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tbpB

Victor ID 4081
Gene Name tbpB
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4850335
NCBI Protein GI 126209032
Locus Tag APL_1568
Genbank Accession CP000569
Protein Accession YP_001054257
Other Database IDs UniProtKB-ID: A3N2L6_ACTP2
UniRef100: UniRef100_A3N2L6
UniRef90: UniRef90_A3N2L6
UniRef50: UniRef50_A3N2L6
UniParc: UPI00000BCF93
EMBL: CP000569
EMBL-CDS: ABN74652.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1568
eggNOG: NOG11354
HOGENOM: HBG576376
OMA: GERTATD
ProtClustDB: CLSK965643
BioCyc: APLE416269:APL_1568-MONOMER
Taxonomy ID 416269
Gene Starting Position 1795908
Gene Ending Position 1797551
Gene Strand (Orientation) -
Protein Name transferrin-binding protein
Protein pI 6.35
Protein Weight 56138.93
Protein Length 547
DNA Sequence 
>gi|126207488:1795908-1797551 Actinobacillus pleuropneumoniae L20, complete genome
ATTATTTTTCTATTTGTCGTTTTGCACCAAAGACAGCGCCAACACTGCCATTGTCTGATTTATGATGGAA
TTGTCCGCCAAGTTCTCCAGCGGTTGGACCATAGAAGCCACCATTGACTTTTATATCACTAAATACCGCA
TTTCCGTGTTGGCTAGAGCCTGAATCTAACGCAAAGCCTGTATCTGTAGTGTTAGCTGTCCCAGTAAAGC
CGTTACCTTTAATATCTGCGTTGATCATAAAGACAGGTACTATGCCCCCTTTATCAAATAACTTGCCGCT
TACTTTTTTATCACCAAAATTAACATCAAATTCTGAGCGATAGCCCGATTCTCGATTATTATCCGCCTCA
GCTACCCAGTTCGTTCCTTTTGAAACGAGTGCATCCCAGGTTCCTACATATTTATAGTTTCCACCTACGG
GTATTTTATCTGTGGCAGTACGCTCACCTTGCAGGAATAAGCTATTATCTTTAGTTTGTTCGCCCTCTTT
TTGCCATAATTGACCAAATTTCATATATTCCAAATTACTACAGCAAGCTATGGCTACCATTGTCTTACCA
TTGATATCAACGGTTTTTCTATTTTTAAAATCTGCACCTGCTAGATCTATTTTCTGTCCATCAATAATTA
ACACATTAGCGTTGCCGAAATTGTTGAGTTCCGATGATTCAAAAGTAGTTAAATCAATTTTTGAGGCATC
AATGATCTTGACTGTTTCAAGAACGTCATTACCTCTTTTGCCAGAGAATACCGCAAAAAGAGATTTATCA
TGAGCTACAAATTTTCCTGCAAGTTCTTCTGATTTTGGACCATATAAGCCACCTTCAAGATGCTCAGAAT
CTTTACCTAATATCGGATCTGTTTTATCAGTAGCAGTCGCTTTTCCTCTAAAACGATTGCCACTAATGTT
AGCTTCAACGGTATAGCGTAATTTTTCTTGATTTTCTTTTGTTTTAGTAAGTAACTGACCATTCAATTTC
TTATTTGAAAAATCTATGTTGAACTTCGAGATATAAGTTCTTTCTTTTGCATCTGCAGAAGTAACTCCAA
CTCTTTGCCCTGCGCCATAGCCATTAAATTCAGGATTGTAATTTGGTCTTTTGGCATCTAGATCGGCATT
TGAGGTAAAGTCCCACTCTCCTTGATAAACGATAATATTGCCTTTAGGGAGCTCTTTGGAAGGATGAACT
CCTTTGTAGTAAACATATCCTTTATCTCTTAAACCATAATGATCAACATCAATCGTATATCCAGAACGAA
CAAAATTCATAGTGTTACTTCCAGATTTTGTTACTACCGACCCATAATTCTCGTTAGCGATTGTTCTTAA
TTTGTCCTCATTTGGAACGAGAGAGAGAGATTCATCAGTCACTGTATCAATTTCTGAAATTTCTGTTTTT
CTTACACTAGGTATATTGACTGGGATTTTTGTTACATATCCCAAAGCAGGTTCCATCAACTTATCTAACT
CTTCTTTTTTCCTTTTTTGTGTTTCTTCGTCGGTATAATTCACTTTTGTTTTTTCTGGTTCAACGGCTTT
ATTTGGTTGAACATCATCCAAATCAAAGCTACCTTTTCCACCAGAACAAGCTACAAGGAAAGTTGAGGTA
AGAGCTACTATATATAGGTCGGATTTAAAATGCA
Protein Sequence 
>gi|126209032|ref|YP_001054257.1| transferrin-binding protein [Actinobacillus pleuropneumoniae L20]
MHFKSDLYIVALTSTFLVACSGGKGSFDLDDVQPNKAVEPEKTKVNYTDEETQKRKKEELDKLMEPALGY
VTKIPVNIPSVRKTEISEIDTVTDESLSLVPNEDKLRTIANENYGSVVTKSGSNTMNFVRSGYTIDVDHY
GLRDKGYVYYKGVHPSKELPKGNIIVYQGEWDFTSNADLDAKRPNYNPEFNGYGAGQRVGVTSADAKERT
YISKFNIDFSNKKLNGQLLTKTKENQEKLRYTVEANISGNRFRGKATATDKTDPILGKDSEHLEGGLYGP
KSEELAGKFVAHDKSLFAVFSGKRGNDVLETVKIIDASKIDLTTFESSELNNFGNANVLIIDGQKIDLAG
ADFKNRKTVDINGKTMVAIACCSNLEYMKFGQLWQKEGEQTKDNSLFLQGERTATDKIPVGGNYKYVGTW
DALVSKGTNWVAEADNNRESGYRSEFDVNFGDKKVSGKLFDKGGIVPVFMINADIKGNGFTGTANTTDTG
FALDSGSSQHGNAVFSDIKVNGGFYGPTAGELGGQFHHKSDNGSVGAVFGAKRQIEK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tbpB mutant is attenuated in pigs (Baltes et al., 2002).
References
Baltes et al., 2002: Baltes N, Hennig-Pauka I, Gerlach GF. Both transferrin binding proteins are virulence factors in Actinobacillus pleuropneumoniae serotype 7 infection. FEMS microbiology letters. 2002; 209(2); 283-287. [PubMed: 12007819].