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bbk32

Victor ID 4452
Gene Name bbk32
Sequence Strain (Species/Organism) Borrelia burgdorferi 156a
NCBI Gene ID 7279517
NCBI Protein GI 219873298
Locus Tag Bbu156a_K19
Genbank Accession CP001260
Protein Accession YP_002477384
Other Database IDs UniProtKB-ID: B8EGL2_BORBU
UniRef100: UniRef100_B8EGL2
UniRef90: UniRef90_Q8RJ09
UniRef50: UniRef50_C5J484
UniParc: UPI00016B3A35
EMBL: CP001260
EMBL-CDS: ACL33888.1
RefSeq_NT: NC_011870.1
ProtClustDB: CLSK541165
Taxonomy ID 445983
Plasmid No 156a_lp36
Gene Starting Position 15597
Gene Ending Position 16679
Gene Strand (Orientation) +
Protein Name fibronectin-binding protein hypothetical protein
Protein pI 4.98
Protein Weight 40490.87
Protein Length 360
DNA Sequence 
>gi|219873279:15597-16679 Borrelia burgdorferi 156a plasmid 156a_lp36, complete sequence
CATGAAAAAAGTTAAAAGTAAATATTTGGCTTTGGGATTACTTTTTGGTTTTATAAGTTGTGATTTATTC
ATAAGATATGAAATGAAAGAGGAATCCCCTGGCTTATTTGATAAGGGAAACTCTATTTTAGAGACTAGCG
AGGAATCTATTAAAAAGCCTATGAATAAGAAAGGTAAAGGTAAGATTGCTAGAAAGAAAGGCAAAAGCAA
GGTTTCTAGAAAAGAACCGTATATTCATAGTTTAAAAAGGGACTCTGCTAATAAAAGCAATTTTTTACAA
AAAAATGTAATTTTAGAGGAAGAAAGTTTAAAAACTGAATTATTAAAAGAGCAATCTGAGACTAGAAAAG
AAAAAATACAAAAACAACAAGATGAATATAAAGGGATGACTCAAGGAAGTTTAAATTCCCTTAGCGGTGA
AAGTGGTGAATTGGAGGAGCCTATTGAAAGTAATGAAATTGATCTTACTATAGATTCTGATTTAAGGCCA
AAGAGTTCCTTACAAGGCATTGCAGGATCAAACTCTATTTCATACACTGATGAAATAGAGGAAGAGGATT
ATGATCGGTATTATTTAGATGAATATGATGAAGAGGATGAAGAGGATGAAGAGGATGAAGAGGAAATAAG
ATTAAGCAATCGATATCAATCTTATCTAGAAGGTGTTAAATATAATGTAGATTCAGCAATTCAAACAATT
ACTAAGATATATAATACTTATATATTATTTTCAACAAAGCTAACCCAAATGTATTCTACACGCCTTGACA
ACTTTGCTAAAGCCAAAGCTAAAGAAGAAGCTGCAAAGTTTACAAAAGAAGACCTTGAAAAAAATTTCAA
GACCTTATTAAATTATATTCAAGTAAGTGTAAAGACTGCAGCAAATTTTGTATACATAAATGACACGCAT
GCAAAAAGGAAATTAGAGAACATTGAAGCAGAAATAAAAACTTTAATTGCAAAGATCAAAGAACAATCTA
ATTTATACGAAGCATATAAAGCAATAGTAACGTCAATCTTATTAATGAGGGATTCTCTTAAAGAAGTGCA
AGGTATCATTGACAAGAATGGCGTTTGGTACTA
Protein Sequence 
>gi|219873298|ref|YP_002477384.1| fibronectin-binding protein hypothetical protein [Borrelia burgdorferi 156a]
MKKVKSKYLALGLLFGFISCDLFIRYEMKEESPGLFDKGNSILETSEESIKKPMNKKGKGKIARKKGKSK
VSRKEPYIHSLKRDSANKSNFLQKNVILEEESLKTELLKEQSETRKEKIQKQQDEYKGMTQGSLNSLSGE
SGELEEPIESNEIDLTIDSDLRPKSSLQGIAGSNSISYTDEIEEEDYDRYYLDEYDEEDEEDEEDEEEIR
LSNRYQSYLEGVKYNVDSAIQTITKIYNTYILFSTKLTQMYSTRLDNFAKAKAKEEAAKFTKEDLEKNFK
TLLNYIQVSVKTAANFVYINDTHAKRKLENIEAEIKTLIAKIKEQSNLYEAYKAIVTSILLMRDSLKEVQ
GIIDKNGVWY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bbk32 knockout was significantly attenuated in murine model (Seshu et al., 2006).
References
Seshu et al., 2006: Seshu J, Esteve-Gassent MD, Labandeira-Rey M, Kim JH, Trzeciakowski JP, Höök M, Skare JT. Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi. Molecular microbiology. 2006; 59(5); 1591-1601. [PubMed: 16468997].