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argG from Actinobacillus pleuropneumoniae L20

Victor ID 4053
Gene Name argG from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849166
NCBI Protein GI 126207906
Locus Tag APL_0422
Protein Accession YP_001053131.1
Other Database IDs UniProtKB-ID: A3MZE0_ACTP2
UniRef100: UniRef100_A3MZE0
UniRef90: UniRef90_Q4QJM0
UniRef50: UniRef50_B4TWE1
UniParc: UPI0000F2840F
EMBL: CP000569
EMBL-CDS: ABN73526.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0422
eggNOG: COG0137
HOGENOM: HBG289560
OMA: GGRKEMS
ProtClustDB: PRK05370
BioCyc: APLE416269:APL_0422-MONOMER
Taxonomy ID 416269
Gene Starting Position 479095
Gene Ending Position 480426
Gene Strand (Orientation) +
Protein Name argininosuccinate synthase
DNA Sequence 
>gi|126207488:479095-480426 Actinobacillus pleuropneumoniae L20, complete genome
TATGTCAGCAACAATTTTAGAATCTCTCCCGTTAGGTCAAAAAGTAGGTATCGCATTTTCAGGCGGTTTA
GATACTTCAGCAGCATTACTTTGGATGCGTAAAAAAGGTGCGGTGCCTTACGCTTACACTGCAAACTTAG
GTCAGCCGGATGAAGACGATTACAACGCAATTCCGAAAAAAGCGATGGAATACGGTGCGGAAAACGCACG
TTTAATCGACTGCCGTGCGCAATTGGCACACGAAGGTATTGCAGCGATTCAATGCGGTGCGTTCCATATT
TCAACCGGCGGTATTCCGTATTTCAATACAACACCACTTGGCCGTGCGGTAACCGGTACAATGCTTGTTG
CGGCGATGAAAGAAGATGACGTAAACATTTGGGGTGACGGTTCAACTTTTAAAGGTAACGATATCGAGCG
TTTCTATCGTTACGGCTTATTAACCAACCCGAAATTAAAAATCTACAAACCTTGGTTAGACCAACTTTTC
ATTGATGAGCTTGGCGGCCGTTTCGAAATGTCTCAATTCTTAATCGAGAACGGTTTCGACTATAAAATGT
CGGTAGAAAAAGCATACTCGACAGACTCAAATATGTTAGGTGCGACTCACGAAGCGAAAGACTTAGAAGA
ATTAAGCACCGGTATGAAAATCGTGAAACCGATTATGGGCGTAGCATTCTGGGACGAATCTGTAGAAATT
AAACCTGAAACCGTTTCGGTAACCTTCGAAGAAGGTGTGCCGGTAGCATTAAACGGTAAACGTATCGAAG
ACGCGGTTGAATTAATCTTAGAAGCAAACCGTATCGGCGGTCGCCACGGTTTAGGTATGTCGGATCAAAT
CGAAAACCGTATTATCGAAGCGAAATCTCGCGGTATCTATGAAGCACCAGGGATGGCGTTATTACACATC
GCTTACGAGCGTTTAGTAACCGGTATCCATAACGAAGATACAATCGAACAATACCGCATTAACGGTTTAC
GTTTAGGCCGTTTACTTTACCAAGGTCGTTGGTTCGATCCGCAAGCGTTAATGTTACGCGAAACGGCTCA
ACGTTGGGTGGCAAAAGCGATTACCGGTACCGTTACTTTAGAATTACGTCGTGGTAATGATTTCACGATT
TTAAATACCGAGTCACCAAACTTAACTTACGAAGCAGAACGTTTAAGTATGGAAAAAGTAGAAGATGCAC
CGTTCACACCGGCGGATCGTATCGGTCAATTAACTATGCGTAACCTAGATATCGTGGATACGCGCGGTAA
ATTAGGTATCTATACCGAAACGGGTTTATTATCCGTTCAAAATAACGTATTACCGCAACTTGGTAAAAAG
TA
Protein Sequence 
>gi|126207906|ref|YP_001053131.1| argininosuccinate synthase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSATILESLPLGQKVGIAFSGGLDTSAALLWMRKKGAVPYAYTANLGQPDEDDYNAIPKKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHISTGGIPYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTFKGNDIERFYRYGLLTNPKLKIYKPWLDQLFIDELGGRFEMSQFLIENGFDYKMSVEKAYSTDSNMLGATHEAKDLEELSTGMKIVKPIMGVAFWDESVEIKPETVSVTFEEGVPVALNGKRIEDAVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYRINGLRLGRLLYQGRWFDPQALMLRETAQRWVAKAITGTVTLELRRGNDFTILNTESPNLTYEAERLSMEKVEDAPFTPADRIGQLTMRNLDIVDTRGKLGIYTETGLLSVQNNVLPQLGKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: argG mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0137E, under E: Amino acid transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].