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nqrA from Actinobacillus pleuropneumoniae L20

Victor ID 4035
Gene Name nqrA from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848604
NCBI Protein GI 126207638
Locus Tag APL_0150
Protein Accession YP_001052863.1
Other Database IDs UniProtKB-ID: NQRA_ACTP2
UniRef100: UniRef100_A3MYM2
UniRef90: UniRef90_A3MYM2
UniRef50: UniRef50_Q1QX86
UniParc: UPI00000B51D7
EMBL: CP000569
EMBL-CDS: ABN73258.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0150
eggNOG: COG1726
HOGENOM: HBG413878
OMA: EYGPILR
ProtClustDB: PRK05352
BioCyc: APLE416269:APL_0150-MONOMER
Taxonomy ID 416269
Gene Starting Position 168085
Gene Ending Position 169434
Gene Strand (Orientation) +
Protein Name Na(+)-translocating NADH-quinone reductase subunit A
DNA Sequence 
>gi|126207488:168085-169434 Actinobacillus pleuropneumoniae L20, complete genome
TATGATTACAATCAAGAAAGGCTTGGATTTACCTATCGCAGGTACACCGGCACAAGTAATCCATAACGGC
AATACCGTTAATGAAGTTGCGATGCTTGGCGAAGAATATGTGGGTATGCGTCCTTCAATGAAAGTTCGTG
AAGGCGATGTAGTGAAAAAAGGTCAGGTTCTTTTTGAAGATAAAAAGAATCCGGGCGTTGTATTTACTGC
TCCTGCAAGCGGTACCGTGGTTACTATTAACCGCGGTGAAAAGCGTGTTCTTCAGTCGGTCGTGATTAAA
GTTGAGGGTGATGAGCAAATTACCTTTACTCGCTATGAAGCTGCGCAATTAGCGTCGCTATCAGCCGAGC
AAGTGAAACAAAATCTTATCGAATCGGGTTTATGGACTGCATTCCGTACTCGTCCGTTCAGTAAGGTTCC
CGCATTGGACGCGATTCCGTCATCAATCTTTGTCAATGCAATGGATACCAATCCGTTAGCGGCGGATCCG
GAAGTGGTTTTAAAAGAGTACGAAACCGATTTTAAAGACGGTTTAACTGTTTTAACCCGTTTATTTAACG
GTCAAAAACCGGTTTACTTATGTAAAGACGCGGACAGCAATATCCCGTTAAGTCCGGCGATTGAAGGTAT
CACAATTAAGTCGTTTAGCGGTGTTCATCCTGCCGGTTTAGTCGGTACGCATATCCACTTTGTTGATCCC
GTAGGGGCGACCAAACAAGTTTGGCACTTAAATTATCAAGATGTGATTGCTATCGGTAAATTATTTACTA
CAGGCGAACTCTTTACCGACCGTATTATTTCGCTTGCCGGTCCGCAAGTGAAAAATCCTCGTTTAGTACG
TACGCGTCTTGGTGCGAATCTTTCCCAATTAACCGCAAATGAGTTAAATGCCGGTGAAAACCGTGTGATT
TCAGGTTCGGTATTGAGCGGTGCGACTGCGGCGGGTCCGGTTGATTACTTAGGCCGTTACGCATTACAAG
TATCCGTACTGGCGGAAGGTCGTGAGAAAGAGTTATTCGGTTGGATTATGCCGGGTTCGGATAAATTCTC
CATTACCCGTACCGTGTTAGGCCACTTCGGTAAAAAATTATTTAACTTCACTACGGCAGTTCACGGCGGT
GAACGTGCAATGGTGCCAATCGGTGCGTATGAGCGTGTAATGCCGTTAGATATTATTCCTACGTTATTAC
TTCGTGATTTAGCTGCCGGCGATACCGATTCTGCACAAAACTTAGGTTGTTTAGAGCTGGATGAAGAAGA
TTTGGCATTATGTACTTATGTTTGCCCGGGTAAAAATAACTACGGTCCGATGTTACGTGCTGCGTTAGAG
AAGATCGAGAAGGAAGGTTA
Protein Sequence 
>gi|126207638|ref|YP_001052863.1| Na(+)-translocating NADH-quinone reductase subunit A [Actinobacillus pleuropneumoniae serovar 5b str. L20] MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLAADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQVWHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYLGRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ngrA mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG1726C, under C: Energy production and conversion
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].