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lon from Actinobacillus pleuropneumoniae L20

Victor ID 4069
Gene Name lon from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849930
NCBI Protein GI 126207860
Locus Tag APL_0376
Protein Accession YP_001053085.1
Other Database IDs UniProtKB-ID: A3MZ94_ACTP2
UniRef100: UniRef100_A3MZ94
UniRef90: UniRef90_A3MZ94
UniRef50: UniRef50_E1VK96
UniParc: UPI0000F28931
EMBL: CP000569
EMBL-CDS: ABN73480.1
RefSeq_NT: NC_009053.1
MEROPS: S16.001
GenomeReviews: CP000569_GR
KEGG: apl:APL_0376
eggNOG: COG0466
HOGENOM: HBG566281
OMA: HTFQDHY
ProtClustDB: CLSK918906
BioCyc: APLE416269:APL_0376-MONOMER
Taxonomy ID 416269
Gene Starting Position 425662
Gene Ending Position 428070
Gene Strand (Orientation) -
Protein Name ATP-dependent protease La
DNA Sequence 
>gi|126207488:425662-428070 Actinobacillus pleuropneumoniae L20, complete genome
ATTATTGAATAGCCGCTTTTGAGCGAGTTTTTTTCACTTTAATCGTTTGTGATTTAGGAGAGATCACCTC
AATCCCCATCGGCGGATTTTCTAGTGCAATCGCTAACACTTCGTCAATCGTTTCCACCGAATGAATAGCC
AATGCCGCTTTGGCATTTTCAGGAATCTCTTCCAGATCTTTTTCGTTGTCTTTCGGAATAATCACGGTAG
TAATGCCGCCACGGTGTGCCGCCAATAATTTCTCTTTTAAGCCGCCGATCGGTAATACTTTACCACGTAA
GCTAATTTCACCGGTCATCGCCACTTCTTTGCGAACAGGATTGCCGGTTAAACTTGAAATTAATGCGGTA
CACATTGCAATACCTGCACTCGGGCCGTCTTTCGGCGTTGCGCCGTCCGGCACGTGTACGTGAATATCAC
GTTTTTCATAGAAGTCATCCGCAATGCCTAATTGTGCGGATCTTGCACGTACCACCATCATTGCCGCTTG
AATCGATTCTTTCATCACATCGCCTAATGAACCGGTAAATGAGAATTTACCTTTACCGCCGACCGAAGTG
GTTTCGATGGTGAGTAAATCGCCGCCGACTTCCGTCCAAGCTAAGCCGGTTACTTCACCGACACGGTTTT
GGCTGTCCATTTTACCGTAATCAAAACGTTTTACACCCAAGTAATCGGCGATATTGTCTTCGGTTACCGT
AATTGATTTGACTTTTTTGTCCAACACCAAAGTTTTCACCGCTTTACGACAGATCTTAGCAATTTCACGT
TCAAGACTACGCACACCGGCTTCACGAGTGTAGTAACGAATAATGCTTAAAATAGCACTATCTTCGATAG
TTAATTCACCCGCTTTTAAGCCGTTATTTTCTTGCTGTTTGGCAATTAAGTGGTCACGGGCAATGTGCAT
TTTCTCATCTTCGGTATAACCGGAAAGACGAATCACTTCCATACGGTCGAGTAATGCCGGCGGAATATTC
ATTGAGTTTGACGTTGCTACGAACATTACGTCGGAAAGATCGTAATCGACTTCTAAATAATGGTCGTTAA
ACGCTTTGTTTTGCTCCGGATCTAATACTTCAAGTAATGCCGAAGCCGGGTCACCGCGCATATCTTGCGC
CATTTTGTCGATTTCATCGAGCAAGAACAACGGATTTTTCACGCCGACTTTTGCCATTTTCATCATTAAT
GAACCCGGCATAGAACCGATATAAGTACGGCGATGACCGCGGATTTCCGCTTCGTCACGCACACCGCCTA
ACGCCATACGAACATATTTACGACCGGTTGCATTAGCGATAGATTGCCCAAGAGAGGTTTTACCCACACC
CGGAGGACCGACTAAGCAAAGAATCGGGCCTTTAAGTTTGTTTAAACGGCTTTGTACCGCAAGGTATTCG
ACAATGCGCTCTTTAACACGCTCCAAGCCATAGTGATCTTTGTCTAAAATTTCTTGCGCTTTCGCCAAGT
CTTTTTTCACAGTTGATTTTTTGTTCCACGGCATTTTTAAGACCCAATCGATATAGCCGCGTACGACGGT
CGCTTCGGAAGAACTTTGCGGCATCGCTTTTAACTTTTTAAACTCGCTATCCAGTTTTTCTTTTACTTCG
AGCGGTAGCTTCGCTTCTTTGATCTGTTCTTTTAATTTATCCAGTTCGGTTTGTTCGGCATCTTCACCGT
TACCAAGCTCTTTTTGAATCGCTTTAATTTGCTCGTTTAAATAATAATCGCGTTGGTTTTTTTCCATTTG
CTGTTTCACACGATTACGAATACGCGTTTCGGTTTCTAGCGAATCCAACTCGGTTGCCATCGCAACTAAT
AATGCTTCAAAACGAGCAATTAAGTTAGTTTCTTCTAATAATGCTTGTTTTTTCTGTACGGATGCAATTA
AGTTTGAAGCCATTGTGTCTGCAAGGCGGTCTTCCAATGAAATTTTTTGTAACTTAGGTAGAATTTCCGC
CGGAATTTTCTTGTTATTTTTTACATAACCTTCAAATTCATTTAATGCAGCTCTTGCAATTGTTTTTAAT
TCGTCGTTTTCATCTTCGTATTCAGAAATTAAAGGTTGTACGCCCGCCCAGAAGCCGTTTTCATCATCAT
GGATATGCTCGATTTTAGCGCGTTGCTGACCTTCAACCAGTACTTTGACCGTACCGTCCGGTAGATTCAA
CATTTGAATAATATTAGCGATCACGCCAACGGAATACACATCTTCTGTTGTCGGTTCTTCTTTATTAGGA
TCTTGTTGTGTAACAAGAAATAATTGTTTATTTGAATCCATCGCCGCACGTAAAGCCTGAATGGATTTTT
CACGACCTACGAATAACGGCATAACCATATAAGGAAAGACCACTACATCACGTAATGGAAGAAGTGGCAA
TTCAATTGCTTTCTTTTTTCTTGGTGCCA
Protein Sequence 
>gi|126207860|ref|YP_001053085.1| ATP-dependent protease La [Actinobacillus pleuropneumoniae serovar 5b str. L20] MAPRKKKAIELPLLPLRDVVVFPYMVMPLFVGREKSIQALRAAMDSNKQLFLVTQQDPNKEEPTTEDVYSVGVIANIIQMLNLPDGTVKVLVEGQQRAKIEHIHDDENGFWAGVQPLISEYEDENDELKTIARAALNEFEGYVKNNKKIPAEILPKLQKISLEDRLADTMASNLIASVQKKQALLEETNLIARFEALLVAMATELDSLETETRIRNRVKQQMEKNQRDYYLNEQIKAIQKELGNGEDAEQTELDKLKEQIKEAKLPLEVKEKLDSEFKKLKAMPQSSSEATVVRGYIDWVLKMPWNKKSTVKKDLAKAQEILDKDHYGLERVKERIVEYLAVQSRLNKLKGPILCLVGPPGVGKTSLGQSIANATGRKYVRMALGGVRDEAEIRGHRRTYIGSMPGSLMMKMAKVGVKNPLFLLDEIDKMAQDMRGDPASALLEVLDPEQNKAFNDHYLEVDYDLSDVMFVATSNSMNIPPALLDRMEVIRLSGYTEDEKMHIARDHLIAKQQENNGLKAGELTIEDSAILSIIRYYTREAGVRSLEREIAKICRKAVKTLVLDKKVKSITVTEDNIADYLGVKRFDYGKMDSQNRVGEVTGLAWTEVGGDLLTIETTSVGGKGKFSFTGSLGDVMKESIQAAMMVVRARSAQLGIADDFYEKRDIHVHVPDGATPKDGPSAGIAMCTALISSLTGNPVRKEVAMTGEISLRGKVLPIGGLKEKLLAAHRGGITTVIIPKDNEKDLEEIPENAKAALAIHSVETIDEVLAIALENPPMGIEVISPKSQTIKVKKTRSKAAIQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lon mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0466O, under O: Posttranslational modification, protein turnover, chaperones
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].