Protegen ID	Gene Name	Sequence Strain (Species/Organism)	NCBI Gene ID	NCBI Nucleotide GI	NCBI Protein GI	Locus Tag	Genbank Accession	Protein Accession	Protein Name	Protein Annotation	Molecule Role	Molecule Role Annotation	COG	PMID
4525	UL41	Suid herpesvirus 1	2952522		51557510	SuHV1_gp27	S57917	YP_068344	tegument host shutoff protein		Virulence factor	MUTATION: A UL41 mutant is highly attenuated in mice [Ref7032:Lin et al., 2010].; 		20448414
4992	UL8.5 (gp50)	Suid herpesvirus 1	2952548		51557533	SuHV1_gp50	BK001744	YP_068367			Virulence factor	MUTATION: A gp50 null mutant is attenuated in pigs [Ref7406:Peeters et al., 1994].		8178562
4993	IE180 (gp63)	Suid herpesvirus 1	2952540		51557548	SuHV1_gp63	BK001744	YP_068382	transcriptional regulator ICP4		Virulence factor	MUTATION: A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated in pigs [Ref7406:Peeters et al., 1994]. 		8178562
4994	glycoprotein E 	Suid herpesvirus 1 			307634504				glycoprotein E		Virulence factor	MUTATION: gE mutant had strongly reduced virulence in pigs compared to wild-type PRV [Ref7410:Kimman et al., 1994].; MUTATION: A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. 		7975253, 12488067
4995	glycoprotein G 	Suid herpesvirus 1 			15422177				glycoprotein G		Virulence factor	MUTATION: A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. 		12488067
4996	glycoprotein M 	Suid herpesvirus 1 strain Kaplan			1478255				UL10		Virulence factor	MUTATION: A glycoprotein M, gM, deletion in pseudorabies virus was attenuated in piglets [Ref7408:Dijkstra et al., 1997]. 		9292000
4997	UL23	Suid herpesvirus 1	2952559		51557518	SuHV1_gp35	BK001744	YP_068352	thymidine kinase		Virulence factor	MUTATION: a thymidine kinase PRV mutant is attenuated in pigs [Ref7410:Kimman et al., 1994]. ; MUTATION: A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons [Ref7407:Weigel et al., 2003]. 		7975253, 12488067
4998	UL50	Suid herpesvirus 1	2952537		51557490	SuHV1_gp07	BK001744	YP_068324	deoxyuridine triphosphatase		Virulence factor	MUTATION: A UL50 mutant is attenuated in pigs [Ref7409:Jöns et al., 1997].		9228681
4999	US3	Suid herpesvirus 1	2952561		126802155	SuHV1_gp65	BK001744	YP_068384	serine/threonine protein kinase US3		Virulence factor	MUTATION: US3 mutant is attenuated in pigs [Ref7410:Kimman et al., 1994]. 		7975253
5025	UL21	Suid herpesvirus 1	2952541		51557520	SuHV1_gp37	BK001744	YP_068354	tegument protein UL21		Virulence factor	Mutant UL21 was constructed by insertion of an oligonucleotide that contains stop codons, In two PRV mutants carrying the oligonucleotide at two sites within UL21, processing of newly replicated viral DNA was impaired. The results show that one of the UL21 mutants has strongly reduced virulence for mice. [Ref7429:de et al., 1992]; 		1331512
5032	US8	Suid herpesvirus 1	2952517		51557555	SuHV1_gp70	AY368490	YP_068389	envelope glycoprotein E		Virulence factor	Pigs immunized with M30, lacked amino acids valine (125) and cysteine(126) in an immunodominant antigenic region of glycoprotein I, were completely protected against challenge infection; no clinical signs of disease were detected, no virus was shed, and no secondary antibody response was detected.  [Ref7436:Jacobs et al., 1993]		8409943
5077	US9	Suid herpesvirus 1	2952552		51557556	SuHV1_gp71	JF797219	YP_068390	membrane protein US9		Virulence factor	Viruses with Us9 deleted have no observable defects in tissue culture yet have reduced virulence and restricted spread to retinorecipient neurons in the rodent brain.; [Ref7479:Brideau et al., 2000]		10775591