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ruvA

Victor ID 4191
Gene Name ruvA
Sequence Strain (Species/Organism) Borrelia burgdorferi B31
NCBI Gene ID 1194859
NCBI Protein GI 15594369
Locus Tag BB0023
Genbank Accession AE000783
Protein Accession NP_212157
Other Database IDs UniProtKB-ID: RUVA_BORBU
UniRef100: UniRef100_B7J0W2
UniRef90: UniRef90_B7J0W2
UniRef50: UniRef50_B7J0W2
UniParc: UPI0000057304
EMBL: Y08885
EMBL: AE000783
EMBL-CDS: CAA70096.1
EMBL-CDS: AAC66409.1
RefSeq_NT: NC_001318.1
EnsemblGenome: EBBORG00000008921
EnsemblGenome_TRS: EBBORT00000008922
EnsemblGenome_PRO: EBBORP00000008252
GenomeReviews: AE000783_GR
KEGG: bbu:BB0023
NMPDR: fig|224326.1.peg.407
TIGR: BB_0023
HOGENOM: HBG635309
OMA: SEREVFE
ProtClustDB: PRK13901
BioCyc: BBUR224326:BB_0023-MONOM
Taxonomy ID 224326
Gene Starting Position 22145
Gene Ending Position 22738
Gene Strand (Orientation) -
Protein Name Holliday junction DNA helicase RuvA
Protein pI 8.43
Protein Weight 21497.44
Protein Length 197
Protein Note plays an essential role in ATP-dependent branch migration of the Holliday junction
DNA Sequence 
>gi|15594346:22145-22738 Borrelia burgdorferi B31 chromosome, complete genome
ATTAATTCGATATTCTTTTTAAAACCTCCTTAAATAAAAACTGCTCCTTTTCAGAATCTTTTAAATTTGC
AAATTCAGCTAAATTGAAAGCCTCTCTAATCTTGCTATTAACAATTTTTCTATCAAATCCCATACTAACA
ATTGATTCTTCTAATTCTTTAAATCTAAAAAGACCAGTGGATTCAAGCTCGCTATTAATCAAAAGCTTAC
CTTGAAGATGTAAAAACATTTTACCAGCCATTTTTTTGCCAATGCCTTTGATTTTAGAGACAAGTTCAAT
ATCCTCTTTGTCAATAGCCTCCTTAAACTCATTATACCTTATATTGGATAACACTCTTAAAGCGGCCCTT
GGGCCTACTCCGCTTACTCCAATAAGCTCCTTAAAGATCTCTCTTTCATCTGAATTCAAAAATCCAAAAA
GTTTTAATTCATTTTCTCTAGTATAAAGATAAGTAAATAACTCAACTTTGTCTGACAAATTAAAATTAGC
AAGGCAAAATGCACTAACTAAAAGTTCAAATTCAAAAACAGTAGTCATTAAAACTAAACTAGATTCTTTT
TTTTCTATAACTTTACCATGAATCTTATTTATCA
Protein Sequence 
>gi|15594369|ref|NP_212157.1| Holliday junction DNA helicase RuvA [Borrelia burgdorferi B31]
MINKIHGKVIEKKESSLVLMTTVFEFELLVSAFCLANFNLSDKVELFTYLYTRENELKLFGFLNSDEREI
FKELIGVSGVGPRAALRVLSNIRYNEFKEAIDKEDIELVSKIKGIGKKMAGKMFLHLQGKLLINSELEST
GLFRFKELEESIVSMGFDRKIVNSKIREAFNLAEFANLKDSEKEQFLFKEVLKRISN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant showed attenuated virulence in C3H/HeN mice (Lin et al., 2009).
COG COG0632L, under L: Replication, recombination and repair
References
Lin et al., 2009: Lin T, Gao L, Edmondson DG, Jacobs MB, Philipp MT, Norris SJ. Central role of the Holliday junction helicase RuvAB in vlsE recombination and infectivity of Borrelia burgdorferi. PLoS pathogens. 2009; 5(12); e1000679. [PubMed: 19997622].