| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
ruvB |
Borrelia burgdorferi B31 |
1194858
|
|
15594368
|
BB0022 |
AE000783 |
NP_212156 |
Holliday junction DNA helicase RuvB |
Virulence factor |
MUTATION: mutant showed attenuated virulence in C3H/HeN mice [Ref6904:Lin et al., 2009]. |
19997622
|
|
|
ruvA |
Borrelia burgdorferi B31 |
1194859
|
|
15594369
|
BB0023 |
AE000783 |
NP_212157 |
Holliday junction DNA helicase RuvA |
Virulence factor |
MUTATION: mutant showed attenuated virulence in C3H/HeN mice [Ref6904:Lin et al., 2009]. |
19997622
|
|
|
BB0098 |
Borrelia burgdorferi B31 |
1194934
|
|
15594444
|
BB0098 |
AE000783 |
NP_212232 |
recombination and DNA strand exchange inhibitor protein |
Virulence factor |
MUTATION: mutant showed attenuated virulence in C3H/HeN mice [Ref6904:Lin et al., 2009]. |
19997622
|
|
|
BB0153 |
Borrelia burgdorferi B31 |
1194988
|
|
15594498
|
BB0153 |
AE000783 |
NP_212287 |
superoxide dismutase (sodA) |
Virulence factor |
MUTATION: sodA mutant showed complete attenuation in C3H/HeN mice compared with control strains [Ref6905:Esteve-Gassent et al., 2009]. |
19040638
|
|
|
BB0198 |
Borrelia burgdorferi B31 |
1195033
|
|
15594543
|
BB0198 |
AE000783 |
NP_212332 |
guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (spoT) |
Virulence factor |
MUTATION: rel(Bbu) deletion mutant eliminated virulence in mice [Ref6906:Bugrysheva et al., 2005]. |
16041012
|
|
|
BB0210 |
Borrelia burgdorferi B31 |
1195047
|
|
15594555
|
BB0210 |
AE000783 |
NP_212344 |
surface-located membrane protein 1 (lmp1) |
Virulence factor |
MUTATION: deletion severely impaired mutant's ability to persist and induce disease in murine tissues [Ref6907:Yang et al., 2009]. |
19266024
|
|
|
BB0219 |
Borrelia burgdorferi B31 |
1195056
|
|
15594564
|
BB0219 |
AE000783 |
NP_212353 |
gufA protein |
Virulence factor |
MUTATION: bmtA mutant attenuated in mice [Ref6908:Ouyang et al., 2009]. |
19218460
|
|
|
BB0268 |
Borrelia burgdorferi B31 |
1195105
|
|
15594613
|
BB0268 |
AE000783 |
NP_212402 |
hypothetical protein |
Virulence factor |
MUTATION: mutant not infectious in murine model [Ref6909:Lybecker et al., 2010]. |
20815822
|
|
|
BB0323 |
Borrelia burgdorferi B31 |
1195160
|
|
15594668
|
BB0323 |
AE000783 |
NP_212457 |
hypothetical protein |
Virulence factor |
MUTATION: deletion mutant unable to infect mice or ticks [Ref6910:Zhang et al., 2009] |
19754308
|
|
|
BB0363 |
Borrelia burgdorferi |
1195200
|
|
15594708
|
BB0363 |
|
NP_212497.1 |
periplasmic protein |
Virulence factor |
MUTATION: mutant not infectious in mice, showed decreased motility [Ref6911:Sultan et al., 2010]. |
20444101
|
|
|
BB0797 |
Borrelia burgdorferi B31 |
1195655
|
|
15595142
|
BB0797 |
AE000783 |
NP_212931 |
DNA mismatch repair protein MutS |
Virulence factor |
MUTATION: mutant showed attenuated virulence in C3H/HeN mice [Ref6904:Lin et al., 2009]. |
19997622
|
|
|
bosR |
Borrelia burgdorferi ZS7 |
7106930
|
|
218249450
|
BbuZS7_0667 |
CP001205 |
YP_002375148 |
oxidative stress regulator protein BosR |
Virulence factor |
MUTATION: BosR mutant attenuated in mice [Ref6990:Hyde et al., 2009]. |
19906179
|
|
|
cspA from Borrelia burgdorferi ZS7 |
Borrelia burgdorferi ZS7 |
7205433
|
|
219499160
|
BbuZS7_A59 |
|
YP_002455377.1 |
complement regulator-acquiring surface protein 1 (CRASP-1) |
Virulence factor |
MUTATION: mutant showed reduced ability to adhere to human PH cells [Ref6991:Kenedy et al., 2009]. |
19451251
|
|
|
dbpA from Borrelia burgdorferi ZS7 |
Borrelia burgdorferi ZS7 |
7205446
|
|
219499176
|
BbuZS7_A21 |
|
YP_002455347.1 |
decorin-binding protein A |
Virulence factor |
MUTATION: dbpA deletion mutant was unable to colonize heart tissue of mice [Ref6992:Shi et al., 2008]. |
18195034
|
|
|
bbk32 |
Borrelia burgdorferi 156a |
7279517
|
|
219873298
|
Bbu156a_K19 |
CP001260 |
YP_002477384 |
fibronectin-binding protein hypothetical protein |
Virulence factor |
MUTATION: bbk32 knockout was significantly attenuated in murine model [Ref6993:Seshu et al., 2006]. |
16468997
|
|
|
cspA from Borrelia burgdorferi 156a |
Borrelia burgdorferi 156a |
7265888
|
|
219807322
|
Bbu156a_A60 |
|
YP_002477614.1 |
complement regulator-acquiring surface protein 1 (CRASP-1) |
Virulence factor |
MUTATION: mutant showed reduced ability to adhere to human PH cells [Ref6991:Kenedy et al., 2009]. |
19451251
|
|
|
cspA from Borrelia burgdorferi N40 |
Borrelia burgdorferi N40 |
8319504
|
|
256055331
|
BbuN40_A68 |
|
YP_003110790.1 |
complement regulator acquiring protein 1; putative lipoprotein |
Virulence factor |
MUTATION: mutant showed reduced ability to adhere to human PH cells [Ref6991:Kenedy et al., 2009]. |
19451251
|
|
|
fla |
Borrelia burgdorferi HB19 |
|
|
435009
|
|
|
|
flagellin |
Virulence factor |
MUTATION: A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice [Ref7370:Sadziene et al., 1996]. |
8627071
|
