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pntB from Actinobacillus pleuropneumoniae L20

Victor ID 4039
Gene Name pntB from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848714
NCBI Protein GI 126208317
Locus Tag APL_0841
Protein Accession YP_001053542.1
Other Database IDs UniProtKB-ID: A3N0K1_ACTP2
UniRef100: UniRef100_A3N0K1
UniRef90: UniRef90_A3N0K1
UniRef50: UniRef50_B2TEW9
UniParc: UPI0000397E25
EMBL: CP000569
EMBL-CDS: ABN73937.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0841
eggNOG: COG1282
HOGENOM: HBG648813
OMA: VEIYVGI
ProtClustDB: PRK09444
BioCyc: APLE416269:APL_0841-MONOMER
Taxonomy ID 416269
Gene Starting Position 976068
Gene Ending Position 977516
Gene Strand (Orientation) -
Protein Name pyridine nucleotide transhydrogenase
DNA Sequence 
>gi|126207488:976068-977516 Actinobacillus pleuropneumoniae L20, complete genome
ATTAGCTATTTAATGCTCTTAAAATGTCATCCACACGCTCTTTCGCATCACCGAATAACATTTGAGTATT
TTCTTTGAAGAATAGAGGATTTTGAACGCCTGCGTAACCAACCGCCATTGAACGTTTGAATACGATAACG
TTTTGTGCTTTCCACACTTCTAATACCGGCATACCTGCGATTGGGCTTGACGGATCATCTAATGCCGCTG
GGTTTACCGTGTCATTTGCACCGATAACCAATACGACATCGGTTTCTTCGAAATCATCATTGATTTCATC
CATTTCAAGTACCACATCGTAAGGCACTTTCGCTTCCGCAAGTAATACGTTCATATGACCCGGTAAACGA
CCTGCGACAGGGTGAATACCGAAACGCACATTCACACCTTTCTCACGTAATTTCGCCGTAATTTCCGCAA
CCGGATATTGTGCTTGTGCCACCGCCATACCGTATCCCGGAGTGATAATCACAGAACTTGCATTTTTCAG
CATTTCCGCCACTTCTTCCGCAGTAGTTTCACGATGCTCACCTTGTTCTTCATCACCTGAGCTTGCTTTA
ACTTCCGTACCGAAGCCGCCTGCAATCACGCTGATAAACGAGCGGTTCATTGCTTTACACATAATGTAAG
ACAAAATCGCACCGGACGAACCTACTAACGCACCGGTTACAATGAGCAAGTCATTACTTAACATAAAACC
GGCCGCCGCCGCCGCCCAACCCGAATATGAATTCAGCATTGAAACCACTACCGGCATATCCGCACCGCCG
ATAGACGATACTAAGTGCCAACCGAATACTAATGCGATTACCGTCATAATCAACACCGGGAAAATATTCT
CAGGGTGATTTAAGAAGACGATCATTAATAATGCGGAAACGATTAATGCCGCTAAGTTCCATTTGTGTTT
ATGCGGAATATTTAATGCAGCCGAAGACACTTTACGACCGAATAATTTACCGCTTAATTTACCGAATGCC
ACTAATGAACCGGAGAATGTTACCGCACCGATAAAGATACCGAGGAACACTTCAACATTATGAATGTTAG
CGAGTGTCGCTTGTTCGGCTTGGAATGCCGCTAGTGCCACTTCATCTAAGTTTGCCGGTGGAATCGCATC
TACGTGTAAACCGTAGCTGTTAAAACCGACTAATACCGCAGCTAAACCGACAAAGCTATGTAGAATCGCC
ACTAGTTCCGGCATTTCCGTCATTTCAACTTTTACGGCTTTTCTCACACCGATAAATCCGCCGATTGCCA
TTGCGATTAAGATCCAAAGCGTACCTTGCGATTGCGGACCGAAGATAGTTGCGACTAACGCAATCGCCAT
CCCGACGATACCGTACCAACAACCCGCTTTTGCCGTTTCGTGTTTAGAAAGTCCTGCTAAACTCATAATA
AAGAGAATCGCAGCAATAATATATGCGGCCGTTACAAATCCAAAAGACA
Protein Sequence 
>gi|126208317|ref|YP_001053542.1| pyridine nucleotide transhydrogenase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSFGFVTAAYIIAAILFIMSLAGLSKHETAKAGCWYGIVGMAIALVATIFGPQSQGTLWILIAMAIGGFIGVRKAVKVEMTEMPELVAILHSFVGLAAVLVGFNSYGLHVDAIPPANLDEVALAAFQAEQATLANIHNVEVFLGIFIGAVTFSGSLVAFGKLSGKLFGRKVSSAALNIPHKHKWNLAALIVSALLMIVFLNHPENIFPVLIMTVIALVFGWHLVSSIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTEVKASSGDEEQGEHRETTAEEVAEMLKNASSVIITPGYGMAVAQAQYPVAEITAKLREKGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFEETDVVLVIGANDTVNPAALDDPSSPIAGMPVLEVWKAQNVIVFKRSMAVGYAGVQNPLFFKENTQMLFGDAKERVDDILRALNS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pntB mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG1282C, under C: Energy production and conversion
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].