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hlyX from Actinobacillus pleuropneumoniae L20

Victor ID 4080
Gene Name hlyX from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4850318
NCBI Protein GI 126208136
Locus Tag APL_0656
Protein Accession YP_001053361.1
Other Database IDs UniProtKB-ID: A3N020_ACTP2
UniRef100: UniRef100_A3N020
UniRef90: UniRef90_A3N020
UniRef50: UniRef50_Q46158
UniParc: UPI00003978DF
EMBL: CP000569
EMBL-CDS: ABN73756.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0656
eggNOG: COG0664
HOGENOM: HBG753167
OMA: FSANQFR
ProtClustDB: PRK11161
BioCyc: APLE416269:APL_0656-MONOMER
Taxonomy ID 416269
Gene Starting Position 750741
Gene Ending Position 751508
Gene Strand (Orientation) +
Protein Name fumarate/nitrate reduction transcriptional regulator
DNA Sequence 
>gi|126207488:750741-751508 Actinobacillus pleuropneumoniae L20, complete genome
TATGAAAATTGTATCTGACGCTAAACATACAGGCCGAACGGCTTGCACTATTCATTGCCAGAATTGCAGT
ATTAGCCAACTTTGCTTACCTTTTACGTTGAGCGAACACGAATTAACTCAGCTTGACAATATTATCGAAC
GCAAAAAACCGGTTCAAAAATCTCAAATCATTTTCCAATCCGGCGATGAACTTCGTTCCATCTATGCGAT
TCGTTCAGGTACAATTAAAAGCTATACGATTAGCGAAAGCGGCGAAGAACAAATTACGGCGTTCCATTTA
CCCGGTGATCTGGTCGGATTTGATGCGATTATGAATATGAAACATGTCGGTTTCGCACAAGCGCTCGAAA
CGTCGATGATTTGCGAGATTCCATTTGATATTTTAGACGATCTCGCCGGCAAGATGCCTAAAATCCGTCA
TCAAATTATGCGTTTGATGAGTAATGAAATTAAAAGCGATCAAGAAATGATTTTATTACTTTCAAAAATG
AGTGCGGAAGAAAAGTTAGCGGCGTTTTTACATAATTTATCTCAACGTTATGCGGCACGCGGTTTTTCCG
CTCGTGAATTCCGTCTGACTATGACTCGCGGCGATATCGGCAACTATCTCGGTTTAACCATTGAAACTAT
CAGTCGTTTATTAGGACGTTTCCAGAAAAGCGGTATGATTACGGTACAAGGTAAATATATTACCATCAAT
CGTATGGACGAACTGACCGATATGGCGGGTGTAACACGTTCACAAATTCCGGTAATACAAACGGCATA
Protein Sequence 
>gi|126208136|ref|YP_001053361.1| fumarate/nitrate reduction transcriptional regulator [Actinobacillus pleuropneumoniae serovar 5b str. L20] MKIVSDAKHTGRTACTIHCQNCSISQLCLPFTLSEHELTQLDNIIERKKPVQKSQIIFQSGDELRSIYAIRSGTIKSYTISESGEEQITAFHLPGDLVGFDAIMNMKHVGFAQALETSMICEIPFDILDDLAGKMPKIRHQIMRLMSNEIKSDQEMILLLSKMSAEEKLAAFLHNLSQRYAARGFSAREFRLTMTRGDIGNYLGLTIETISRLLGRFQKSGMITVQGKYITINRMDELTDMAGVTRSQIPVIQTA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hlyX mutant is attenuated in pigs (Baltes et al., 2005).
COG COG0664T, under T: Signal transduction mechanisms
References
Baltes et al., 2005: Baltes N, N'diaye M, Jacobsen ID, Maas A, Buettner FF, Gerlach GF. Deletion of the anaerobic regulator HlyX causes reduced colonization and persistence of Actinobacillus pleuropneumoniae in the porcine respiratory tract. Infection and immunity. 2005; 73(8); 4614-4619. [PubMed: 16040973].