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lpdA from Actinobacillus pleuropneumoniae L20

Victor ID 4062
Gene Name lpdA from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849746
NCBI Protein GI 126208249
Locus Tag APL_0771
Protein Accession YP_001053474.1
Other Database IDs UniProtKB-ID: A3N0D3_ACTP2
UniRef100: UniRef100_A3N0D3
UniRef90: UniRef90_P43784
UniRef50: UniRef50_P0A9P2
UniParc: UPI000045D845
EMBL: CP000569
EMBL-CDS: ABN73869.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0771
eggNOG: COG1249
HOGENOM: HBG515043
OMA: PFIPEDP
ProtClustDB: PRK06467
BioCyc: APLE416269:APL_0771-MONOMER
Taxonomy ID 416269
Gene Starting Position 883953
Gene Ending Position 885377
Gene Strand (Orientation) -
Protein Name dihydrolipoamide dehydrogenase
DNA Sequence 
>gi|126207488:883953-885377 Actinobacillus pleuropneumoniae L20, complete genome
ATTAACGTTTTTTCGCTTTTGCATTTGGTAAGTCTGTAATAGAGCCTTCAAATACTTCCGCAGCTAAACC
TACCGATTCGTGTAATGTAGGATGAGCATGGATAGTTAAAGCGATATCTTCCGCATCGCAACCCATTTCG
ATTGCAAGACCGATTTCACCTAATAATTCACCGCCGTTGCTACCTACGATTGCACCGCCAAGTAAACGGT
GAGTATCTTTATCGAAGATAAGTTTAGTCATACCTTCCGAACATTCGGAAGCGATCGCACGACCTGATGC
AGCCCAAGGGAATTTAGCCACTTCGTAGTTTAAGCCTTCTTGCTTACACTCTTTCTCCGTTTTACCTACC
CAAGCAACTTCCGGCTCTGTATAAGCGATTGAAGGAATCACTTTAGGATCAAAATAGTGTTTTTGACCGG
CAATCACTTCTGCCGCTACATGACCTTCGTGAACACCTTTGTGTGCTAACATCGGCTGACCGACGATATC
ACCGATAGCAAAGATATGCGGTACGTTGGTACGCATTTGTTTATCCACTGCGATGAAACCGCGATCATCA
ACATTCACGCCCGCTTTACCCGCATCGATTAATTTACCGTTCGGTACACGACCGATAGCGACTAATACCG
CATCGTAACGTTTAGTATCGTTACATGCTTTACCTTCCATTGAAACATAGATACCGTCATCTTTCGCTTC
AACCGCAGTTACTTTAGTTTCAAGCATTAACTTGAATTTTTTCTCGATTTGTTTGGTGTAGATAGCTACA
ACATCTTTATCTGCTGCAGGAATCACTTGGTCAAACATCTCAACCACTTCAACTTCCGAACCTAAAGCGT
TATACACGGTACCCATTTCTAAACCGATGATACCACCGCCCATAATGAGTAATTTTTTCGGTACTTCTTT
TAATTTAAGTGCATCCGTAGAATCCCACACACGCGGATCTTCGTGTGGAATGAACGGAAGCTGAATCGGA
CGAGAACCGGCTGCAATAATTGCATTATCAAATTTAATCGTTGTCGGATTACCGTCACGGTCACGAGCTA
CTAAAGTATTCGGATCGGTAAACGCCGCTAAACCTTCCACTACTGTTACTTTACGTGCTTTAGCCATACC
CGCTAAACCGCCGGTTAATTTAGAAACAACCGCTTCTTTACCCGCACGCACTTTATCTAAATCAATGTTG
GGCTCACCGAAAGTAATACCGTTTTTCTCTGCGTGTTTTGCTTCTTCGATAACTTTTGCAACGTGTAATA
ATGCTTTAGACGGAATACAACCTACGTTTAAGCATACACCGCCCAAAGTTGAATAACGTTCGACAATTAC
TGTTTCTAAGCCTAAGTCGGCACAACGGAATGCCGCTGAATAACCGGCAGGACCCGCACCAAGTACCACG
ACTTGCGTTTTGATTTCTTTGCTCA
Protein Sequence 
>gi|126208249|ref|YP_001053474.1| dihydrolipoamide dehydrogenase [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSKEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYSTLGGVCLNVGCIPSKALLHVAKVIEEAKHAEKNGITFGEPNIDLDKVRAGKEAVVSKLTGGLAGMAKARKVTVVEGLAAFTDPNTLVARDRDGNPTTIKFDNAIIAAGSRPIQLPFIPHEDPRVWDSTDALKLKEVPKKLLIMGGGIIGLEMGTVYNALGSEVEVVEMFDQVIPAADKDVVAIYTKQIEKKFKLMLETKVTAVEAKDDGIYVSMEGKACNDTKRYDAVLVAIGRVPNGKLIDAGKAGVNVDDRGFIAVDKQMRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGQKHYFDPKVIPSIAYTEPEVAWVGKTEKECKQEGLNYEVAKFPWAASGRAIASECSEGMTKLIFDKDTHRLLGGAIVGSNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNAKAKKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpdA mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG1249C, under C: Energy production and conversion
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].