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US9

Victor ID 5077
Gene Name US9
Sequence Strain (Species/Organism) Suid herpesvirus 1
NCBI Gene ID 2952552
NCBI Protein GI 51557556
Locus Tag SuHV1_gp71
Genbank Accession JF797219
Protein Accession YP_068390
Taxonomy ID 10345
Gene Starting Position 125230
Gene Ending Position 125731
Gene Strand (Orientation) +
Protein Name membrane protein US9
Protein pI 9.45
Protein Weight 9927.44
Protein Length 98
Protein Note upstream ATG initiation codon is functional if predicted initiation codon is mutated
DNA Sequence 
>gi|51557483:125230-125731 Suid herpesvirus 1, complete genome
GCTTAAATACCGGGAGAACCGGCCCGCCCGCATTCCGACATGCCCGCCGCCGCCCCCGCCGACATGGACA
CGTTCGACCCCAGCGCCCCCGTCCCGACGAGCGTCTCTAACCCGGCCGCCGACGTCCTGCTGGCCCCCAA
GGGACCCCGCTCCCCGCTGCGCCCCCAGGACGACTCGGACTGCTACTACAGCGAGAGCGACAACGAGACG
CCCAGCGAGTTCCTGCGCCGCGTGGGACGCCGGCAGGCGGCGCGCCGGAGACGCCGCCGCTGCCTGATGG
GCGTCGCGATCAGCGCCGCCGCGCTGGTCATCTGCTCGCTGTCGGCGCTGATCGGGGGCATCATCGCCCG
GCACGTGTAGCGAGCGGGTGGTGGCCGCCCGCCCCGCCGCGCCCAGGAGGGGGGGTCCGGGGGGGCGAAG
CGGGCGGAGGAGAGCGAGCCACGTGGTTGTGGGCTCGGACTTGTCACAATAAATGGGCCCCGGCGCACCC
GGGCGCACACAG
Protein Sequence 
>gi|51557556|ref|YP_068390.1| membrane protein US9 [Suid herpesvirus 1]
MDTFDPSAPVPTSVSNPAADVLLAPKGPRSPLRPQDDSDCYYSESDNETPSEFLRRVGRRQAARRRRRRC
LMGVAISAAALVICSLSALIGGIIARHV
Molecule Role Virulence factor
Molecule Role Annotation Viruses with Us9 deleted have no observable defects in tissue culture yet have reduced virulence and restricted spread to retinorecipient neurons in the rodent brain.
(Brideau et al., 2000)
References
Brideau et al., 2000: Brideau AD, Eldridge MG, Enquist LW. Directional transneuronal infection by pseudorabies virus is dependent on an acidic internalization motif in the Us9 cytoplasmic tail. Journal of virology. 2000; 74(10); 4549-4561. [PubMed: 10775591].