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aroA from Actinobacillus pleuropneumoniae L20

Victor ID 4036
Gene Name aroA from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848647
NCBI Protein GI 126208179
Locus Tag APL_0699
Protein Accession YP_001053404.1
Other Database IDs UniProtKB-ID: AROA_ACTP2
UniRef100: UniRef100_A3N063
UniRef90: UniRef90_A3N063
UniRef50: UniRef50_B1JXR9
UniParc: UPI000045D7A0
EMBL: CP000569
EMBL-CDS: ABN73799.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0699
eggNOG: COG0128
HOGENOM: HBG646626
OMA: GADIEWG
ProtClustDB: PRK02427
BioCyc: APLE416269:APL_0699-MONOMER
Taxonomy ID 416269
Gene Starting Position 801192
Gene Ending Position 802490
Gene Strand (Orientation) -
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
DNA Sequence 
>gi|126207488:801192-802490 Actinobacillus pleuropneumoniae L20, complete genome
GTTATGTTCTTTCCGACAACTTCTCAAATTCGGTGAAATAAGTCGGGAAGGTTTTTGCCGTACATTTTGG
ATCTAAAATCGTCACCGGTGTATCAGACAATGCAATCAACGAAAAACACATCGCCATACGGTGATCATTA
TAAGTGGCAATTTCTGCATGTTGGAATTGTGTGAGTGGCAAAGGCTGAATGCGAATAAAATCTTCGCCTT
CCTCAACGGTTGCACCGACTTTACGCAATTCGGTCGCCATCGCCGTTAAACGATCGGTTTCTTTGACACG
CCAGTTATAAATATTGCGAATCACCGTTTCCCCTTCGGCAAATAATGCGGCGGTTGCAATCGTCATCGCT
GCATCCGGAATATGGTTCATATCCATATCCACACCTTTAAGCTTACCCTGTTCCGCTTGGATAAAATCGT
CACCCCAAGTGATTTTCGCGCCCATCGCTTCCAGCACATTGGCAAACAAGCGGTCGCCTTGGATCGAATT
TTTACCAATACCGGTTACCTTTACTTTACCTTTAATCGCACCGGCTGCTAAGAAATAAGAAGCGGATGAC
GCATCGCCTTCTACCAAATATTTTTCCGGTGAGAGATAACTTTGATTACCTTTAACCACAAAGGTCTGGT
AATTTCGATTCTCAACTTTTACTCCAAAATCTTTCATCATCGCCAAGGTAATATCAATATAAGGTTTTGA
TACCAGTTCACCGATAATTTCAATTTCCATATCGCCTTCGGCAAGCGGTGCCGCCATCAATAAAGCGGTT
AAAAATTGACTTGAAATTGAACCGTCAATTTGCACCTTTCCGCCTTTTAAGCCGCTGTTTCGGATTGCAA
CCGGCGGATAACCTTCATTTTCCAAATATTGAACGCTTGCACCGGCTTGACGAAGCGCATCAACCAAATG
TTTAATCGGACGTTCTTTCATACGAGGCTCGCCGGTTAAAACTACTTCCGCTTCCGAAGATCCTTTTAAG
CAAAGTGCCGCCGTTAAAGGTCGCATTGCCGTACCGGCATTTCCTAAAAATAACGCCAAACCGTTTTTCC
AATTAAACGCACCGCCGACACCTTCAACGGTACAAACGGTTTTATCTTCCGATAATGAATAATTAACGCC
TAATGCTTTTAGTGCATTGAGCATATGGCGAATATCGTCACTGTCTAATAAATTGGTAACCTTAGTCGTC
CCTTTCGCTAAAGCGGCTAATAATAACGCACGGTTTGAAAGGCTTTTTGAGCCGGGTAAATTAATCTCGC
CCTCAACACGGCTGATCGGTGCTAATGTAATTTTTTCCA
Protein Sequence 
>gi|126208179|ref|YP_001053404.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MEKITLAPISRVEGEINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKALGVNYSLSEDKTVCTVEGVGGAFNWKNGLALFLGNAGTAMRPLTAALCLKGSSEAEVVLTGEPRMKERPIKHLVDALRQAGASVQYLENEGYPPVAIRNSGLKGGKVQIDGSISSQFLTALLMAAPLAEGDMEIEIIGELVSKPYIDITLAMMKDFGVKVENRNYQTFVVKGNQSYLSPEKYLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFANVLEAMGAKITWGDDFIQAEQGKLKGVDMDMNHIPDAAMTIATAALFAEGETVIRNIYNWRVKETDRLTAMATELRKVGATVEEGEDFIRIQPLPLTQFQHAEIATYNDHRMAMCFSLIALSDTPVTILDPKCTAKTFPTYFTEFEKLSERT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroA mutant is attenuated in pigs (Garside et al., 2002).
COG COG0128E, under E: Amino acid transport and metabolism
References
Garside et al., 2002: Garside LH, Collins M, Langford PR, Rycroft AN. Actinobacillus pleuropneumoniae serotype 1 carrying the defined aroA mutation is fully avirulent in the pig. Research in veterinary science. 2002; 72(2); 163-167. [PubMed: 12027598].