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cspA from Borrelia burgdorferi ZS7

Victor ID 4450
Gene Name cspA from Borrelia burgdorferi ZS7
Sequence Strain (Species/Organism) Borrelia burgdorferi ZS7
NCBI Gene ID 7205433
NCBI Protein GI 219499160
Locus Tag BbuZS7_A59
Protein Accession YP_002455377.1
Other Database IDs UniProtKB-ID: B7IZX9_BORBZ
UniRef100: UniRef100_B7IZX9
UniRef90: UniRef90_B7IZX9
UniRef50: UniRef50_B7IZX9
UniParc: UPI00016B363E
EMBL: CP001199
EMBL-CDS: ACK74237.1
RefSeq_NT: NC_011784.1
EnsemblGenome: EBBORG00000002360.
EnsemblGenome_TRS: EBBORT00000002360
EnsemblGenome_PRO: EBBORP00000002146
GenomeReviews: CP001199_GR
KEGG: bbz:BbuZS7_A59
HOGENOM: HBG353192
OMA: ANANTKP
ProtClustDB: CLSK2392764
Taxonomy ID 445985
Plasmid No ZS7_lp54
Gene Starting Position 46449
Gene Ending Position 47204
Gene Strand (Orientation) -
Protein Name complement regulator-acquiring surface protein 1 (CRASP-1)
DNA Sequence 
>gi|219499124:46449-47204 Borrelia burgdorferi ZS7 plasmid ZS7_lp54, complete sequence
ATTAGTAAAAGGCAGGTTTTAAAGTATCAAAATCTTTGTAATATTTATTAAAGTGTTCTGCCAGTATTTT
CTCATTATCTTGAGTATTTTGATTGTAAACTTTAAGAGTTTCGTTTAAGGTTTTTTTAAGTCTTTGTTTT
ATCTCTAAGTTGGATTTTATTTGCATTAGCAATGATTTAGATTCTTCTTGACTTAGATTTTCTACTCCAT
TTTGTATTAATTCTAAATTTTGCTCTATTTGGAATTGAATGCTCCATGATATGTGATAAATCAATCTTCC
AATTATATTGTAATGTTTGGAATTTTTTTTAAGTATTTCAAGAATTTCTTTTAATTTTTCTATATTTTCT
TTTTTATAATCTAAAGATGAGTAAAGCGTTCTTTTTATTTTCATTTGGATATCTTCATCAATAAGATCGT
AAGGACCAACTTTAAAAGTGCTTAGGAAATCAAATTTTTCCTTAGCAATTTTAGCTATTTGTATATTTTC
TTCTTTTTTTTGATCTTCCAGTTCCTTACCAATTGCTTTTAGCTCTGAAGCGATAGTTTCCATAATTTTT
TCATCAGAAGCGCTAAGGTCTCCAGATTTATCTTCAAAATTTTGGGTGTTTTCCCCCGGATTGGTGATTT
TTTTTGGCTTAGTGTTTGCATTTGCTTTAGGATCGATTTTGCTAAAAGGTGCGCATGAGGTGCAAATTAA
AGTTAATATCATTGCAATAATATTAAGCTTGATTATATTTAGTTTGGCTTTTGTCA
Protein Sequence 
>gi|219499160|ref|YP_002455377.1| complement regulator-acquiring surface protein 1 (CRASP-1) [Borrelia burgdorferi ZS7] MTKAKLNIIKLNIIAMILTLICTSCAPFSKIDPKANANTKPKKITNPGENTQNFEDKSGDLSASDEKIMETIASELKAIGKELEDQKKEENIQIAKIAKEKFDFLSTFKVGPYDLIDEDIQMKIKRTLYSSLDYKKENIEKLKEILEILKKNSKHYNIIGRLIYHISWSIQFQIEQNLELIQNGVENLSQEESKSLLMQIKSNLEIKQRLKKTLNETLKVYNQNTQDNEKILAEHFNKYYKDFDTLKPAFY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant showed reduced ability to adhere to human PH cells (Kenedy et al., 2009).
References
Kenedy et al., 2009: Kenedy MR, Vuppala SR, Siegel C, Kraiczy P, Akins DR. CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infection and immunity. 2009; 77(7); 2773-2782. [PubMed: 19451251].