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frpB from Actinobacillus pleuropneumoniae L20

Victor ID 4047
Gene Name frpB from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848963
NCBI Protein GI 126207764
Locus Tag APL_0276
Protein Accession YP_001052989.1
Other Database IDs UniProtKB-ID: A3MYZ8_ACTP2
UniRef100: UniRef100_A3MYZ8
UniRef90: UniRef90_A3MYZ8
UniRef50: UniRef50_A3MYZ8
UniParc: UPI00003978CA
EMBL: CP000569
EMBL-CDS: ABN73384.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_0276
eggNOG: COG1629
HOGENOM: HBG296623
OMA: KANGNIY
ProtClustDB: CLSK878324
BioCyc: APLE416269:APL_0276-MONOMER
Taxonomy ID 416269
Gene Starting Position 302892
Gene Ending Position 304862
Gene Strand (Orientation) +
Protein Name iron-regulated outer membrane protein B
DNA Sequence 
>gi|126207488:302892-304862 Actinobacillus pleuropneumoniae L20, complete genome
AATGCATAAAAAAACAATATTTAAATTAAGCTTAATTAGTTTAGCCGTCGCCGGCTATGCGGAAGCTAAT
CAAGCTACACTTGATACGGTGAAGGTTCAAGCTCAACCTACGGTGAATCATACTAGAAATATCAGTAACC
TGCGCGAATTACTGGCTAATCGTACGGACATTAACGTCGGTGGAGGTAGCGTGTCCGCACAATACATTTC
GATTCGCGGATCAGGACAAGATCGTATCGGTATGATTGTCGATAATACTTCGACAAATACTCAACAGTGG
TATCACCAAGGTCGTTTCCAACTGGATCCGTCTATGGTGAAATCGATTAAAATCGATAAGGGCGCCGGTT
CCGCCAGTGCCGGTATCGGTATAACGGACGGTGTAATCCGTGCGGAAACGGTATCGGCAAAAGATTTATT
GAAAGACGGCAGATCATTCGGTGCGCGTATCGGTTCCGAATATAACAGTAATCGCGGCATTAACGATTCG
CTTTCACTCTATGGACAAGCGAATAATCTGGATGTATTGCTATTAGGCAGTTGGGGAGACGATAAAAACT
ATAAGGCGGGTAAAGGTTATTCGGATGCGGTGAATAAAAATAGCCGAGTAGTGAATAATACCGCTCGTCG
TCAAGGTAATTATTTGGCGAAATTCGGCTATGATATTACCGATAAACAGCGTATCGGCTTAAGTTTCCGT
CAAGAGTCGTTTTATGGTGCGGGACAAGATCGTTTCGAGATGATTTTTAATAGCCGCCCGGTAAATGCGA
ACACGACCAAACGTACCTACAACCTTGAGTATGATGCGAAAGACATCGGCTTTGCTCGAGACGTTAAAGC
GAATGTGTTCCATATTTTAGGGACGGATAAGCGAGAAGATTATCAGCAAAATAAATTAACCGGTTATCAA
CGTAGTTCTAAAACCAAAACAACGGGGGCTAATTTAGGCTTTACCAGCGAATTTGGCGGAGAGCATCTGT
TTAAATATGGTGTGAATCTGCGTAAAGAGCAGACAGGTAGTCAGAATTCGTTCGGCAATATTAAAGGCGA
ACAAAAATTCGAATACGGACTATATGCCGAAGGGATTTGGTCTTTAGGTAAAGTGCTGACCTTAACCACA
GGGTTACGTTATGATTACTATGATTTGGATACAGCGGGTAAAGTGGATAAAAACGGTAAACCGCTTGCCG
GTAATAAATCGGTATCCGATAAAAGATTAAATCCGAGTTTCGGATTGATTTGGGACATTACACCGAATTT
TGCTTTGAATGCTAAATTAAATTATGCAAGTCGCAGCCCTATTTTAGCTTCGGCAAATACCATAACCGAT
AACCGCGGTTCATTAGATAAAGCCAGAGGCTTACGTTTTATCGATCCTAAATTGAAAACCGAAGACGTAC
GTTTGGCGGAAGTCGGTTTTGAATGGAAATATGCCGATTTTAATTTAAAAGGCAGCGTGTTCGAGCAAAG
AGTTAAAAACTTCTATCAAACGACCAACAGTATCATTAGCAATGCGGGAACCTTAAAAACGAAAGGTTAT
GAAGCCGAGTTGGATTATCAATGGAACGCATTAAAATTAACCGCCGGTGTGGCGTATGCCGATCCGAAAG
CGGACTTTGCGCTTTCTAATGATCCGCTGAATGTTATTCCGCAAGGTCGTCAATGGAGTACCGGTGTTTC
GTATAAATTTGTTGAACCGAATTTAGAGATCGGTTGGTTAGGTCGCTATGCTCAGTCTAAAGAGTATAAA
ACGGGCGCTGCGCCGAAAGTCGAAACGAGAAGACGTATCGGATACGGCGTACATGATATTTTCGTAAACT
GGCAGCCGCTTAATCAAGACAACTTCAATGTGAATTTCACGGTAAAAAACATCGGTAATAAATTCTATCG
TAGTCACAGCCAAAGAAATCTTGAAGTCACGCCGCCAAGCCCGGGACGTGAGTTTAAAATCGGTATGAAC
TATAGTTTCTA
Protein Sequence 
>gi|126207764|ref|YP_001052989.1| iron-regulated outer membrane protein B [Actinobacillus pleuropneumoniae serovar 5b str. L20] MHKKTIFKLSLISLAVAGYAEANQATLDTVKVQAQPTVNHTRNISNLRELLANRTDINVGGGSVSAQYISIRGSGQDRIGMIVDNTSTNTQQWYHQGRFQLDPSMVKSIKIDKGAGSASAGIGITDGVIRAETVSAKDLLKDGRSFGARIGSEYNSNRGINDSLSLYGQANNLDVLLLGSWGDDKNYKAGKGYSDAVNKNSRVVNNTARRQGNYLAKFGYDITDKQRIGLSFRQESFYGAGQDRFEMIFNSRPVNANTTKRTYNLEYDAKDIGFARDVKANVFHILGTDKREDYQQNKLTGYQRSSKTKTTGANLGFTSEFGGEHLFKYGVNLRKEQTGSQNSFGNIKGEQKFEYGLYAEGIWSLGKVLTLTTGLRYDYYDLDTAGKVDKNGKPLAGNKSVSDKRLNPSFGLIWDITPNFALNAKLNYASRSPILASANTITDNRGSLDKARGLRFIDPKLKTEDVRLAEVGFEWKYADFNLKGSVFEQRVKNFYQTTNSIISNAGTLKTKGYEAELDYQWNALKLTAGVAYADPKADFALSNDPLNVIPQGRQWSTGVSYKFVEPNLEIGWLGRYAQSKEYKTGAAPKVETRRRIGYGVHDIFVNWQPLNQDNFNVNFTVKNIGNKFYRSHSQRNLEVTPPSPGREFKIGMNYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: frpB mutant is avirulent in pigs (Buettner et al., 2009).
COG COG1629P, under P: Inorganic ion transport and metabolism
References
Buettner et al., 2009: Buettner FF, Bendalla IM, Bossé JT, Meens J, Nash JH, Härtig E, Langford PR, Gerlach GF. Analysis of the Actinobacillus pleuropneumoniae HlyX (FNR) regulon and identification of iron-regulated protein B as an essential virulence factor. Proteomics. 2009; 9(9); 2383-2398. [PubMed: 19343711].