTAGCAACGCTTTCAAACGCAATGGACGTAAGCCGC
CCGAACAACTGGCCTCGTGTGGAAGAATTATTTAAACGCAACGGTTGGGCGTTAAGCGATTTAGGTTCGG
CGGCATTAAACGATGCGGAAACCGAAGCGGCATTAAAAGCACAATATGCGGAAGGTTATTTATGCGAACC
GCACGGTGCAATCGCTTACCAAGCGTTAAAAGATCAGCTTCAAGCGGGCGAAACCGGTATTTTCCTCTGC
ACCGCTCACCCGGCAAAATTCAAAGAAAGCGTAGAACGTATTCTTAACATCGAATTACCACTACCGGAAG
CATTGGATAAACATAACAAAATGGAATTATTATCCGACACTATGCCGGCGGATTTCGCCAAATTACGTGA
GTATTTGTTAGCGGGTAACTA
Protein Sequence 
>gi|126208963|ref|YP_001054188.1| threonine synthase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MNLYNIKHPEEQVNFAQGVRQGLGKDQGLFFPEVLPKFDDIDALLDLPLVERSQKILAALIGNELPQETVNAMVKNAFTFPAPLAKVNDYIYALELFHGPTLAFKDFGGRFMAQALASVRGDGKITILTATSGDTGAAVAHAFYGLENINVVILYPKGKISPLQEKLFCTLGGNIRTVAIESDFDACQVLVKQAFDDAELRQAIGLNSANSINISRLLAQVCYYFEAVAQLPKAKRSDVVVSVPSGNFGNLTAGLIAKTLGLPIKRFIASTNANDTVPRYLKSGKWEPNATVATLSNAMDVSRPNNWPRVEELFKRNGWALSDLGSAALNDAETEAALKAQYAEGYLCEPHGAIAYQALKDQLQAGETGIFLCTAHPAKFKESVERILNIELPLPEALDKHNKMELLSDTMPADFAKLREYLLAGN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: thrC mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0498E, under E: Amino acid transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].