Victors

US3
Victor ID	4999
Gene Name	US3
Sequence Strain (Species/Organism)	Suid herpesvirus 1
NCBI Gene ID	2952561
NCBI Protein GI	126802155
Locus Tag	SuHV1_gp65
Genbank Accession	BK001744
Protein Accession	YP_068384
Taxonomy ID	10345
Gene Starting Position	118238
Gene Ending Position	120955
Gene Strand (Orientation)	+
Protein Name	serine/threonine protein kinase US3
Protein pI	4.59
Protein Weight	34398.44
Protein Length	334
Protein Note	PK family
DNA Sequence	>gi\|51557483:118238-120955 Suid herpesvirus 1, complete genome AAATAAAGGAGTCCGGGGAATTTGTTCCTTATACCTTGCCGGGCTCAGCAGGGGGTTGTCGCGCGTCCAC GCCCAGCGCTCGCACGCAGCAACAATGGCCGACGCCGGAATCCCCGACGAGATCCTGTACTCGGACATCA GCGACGACGAGATCATCATCGACGGCGACGGCGACAGCAGCGGGGACGAGGACGACGATGACGGGGGGCT GACGCGGCAGGCCGCGGCGCGCATCGTCACGGACCTGGGCTTCGAGGTGCTGCAGCCCCTGCAGTCGGGC TCGGAGGGCCGCGTCTTCGTGGCCCGCCGGCCGGGCGAGGCGGACACGGTGGTGCTGAAGGTGGGCCAGA AGCCCTCGACGCTGATGGAGGGCATGCTGCTGCAGCGCCTGTCCCACGATAACGTCATGCGCATGAAACA GATGCTCGCCCGGGGCCCGGCGACGTGCCTGGTCCTGCCGCACTTTCGGTGCGATCTGTACAGCTACCTG ACCATGCGGGACGGGCCGCTGGACATGCGCGACGCCGGGTGCGTGATCCGGGCCGTGCTCCGCGGGCTCG CCTACCTGCACGGGATGCGCATCATGCATCGCGACGTCAAGGCGGAGAACATCTTCCTCGAGGACGTGGA CACGGTGTGCCTAGGGGACCTCGGGGCCGCGCGCTGCAACGTGGCGGCGCCCAACTTTTACGGGCTCGCC GGGACCATCGAGACCAACGCCCCCGAGGTGCTCGCGCGCGACCGCTACGACACCAAGGTCGACGTCTGGG GCGCGGGGGTGGTGCTCTTCGAGACGCTGGCCTACCCCAAGACGATCACCGGCGGGGACGAGCCCGCGAT CAACGGGGAGATGCACCTGATCGACCTCATCCGCGCCCTCGGGGTGCACCCCGAGGAGTTCCCGCCCGAC ACGCGCCTCCGGAGCGAGTTCGTCCGGTACGCCGGGACCCACCGCCAGCCGTACACGCAGTACGCGCGCG TGGCTCGCCTCGGGCTGCCCGAGACGGGGGCTTTCCTGATTTACAAGATGTTGACGTTTGATCCCGTCCG CCGCCCTTCCGCTGATGAGATACTCAACTTTGGAATGTGGACCGTATAAAACGGGCCGGCTCCGAGCGGT AGGACACACACACCTTTGCGCATCTCCACAGCTCAACAATGAAGTGGGCAACGTGGATCCTCGCCCTCGG GCTCCTCGTGGTCCGCACCGTCGTGGCCAGAGAGGCCCCTCGGGAGCTCTGCTACGGCCACCCCGTCCAC GACGACCGGCGGCCCGTCGGGCCCGCGACCGACGCCCAGCCCGTGAACCCGCTCGCCCCCGCCAACGCCA CCGGGACGGACTACTCTCGCGGCTGCGAGATGCGCCTCCTGGATCCGCCTCTCGACGTATCGTCCCGCTC CTCGGACCCCGTCAACGTGACCGTCGCCTGGTTCTTTGACGGCGGCCACTGCAAGGTGCCCCTCGTCCAC CGCGAGTACTACGGCTGCCCCGGGGACGCCATGCCCTCCGTCGAGACGTGCACCGGCGGGTACTCGTACA CCCGCACGCGCATCGACACCCTGATGGAGTACGCCCTCGTGAACGCCAGCCTCGTGCTGCAGCCCGGGCT GTACGACGCCGGCCTGTACATCGTCGTGCTCGTCTTTGGCGACGACGCCTACCTCGGCACCGTCTCCCTG TCGGTGGAGGCCAACCTGGACTACCCCTGCGGCATGAAGCACGGGCTCACGATCACCCGCCCCGGGGCCA CCCTCCCACCCATCGCCCCCACGGCCGGCGACCACCAGCGCTGGCGCGGGTGCTTCCCCTCGACCGACGA GGGCGCCTGGGAGAACGTGACCGCCGCCGAGAAGGGCCTGTCCGACGACTACGCCGACTACTACGACGTG CACATCTTCCGCTCGGAGTCTGACGACGAGGTCGTCCACGGCGATGCCCCCGAGGCCCCCGAGGGCGAGG AGGTGACCGAGGAGGAGGCCGAGCTGACCTCCAGCGACCTCGACAACATCGAGATCGAGGTCGTGGGCTC TCCCGCCGCTCCCGCCGAGGGCCCGGCGACGGAGGAGGGGCGCGGGGCCGAGGAGGACGAGGAGCTGACC TCCAGCGACCTCGACAACATCGAGATCGAGGTCGTGGGCTCGCCGCGGCCGCCCGCTTCTTCGCCGCCTC CACCACCCCCGCGCCCCCACCCGCGCGGCCGAGATCACGACCATGACCACGGTCACCACCGTGCGGACGA CCGAGGACCCCAGCGGCATCACCGACTGCCGCCGGAGCCGACCTTCGTCTCGCCCTCTGACATCTTCGTG ACCCCCACCGGCAGCCCCGCCCTGCTCCTGGGCTTCCTGGGCAGCGCGCTCGCCTCGCGCCCCCTGCACC TGACGGCCGGGGAGACGGCCCAGCACGTGCGCGAGGCCCAGCAGAAGAGCCGCCACATCCGCTCCCTCGG CGGCCTCCAGCTCTCGGTCGAGACCGAGACCACCAACACCACCACCACCCAGACGGGCCTGTCGGGCGAC ATCCGCACCTCGATCTACATCTGCGTCGCCCTCGCCGGCCTGGTCGTCGTGGGCATCGTCATCATGTGCC TCCATATGGCGATCATCAGGGCCCGGGCCCGGAACGACGGCTACCGCCACGTGGCCTCCGCCTGACCCGG CCCCGCCCGACTCCCCCGCGATTCCCCCCCTCTCTCACCGGGTGTCCATCTTCAATAA
Protein Sequence	>gi\|126802155\|ref\|YP_068384.2\| serine/threonine protein kinase US3 [Suid herpesvirus 1] MADAGIPDEILYSDISDDEIIIDGDGDSSGDEDDDDGGLTRQAAARIVTDLGFEVLQPLQSGSEGRVFVA RRPGEADTVVLKVGQKPSTLMEGMLLQRLSHDNVMRMKQMLARGPATCLVLPHFRCDLYSYLTMRDGPLD MRDAGCVIRAVLRGLAYLHGMRIMHRDVKAENIFLEDVDTVCLGDLGAARCNVAAPNFYGLAGTIETNAP EVLARDRYDTKVDVWGAGVVLFETLAYPKTITGGDEPAINGEMHLIDLIRALGVHPEEFPPDTRLRSEFV RYAGTHRQPYTQYARVARLGLPETGAFLIYKMLTFDPVRRPSADEILNFGMWTV
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: US3 mutant is attenuated in pigs (Kimman et al., 1994).
References	*Kimman et al., 1994:* Kimman TG, De Wind N, De Bruin T, de Visser Y, Voermans J. Inactivation of glycoprotein gE and thymidine kinase or the US3-encoded protein kinase synergistically decreases in vivo replication of pseudorabies virus and the induction of protective immunity. Virology. 1994; 205(2); 511-518. [PubMed: 7975253].


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US3