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BB0219

Victor ID 4196
Gene Name BB0219
Sequence Strain (Species/Organism) Borrelia burgdorferi B31
NCBI Gene ID 1195056
NCBI Protein GI 15594564
Locus Tag BB0219
Genbank Accession AE000783
Protein Accession NP_212353
Other Database IDs UniProtKB-ID: O51237_BORBU
UniRef100: UniRef100_B7J1E9
UniRef90: UniRef90_B7J1E9
UniRef50: UniRef50_A1QZ13
UniParc: UPI00000573C5
EMBL: AE000783
EMBL-CDS: AAC66605.1
RefSeq_NT: NC_001318.1
EnsemblGenome: EBBORG00000008426.
EnsemblGenome_TRS: EBBORT00000008427
EnsemblGenome_PRO: EBBORP00000007757
GenomeReviews: AE000783_GR
KEGG: bbu:BB0219
NMPDR: fig|224326.1.peg.603
TIGR: BB_0219
HOGENOM: HBG620552
OMA: AVTIHNI
ProtClustDB: CLSK507445
BioCyc: BBUR224326:BB_0219-MONOMER
Taxonomy ID 224326
Gene Starting Position 223963
Gene Ending Position 224784
Gene Strand (Orientation) -
Protein Name gufA protein
Protein pI 4.98
Protein Weight 27465.34
Protein Length 273
Protein Note similar to SP:Q06916 GB:X71062 PID:49253 PID:861060 percent identity: 34.13; identified by sequence similarity; putative
DNA Sequence 
>gi|15594346:223963-224784 Borrelia burgdorferi B31 chromosome, complete genome
TTTAACCTAGTGAAACATCGAGAAACATCATTAATGTAAAACCAATAACACCAAATATACTTGGCACTTT
ATTGTCAATGTCTTTTCTCTTAGCTTCAGGTATTAATTGTTCAATTGACACATAAATCATAGCTCCTGCA
GAAAAAGCCAAAGCAAAAGGTAAAATTCGAGTAAAAGAATAAACCGCATAAGCACCCATAAGCCCCCCCA
CAATTTCTACCAATCCTGACATTTGGCCATAGTTAAAGCATTTTGCCAAAGCAACATTACCTCTTCTTAA
AGGCAGAGAAATAGCTGCTCCTTCGGGAATATTTTGAATACCAATACCAAGCGTAAGAAGCATAGCCCCA
ACTAAAGTTTGAATATCTGGATTAGACGCCAAGGCTCCAAAAGCAACTCCAACAGCCAATCCTTCTGGAA
AATTATGTAAAGTAACAGCAGTAAAGAGTAAAAAATCTTTTTTACCATGTTTAGTTAAGTCTTCATCAAT
AAAAGTAAGTTTATCCAGATCTGGAACAAATACATCTACAATATATATAAAAAATGCCCCAACAAGAAAT
CCAAAAACAGCCGGCACCCAAGTAATGTATCCAAGCTCTTCAGCTCTTTCTATAGCAGGCTGAATAAGCG
AAAAAAAACTGGCCGCTATCATAATGCCAGCTGAAAAACCAAGCATAGCGTCCATTATTTTATTATCTAC
CTTTCTAAAGAAAAAAACTGCTGCTGCTCCAAAAGCTGTAGTAAACCAAGTGAAAGTAGAACCTAAAAGT
CCCAATAATACAGGATGCAAAGTTAATAAATAATCTAAAATTGATTTTATCA
Protein Sequence 
>gi|15594564|ref|NP_212353.1| gufA protein [Borrelia burgdorferi B31]
MIKSILDYLLTLHPVLLGLLGSTFTWFTTAFGAAAVFFFRKVDNKIMDAMLGFSAGIMIAASFFSLIQPA
IERAEELGYITWVPAVFGFLVGAFFIYIVDVFVPDLDKLTFIDEDLTKHGKKDFLLFTAVTLHNFPEGLA
VGVAFGALASNPDIQTLVGAMLLTLGIGIQNIPEGAAISLPLRRGNVALAKCFNYGQMSGLVEIVGGLMG
AYAVYSFTRILPFALAFSAGAMIYVSIEQLIPEAKRKDIDNKVPSIFGVIGFTLMMFLDVSLG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bmtA mutant attenuated in mice (Ouyang et al., 2009).
COG COG0428P, under P: Inorganic ion transport and metabolism
References
Ouyang et al., 2009: Ouyang Z, He M, Oman T, Yang XF, Norgard MV. A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi. Proceedings of the National Academy of Sciences of the United States of America. 2009; 106(9); 3449-3454. [PubMed: 19218460].