Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

apxIIIB

Victor ID 4941
Gene Name apxIIIB
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 2
NCBI Nucleotide GI 470686
Genbank Accession AAA21925.1
Other Database IDs CDD:30270
CDD:162558
CDD:193863
CDD:73011
Taxonomy ID 34063
Gene Strand (Orientation) ?
Protein Name RTX toxin
Protein Note A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the 'double-glycine'...; cd02417
DNA Sequence
Protein Sequence 
>gi|470686|gb|AAA21925.1| RTX toxin [Actinobacillus pleuropneumoniae serovar 2]
MESQMPFNEKIDYGLHALVILAQYHNVAVNPEEVKHKFDLDGKGLDLVAWLLAAKSLELKVKRVKKSIER
LPFIHLPALIWRDDGQHVILMKIDTQTNRYLIFDLEERNPKVLSAAEFHEIFQGGMILITSRASIMGQLA
KFDFTWFIPAVIKYRKIFVETIIVSIFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVVIFEI
VLSGLRTYIFSHSTSRIDVELGAKLFRHLLALPISYFENRRVGDTVARVRELDQIRNFLTGQALTSVLDL
LFSFIFFAVMWYYSPKLTIVILLSLPCYIAWSIFISPILRRRLDEKFARNADNQSFLVESVSAIDTIKAL
AVTPQMTNIWDKQLASYVSADFRVTVLATIGQQGVQLIQKTVMIINLWLGAHLVISGDLSIGQLITFNML
SGQVIAPVVRLAQLWQDFQQVGISITRLGDVLNSPTENYQGKLSLPEIFGDIAFKHIRFRYKPDAPIILD
DVNLSVKQGEVIGIVGRSGSGKSTLTKLLQRFYIPENGQVLIDGHDLALADPNWLRRQIGVVLQDNVLLN
RSIRDNIALTDPSMSMERVIYAAKLAGAHDFISELREGYNTIVGELGAGLSGGQRQRIAIARALVNNPRI
LIFDEATSALDYESEHIIMQNMQKICHGRTVIIIAHRLSTVKNADRIIVMEKGHIVEQGKHNQLLENENG
LYYYLNQLQSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs (Park et al., 2009).
References
Park et al., 2009: Park C, Ha Y, Kim S, Chae C, Ryu DY. Construction and characterization of an Actinobacillus pleuropneumoniae serotype 2 mutant lacking the Apx toxin secretion protein genes apxIIIB and apxIIID. The Journal of veterinary medical science / the Japanese Society of Veterinary Science. 2009; 71(10); 1317-1323. [PubMed: 19887737].