| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
UL41 |
Suid herpesvirus 1 |
2952522
|
|
51557510
|
SuHV1_gp27 |
S57917 |
YP_068344 |
tegument host shutoff protein |
Virulence factor |
MUTATION: A UL41 mutant is highly attenuated in mice [Ref7032:Lin et al., 2010].
|
20448414
|
|
|
UL8.5 (gp50) |
Suid herpesvirus 1 |
2952548
|
|
51557533
|
SuHV1_gp50 |
BK001744 |
YP_068367 |
|
Virulence factor |
MUTATION: A gp50 null mutant is attenuated in pigs [Ref7406:Peeters et al., 1994]. |
8178562
|
|
|
IE180 (gp63) |
Suid herpesvirus 1 |
2952540
|
|
51557548
|
SuHV1_gp63 |
BK001744 |
YP_068382 |
transcriptional regulator ICP4 |
Virulence factor |
MUTATION: A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated in pigs [Ref7406:Peeters et al., 1994]. |
8178562
|
|
|
glycoprotein E |
Suid herpesvirus 1 |
|
|
307634504
|
|
|
|
glycoprotein E |
Virulence factor |
MUTATION: gE mutant had strongly reduced virulence in pigs compared to wild-type PRV [Ref7410:Kimman et al., 1994].
MUTATION: A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. |
7975253
12488067
|
|
|
glycoprotein G |
Suid herpesvirus 1 |
|
|
15422177
|
|
|
|
glycoprotein G |
Virulence factor |
MUTATION: A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. |
12488067
|
|
|
glycoprotein M |
Suid herpesvirus 1 strain Kaplan |
|
|
1478255
|
|
|
|
UL10 |
Virulence factor |
MUTATION: A glycoprotein M, gM, deletion in pseudorabies virus was attenuated in piglets [Ref7408:Dijkstra et al., 1997]. |
9292000
|
|
|
UL23 |
Suid herpesvirus 1 |
2952559
|
|
51557518
|
SuHV1_gp35 |
BK001744 |
YP_068352 |
thymidine kinase |
Virulence factor |
MUTATION: a thymidine kinase PRV mutant is attenuated in pigs [Ref7410:Kimman et al., 1994].
MUTATION: A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. |
7975253
12488067
|
|
|
UL50 |
Suid herpesvirus 1 |
2952537
|
|
51557490
|
SuHV1_gp07 |
BK001744 |
YP_068324 |
deoxyuridine triphosphatase |
Virulence factor |
MUTATION: A UL50 mutant is attenuated in pigs [Ref7409:Jöns et al., 1997]. |
9228681
|
|
|
US3 |
Suid herpesvirus 1 |
2952561
|
|
126802155
|
SuHV1_gp65 |
BK001744 |
YP_068384 |
serine/threonine protein kinase US3 |
Virulence factor |
MUTATION: US3 mutant is attenuated in pigs [Ref7410:Kimman et al., 1994]. |
7975253
|
|
|
UL21 |
Suid herpesvirus 1 |
2952541
|
|
51557520
|
SuHV1_gp37 |
BK001744 |
YP_068354 |
tegument protein UL21 |
Virulence factor |
Mutant UL21 was constructed by insertion of an oligonucleotide that contains stop codons, In two PRV mutants carrying the oligonucleotide at two sites within UL21, processing of newly replicated viral DNA was impaired. The results show that one of the UL21 mutants has strongly reduced virulence for mice. [Ref7429:de et al., 1992]
|
1331512
|
|
|
US8 |
Suid herpesvirus 1 |
2952517
|
|
51557555
|
SuHV1_gp70 |
AY368490 |
YP_068389 |
envelope glycoprotein E |
Virulence factor |
Pigs immunized with M30, lacked amino acids valine (125) and cysteine(126) in an immunodominant antigenic region of glycoprotein I, were completely protected against challenge infection; no clinical signs of disease were detected, no virus was shed, and no secondary antibody response was detected. [Ref7436:Jacobs et al., 1993] |
8409943
|
|
|
US9 |
Suid herpesvirus 1 |
2952552
|
|
51557556
|
SuHV1_gp71 |
JF797219 |
YP_068390 |
membrane protein US9 |
Virulence factor |
Viruses with Us9 deleted have no observable defects in tissue culture yet have reduced virulence and restricted spread to retinorecipient neurons in the rodent brain.
[Ref7479:Brideau et al., 2000] |
10775591
|
