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apxIC

Victor ID 4066
Gene Name apxIC
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849898
NCBI Protein GI 126208909
Locus Tag APL_1445
Protein Accession YP_001054134.1
Other Database IDs UniProtKB-ID: A3N293_ACTP2
UniRef100: UniRef100_P55132
UniRef90: UniRef90_P55132
UniRef50: UniRef50_P09985
UniParc: UPI0000135294
EMBL: CP000569
EMBL-CDS: ABN74529.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1445
eggNOG: COG2994
HOGENOM: HBG296557
OMA: WALMDAD
ProtClustDB: CLSK862057
BioCyc: APLE416269:APL_1445-MONOMER
Taxonomy ID 416269
Gene Starting Position 1656004
Gene Ending Position 1656522
Gene Strand (Orientation) -
Protein Name RTX-I toxin-activating lysine-acyltransferase ApxIC
DNA Sequence 
>gi|126207488:1656004-1656522 Actinobacillus pleuropneumoniae L20, complete genome
CTTAGCTATTTACTAATGAAAATTTAAAATTTTGTTTATTTTTTAGCTCACTCATTAATTCAAAGTGATA
TTGTTGAAAAATTTTACTTGCCAGTTTCTTATCAATTTTTCCTCCATGAAATTCTGAAATTTTCCCTACT
CGAGAGTCCGGATCAACTCGAATAGCCCTAAACAGCTCATTCGGGAAGTTATCTCGCATATGTTTGTATA
ATGCGGCACTGTCTCCGAACGGTGCTATCCAATCTATAAACCATCGACGATCGCCGGAAGTCCAATCATC
CGCAACTAGCGAGGCAACATCATCAAGGTATTTAATTTCATTTTCCAAATTCAAATTTGCCCAGCTACAA
AATGCAATAGGAAAACCGTCACGCTTTAACAAAACATATTGATTACTCTCAATCGCAGGTAGCACATTAA
TTGCTAACAAAGAAAGCGGCCACTTTCGATGTAAAGGAGAACTTGCCCATAACCATGCCACCTCTCCTAA
AACCTCAAATCCATTAATTTTTTTACTCA
Protein Sequence 
>gi|126208909|ref|YP_001054134.1| RTX-I toxin-activating lysine-acyltransferase ApxIC [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSKKINGFEVLGEVAWLWASSPLHRKWPLSLLAINVLPAIESNQYVLLKRDGFPIAFCSWANLNLENEIKYLDDVASLVADDWTSGDRRWFIDWIAPFGDSAALYKHMRDNFPNELFRAIRVDPDSRVGKISEFHGGKIDKKLASKIFQQYHFELMSELKNKQNFKFSLVNS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: apxlC mutant is attenuated in mice (Xu et al., 2007).
COG COG2994O, under O: Posttranslational modification, protein turnover, chaperones
References
Xu et al., 2007: Xu FZ, Shi AH, Chen XL, Yang B, Wang JL. [Construction and immunogenicity of an attenuated mutant of Actinobacillus pleuropneumoniae by insertional inactivation of apxIC]. Wei sheng wu xue bao = Acta microbiologica Sinica. 2007; 47(5); 923-927. [PubMed: 18062275].