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UL21

Victor ID 5025
Gene Name UL21
Sequence Strain (Species/Organism) Suid herpesvirus 1
NCBI Gene ID 2952541
NCBI Protein GI 51557520
Locus Tag SuHV1_gp37
Genbank Accession BK001744
Protein Accession YP_068354
Taxonomy ID 10345
Gene Starting Position 64487
Gene Ending Position 66125
Gene Strand (Orientation) -
Protein Name tegument protein UL21
Protein pI 5.66
Protein Weight 50273.48
Protein Length 525
DNA Sequence 
>gi|51557483:64487-66125 Suid herpesvirus 1, complete genome
GTTAACGGTTTTTATTGAGGACGATGGAGATGTTGGCGCGGGTCAGGCGCGCCCGAAACAGCTGAAACAG
GTACTGGGCCCCGCGGAGGGCCGCGGGCGAGTCGCCGAAGGCGGTCAGGAGCGCCGCCTCGGCGCAGACG
GCGGACGTGGGCCGCAGCGCGCGCCCCACGGGCGCCGTCGCGGCGACGAGGCCCCGGCCGGCGTAGAGCC
CGTCCAGCACCCGCGCCCCGGCCGCCTCCACCAGCTCGCACGCGTCGGCGTCCGGCGCGTTCGTCTCCGC
GTCGCTCATCATGACCGCCAGCTCCAGGCCCGTCGCCGCGTCCTCCCGGGCGTGCTTCGTCGTCGGCGGC
GAGGCCCCCGCCGGGTCCGCGATCGCGGGGGCGTGCACCACGGCGGCGTTCACGAGCATCCGCATCACCT
CGCCGAAGACGGTCGCCTCGCGCAGCACGCGGTTGACGGCGTGGGCCACGGCGCTCGCGGCCCGAGAGCC
GCCGTGGCCGCCCCCTCCTCCCCCTTCTCCTCCGTCGTCGTCGTCGTCGTCGCCCGCGCCCGCCCCGGGG
CGCTCGTCCAGCCTGTCGAGCATGCCCTCCAGCGCGGCGTAGCAGCTCGGCAGGTGCCAGCGGGCCAGGA
TGAACTGGTACAGCGCGAACCGCTGCGCGCCCGTGAGCGACGTGGAGCCCGTCCCGAAGAAGGGGTCCGC
CGCGACGGCGGACACGGCCTCGACCACGGCGGCCGAGGCGTCGTCCGAGGCGCCCGCGGCCCGCCGCAGG
ATGGCGTCCGCCCCGGCCACGAGGTCGCAGAGCATCTGCAGGGACAGGCTCCCGCCGCGCGTCGCCCAGA
TGCGCCGCGTCGCCGGGATGTAGCGCACCTGCACAAAGTCGCTGACCACCGTCGCGCGCAGCGCGCGCTC
GGCGTACCGGCGCGGGCGCACGCTCAGCGTGGGGGCCGCGCGCCCGCCCTTCACCACCACGGCCGTGGGC
CGCGTCTCGCCGCTGAGCGGGGGGCGCACGCCGGGGATGCCGTCAAAGAGCCCCTCCGTCAGCACCTGCA
GCGAGCTGGGCAGCTCGGAGAGGTACGCCTGCACCAGCGCGAAGCAGGCCTCGTTCACGGCGTACACGAA
GCCCGAGGAGGGGTGCACGATGGCGGGCTCGGCCAGGAGCTCCAGGACGCGGTCCTGCTGGCGGTCGTGC
ACGAGCGTCAGCGAGAGCGCCGACGCCGGCAGCGAGACCATGCACTCGACGAGGTAGGGGTCGTACACGT
CCAGCTCCGCGCGGCCGCAGAGGTCCAGCTCCGTCAGCGGCAGCAGCAGCCCCAGGGCGTCCACGAAGAC
GTCGTCGCTCCCCTGCGGGGCGGCCCACGCGCGGCCGAGGCGCGCCAGCTCCGTGCGCACGTAGTTGGCG
ACGACGCGGTTCCCGGGCGCGTTCCCGCGCAGCGTGAGCCCGAACTTGCCGATCTCCCGCGAGCGCCGGT
GCACGGACACGATGCAGCCCCCGTGCACAAAGTACGCGCGGTCCCCGCCGTCGGCGACGTAGAACAGCAC
CCCCTGGTGCACGATCGTGCTCTGGTACTCAAACTCCATGGCGGCGGGCACACGCGGCGCGGCAAATGGG
TGAGCGAGGCGGCGCGACCACTCCTTTAA
Protein Sequence 
>gi|51557520|ref|YP_068354.1| tegument protein UL21 [Suid herpesvirus 1]
MEFEYQSTIVHQGVLFYVADGGDRAYFVHGGCIVSVHRRSREIGKFGLTLRGNAPGNRVVANYVRTELAR
LGRAWAAPQGSDDVFVDALGLLLPLTELDLCGRAELDVYDPYLVECMVSLPASALSLTLVHDRQQDRVLE
LLAEPAIVHPSSGFVYAVNEACFALVQAYLSELPSSLQVLTEGLFDGIPGVRPPLSGETRPTAVVVKGGR
AAPTLSVRPRRYAERALRATVVSDFVQVRYIPATRRIWATRGGSLSLQMLCDLVAGADAILRRAAGASDD
ASAAVVEAVSAVAADPFFGTGSTSLTGAQRFALYQFILARWHLPSCYAALEGMLDRLDERPGAGAGDDDD
DDGGEGGGGGGHGGSRAASAVAHAVNRVLREATVFGEVMRMLVNAAVVHAPAIADPAGASPPTTKHARED
AATGLELAVMMSDAETNAPDADACELVEAAGARVLDGLYAGRGLVAATAPVGRALRPTSAVCAEAALLTA
FGDSPAALRGAQYLFQLFRARLTRANISIVLNKNR
Molecule Role Virulence factor
Molecule Role Annotation Mutant UL21 was constructed by insertion of an oligonucleotide that contains stop codons, In two PRV mutants carrying the oligonucleotide at two sites within UL21, processing of newly replicated viral DNA was impaired. The results show that one of the UL21 mutants has strongly reduced virulence for mice. (de et al., 1992)
References
de et al., 1992: de Wind N, Wagenaar F, Pol J, Kimman T, Berns A. The pseudorabies virus homology of the herpes simplex virus UL21 gene product is a capsid protein which is involved in capsid maturation. Journal of virology. 1992; 66(12); 7096-7103. [PubMed: 1331512].