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argG from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4123
Gene Name argG from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5851696
NCBI Protein GI 165975881
Locus Tag APJL_0447
Protein Accession YP_001651474.1
Other Database IDs UniProtKB-ID: B0BTS5_ACTPJ
UniRef100: UniRef100_B0BTS5
UniRef90: UniRef90_Q4QJM0
UniRef50: UniRef50_B4TWE1
UniParc: UPI0001637440
EMBL: CP000687
EMBL-CDS: ABY69030.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0447
HOGENOM: HBG289560
OMA: GGRKEMS
ProtClustDB: PRK05370
BioCyc: APLE434271:APJL_0447-MONOMER
Taxonomy ID 434271
Gene Starting Position 486015
Gene Ending Position 487346
Gene Strand (Orientation) +
Protein Name argininosuccinate synthase
DNA Sequence 
>gi|165975457:486015-487346 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
TATGTCAGCAACAATTTTAGAATCTCTCCCGTTAGGTCAAAAAGTAGGTATCGCATTTTCAGGCGGTTTA
GATACTTCAGCAGCATTACTTTGGATGCGTAAAAAAGGTGCGGTGCCTTACGCTTACACTGCAAACTTAG
GTCAGCCGGATGAAGACGATTACAACGCAATTCCGAAAAAAGCGATGGAATACGGTGCGGAAAACGCACG
TTTAATCGACTGCCGTGCGCAATTGGCACACGAAGGTATTGCAGCGATTCAATGCGGTGCGTTCCATATT
TCAACCGGCGGTATTCCGTATTTCAATACAACACCACTTGGCCGTGCGGTAACCGGTACAATGCTTGTTG
CGGCGATGAAAGAAGATGACGTAAACATTTGGGGTGACGGTTCAACTTTTAAAGGTAACGATATCGAGCG
TTTCTATCGTTACGGCTTATTAACCAACCCGAAATTAAAAATCTACAAACCTTGGTTAGACCAACTTTTC
ATTGATGAGCTTGGCGGCCGTTTCGAAATGTCTCAATTCTTAATCGAGAACGGTTTCGACTATAAAATGT
CGGTAGAAAAAGCATACTCGACAGACTCAAATATGTTAGGTGCGACTCACGAAGCGAAAGACTTAGAAGA
ATTAAGCACCGGTATGAAAATCGTGAAACCGATTATGGGCGTAGCATTCTGGGACGAATCTGTAGAAATT
AAACCTGAAATCGTTTCGGTAACCTTCGAAGAAGGTGTGCCGGTAGCATTAAACGGTAAACGTATCGAAG
ACGCGGTTGAATTAATTTTAGAAGCAAACCGTATCGGCGGTCGCCACGGTTTAGGTATGTCGGATCAAAT
CGAAAACCGTATTATCGAAGCGAAATCTCGCGGTATCTATGAAGCACCGGGGATGGCGTTATTACACATC
GCTTACGAGCGTTTAGTAACCGGTATCCATAACGAAGATACAATCGAACAATACCGCATTAACGGTTTAC
GTTTAGGCCGTTTACTTTACCAAGGTCGTTGGTTCGATCCGCAAGCATTAATGTTACGTGAAACGGCGCA
ACGTTGGGTGGCAAAAGCGATTACCGGTACCGTTACTTTAGAATTACGTCGTGGTAACGACTTCACCATT
TTAAATACCGAGTCACCAAACTTAACTTACGAAGCGGAACGTTTAAGTATGGAAAAAGTAGAAGATGCAC
CGTTTACACCGGCGGATCGTATCGGTCAATTAACTATGCGTAACCTAGATATCGTGGATACGCGCGGTAA
ATTGGGTATCTATACCGAAACGGGTTTATTATCCGTTCAAAATAACGTATTACCGCAACTTGGTAAAAAG
TA
Protein Sequence 
>gi|165975881|ref|YP_001651474.1| argininosuccinate synthase [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MSATILESLPLGQKVGIAFSGGLDTSAALLWMRKKGAVPYAYTANLGQPDEDDYNAIPKKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTFKGNDIERFYRYGLLTNPKLKIYKPWLDQLFIDELGGRFEMSQFLIENGFDYKMSVEKAYSTDSNMLGATHEAKDLEELSTGMKIVKPIMGVAFWDESVEIKPEIVSVTFEEGVPVALNGKRIEDAVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTLELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFTPADRIGQLTMRNLDIVDTRGKLGIYTETGLLSVQNNVLPQLGKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: argG mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0137E, under E: Amino acid transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].