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guaA from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4132
Gene Name guaA from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5851973
NCBI Protein GI 165976006
Locus Tag APJL_0585
Protein Accession YP_001651599.1
Other Database IDs UniProtKB-ID: GUAA_ACTPJ
UniRef100: UniRef100_B0BUF0
UniRef90: UniRef90_A3MZV8
UniRef50: UniRef50_Q3JR65
UniParc: UPI000163764B
EMBL: CP000687
EMBL-CDS: ABY69155.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0585
HOGENOM: HBG391775
OMA: MKLVEPL
ProtClustDB: PRK00074
BioCyc: APLE434271:APJL_0585-MONOMER
Taxonomy ID 434271
Gene Starting Position 635324
Gene Ending Position 636895
Gene Strand (Orientation) -
Protein Name GMP synthase
DNA Sequence 
>gi|165975457:635324-636895 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
TTTATTCCCACTCAATCGTTGCAGGCGGTTTGCCTGAAACGTCATATACCACGCGAGAAATGCCGTTTAC
TTCATTGATAATACGGTTTGAGATTTTACCGAGTAAATCGTATGGTAAATGCGCCCAATGTGCGGTCATA
AAGTCGATAGTTTCTACCGCACGGAGTGAAACAACCCAGTCGTATTTACGACCGTCACCCATTACACCCA
CTGATTTTACCGGAAGGAATACGGTAAACGCTTGGCTTACTTTGTAATACCAATCCGCTTTGTAGAGCTC
TTCGATAAAGATTGCATCCGCTTTACGCAGTAAATCGCAGTATTCTTTCTTGATTTCACCTAATACACGC
ACACCTAAACCCGGACCCGGGAATGGGTGGCGATTTAACATTTCTGCCGGTAAACCAAGTGCTAAACCGA
TTTTACGTACTTCATCTTTGAATAATTCACGTAACGGTTCCACTAAACCGAGTTTCATATAATCCGGTAA
GCCGCCTACGTTATGGTGAGATTTAATCACGTGTGCTTTACCGGTTTTGCTCGCAGCAGATTCGATAACG
TCAGGGTAGATTGTGCCTTGTGCTAACCATTTTACTGAAGTGAGTTTTTTCGACTCATCATCGAATACAT
CGACAAACACTTTACCGATGGTTTTACGTTTTGCTTCCGGTTCATCAATACCTTTTAACGCATCTAAGAA
ACGGTCTTCGGCATTTACACGAATGATATTTAAACCGAATTTATCGCCGAACATTTCCATCACTTGATCG
CCTTCGTTTAAACGAAGTAAACCGTTATCCACGAATACGCAGTGTAAGTTTTTGCCGATTGCACGATGTA
GAAGAAGTGCGGTTACTGATGAATCCACGCCGCCTGATAAACCTAAAATGACTTCGTCATCGCCTACTTG
CTCTTTAATACGAGCGACAGCGTCTTCGATAATATTTTCTGCCGTCCATTTACATTCGCAACCACAAATG
CCTACTACGAAGTTAGTTAATAACTCTAAACCGCTTTTCGTATGAGTTACTTCCGGGTGGAATTGCACAC
CGTAGAAACGACGGCTTTCGTCTGACATTGCTGCAATCGGGCAAGTTGGCGTTATACCTGTTACTTGGAA
ACCTTGCGGTAAACGAGTTACTTTATCGCCGTGGCTCATCCAAACGTCTAATTTCGGCTCGGAAGCGGTC
AAATTATCGTTTAATTTTGCAAATAACGCATCGGTCGCTTGTAAATCAACGGAAGCATAACCGAATTCAC
GATGATCAGAAGTTTCAGTTAAACCGCCTAATTGCATCGCCATGGTTTGCATACCATAGCAAATACCAAG
TACTGGCACGCCTGCGTTAAATACGTACTCCGGCGCACGAGGGCTGTTTTCTTCAGTGGTACTTTCAGGA
CCACCTGAAAGAATGATCCCGGTCGGGTTAAATTCACGGATTTGTTCTTCGGTGACATCCCACGCCCAAA
GCTCGCAATAAACCCCAATCTCACGCACACGACGTGCGATTAATTGCGTGTATTGTGAACCGAAGTCCAA
AATTAAAATTTTATGATTGTGAATGTTGGTCA
Protein Sequence 
>gi|165976006|ref|YP_001651599.1| GMP synthase [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAPEYVFNAGVPVLGICYGMQTMAMQLGGLTETSDHREFGYASVDLQATDALFAKLNDNLTASEPKLDVWMSHGDKVTRLPQGFQVTGITPTCPIAAMSDESRRFYGVQFHPEVTHTKSGLELLTNFVVGICGCECKWTAENIIEDAVARIKEQVGDDEVILGLSGGVDSSVTALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPEAKRKTIGKVFVDVFDDESKKLTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHPFPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELYKADWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: guaA mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0519F, under F: Nucleotide transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].