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BB0198

Victor ID 4194
Gene Name BB0198
Sequence Strain (Species/Organism) Borrelia burgdorferi B31
NCBI Gene ID 1195033
NCBI Protein GI 15594543
Locus Tag BB0198
Genbank Accession AE000783
Protein Accession NP_212332
Other Database IDs UniProtKB-ID: SPOT_BORBU
UniRef100: UniRef100_O51216
UniRef90: UniRef90_O51216
UniRef50: UniRef50_O51216
UniParc: UPI0000004A1F
EMBL: AE000783
EMBL-CDS: AAC66590.1
RefSeq_NT: NC_001318.1
EnsemblGenome: EBBORG00000008908
EnsemblGenome_TRS: EBBORT00000008909
EnsemblGenome_PRO: EBBORP00000008239
GenomeReviews: AE000783_GR
KEGG: bbu:BB0198
TIGR: BB_0198
HOGENOM: HBG594146
OMA: EPETFRK
ProtClustDB: CLSK507424
BioCyc: BBUR224326:BB_0198-MONOMER
Taxonomy ID 224326
Gene Starting Position 195692
Gene Ending Position 197695
Gene Strand (Orientation) +
Protein Name guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (spoT)
Protein pI 8.96
Protein Weight 75279.53
Protein Length 667
Protein Note similar to GB:L10328 SP:P17580 GB:M24503 PID:290500 PID:551840 percent identity: 38.99; identified by sequence similarity; putative
DNA Sequence 
>gi|15594346:195692-197695 Borrelia burgdorferi B31 chromosome, complete genome
GATGATACAAGCATACGAAATTGCACATTTAATCAAGATAAATGATCTTGAAAAAGCTAGAAATATTTTT
AAAAAAACTGTTGAAAATACTTACAAAGATGAATTTGAACGAAAAAGCATATTCAAAGCTCTAGAAATAG
CAGAACAGCTCCACTATGGCCAATATAGAGAAAGTGGAGAGCCTTACATTATTCACCCAATAATGGTTTC
ATTATTTCTTGCCAAATTTCAACTAGATTTTAAAGCAACTATTGCTGGACTACTGCATGACGTACTTGAA
GATACAAATGTTGAAAAAGAAGAAATAGTAAAAGAATTTGACGAGGAAATTTTAAGCCTAATCGACGGTG
TAACTAAAATTCATGATTTACACAATAAAACAAGAAGCATAAAAGAGGCTAATACTATCTCAAAAATGTT
TTTTGCAATGACACATGATATTAGAATAATAATAATAAAACTGGCAGATAAACTTCATAATATGACAACT
CTCTCTTATTTGCCCAAAAACAGACAAGACAGGATTGCAAAAGATTGCCTTTCAACTTACGTTCCAATAG
CAGAACGCCTTGGGATCTCATCTCTTAAAACATATCTTGAGGATCTTTCATTTAAGCATCTTTATCCTAA
AGATTATAAAGAAATAAAAAATTTTTTATCTGAAACAAAAATAGAAAGAGAAAAAAAATTATACAAAGGA
AAATTATCAATAGAAAAAGAACTTCAAAAAAGCGGAATTGAAGCAGAAATTACAGTAAGATCAAAACACT
TTTATTCAATATTTAGAAAAATGCAAACAAGAACAAACAAACTTACTCAAATTTTTGATACTCTAGGAAT
AAGAATAATTTGCAAAAAACAAAAAGAATGTTATGAGATATTAGAAATTGTTCACCGGGTGTGGAAACCA
ATCCCGGGAAGACTTAAAGACTATATTGCAAGCCCAAAAGAAAATAAATATCAATCACTACACACTACTG
TAAGAATACCTGAGGATAACCAGCTTATTGAAATACAAATTCGAACAGAAGAAATGGATAGAATTGCCAA
TTATGGGGTTGCAGCCCACTGGATATATAAAGAACAAATTGAACTTAAAGCTGATGATCTTTCATTTATA
AACCGAATAAAAAAATGGCAACAAGAATCGGCCAACAAAAGTCAATATTCAATGAATGACATACACAAAG
AGTTGTTGAATACATTCATATATGTTTACACCCCAGAAGGAGAAGTAGTAGAACTTCCTTTTGGATCAAA
TTCAATTGATTTTGCATACATAATTCACACAGATATTGGAGATCAAGCTCTTTATGCAAAAATAAACGGA
AAAATAAGCTCAATCACAAAACCGCTTAAAAACGAACAAATTGTTGAAATATTCACATCAAAAGACTCAA
AACCGGATGTAATATGGCTAAACAGCGTAAGAACAAAAAAGGCCCGATCAAAAATTAGATCATGGCTTAA
CAAGAATGACAACACAATTTTTGTAGACAACAATATTATTGCTTATCTTGTTGGAGCAAACAAAGAGCAA
AGAAAGCTTTTCAGCTTATTCAAATCTTATACCAAAACCAAAATAAAAAGAATTGCAATAGACCCTGAAT
GTAGTCCAACAACAGGTGAAGATATTATTGGAATAATACATAAAGACGAAATAATAGTGCACAATGAAAA
TTGTCAAAAGCTTAAATCCTATAAAAAACCCCAATTGATTGAAGTTGAGTGGGAAGCAACACCAACTAGA
AAAGTGCATCACATTATTTTACTTTTAAAAGAGCTTAAAGGAATATTTAGCTATCTTGAAAACATTTTCA
CACTCAATGACGTAAGACTTATTAGCGAAAAAATAGAAGACTGCGGAAATGGTCATGGAATAACAAATAT
AATAGTCTCATCAAATGCTAAAAATATAACAAAAATTATTTCTGCTTTAAAAGAAAACCCAAATATCTTA
CAAATAATGCAAATAGAAGAAGACATTAAAAATTATGACAATTA
Protein Sequence 
>gi|15594543|ref|NP_212332.1| guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (spoT) [Borrelia burgdorferi B31]
MIQAYEIAHLIKINDLEKARNIFKKTVENTYKDEFERKSIFKALEIAEQLHYGQYRESGEPYIIHPIMVS
LFLAKFQLDFKATIAGLLHDVLEDTNVEKEEIVKEFDEEILSLIDGVTKIHDLHNKTRSIKEANTISKMF
FAMTHDIRIIIIKLADKLHNMTTLSYLPKNRQDRIAKDCLSTYVPIAERLGISSLKTYLEDLSFKHLYPK
DYKEIKNFLSETKIEREKKLYKGKLSIEKELQKSGIEAEITVRSKHFYSIFRKMQTRTNKLTQIFDTLGI
RIICKKQKECYEILEIVHRVWKPIPGRLKDYIASPKENKYQSLHTTVRIPEDNQLIEIQIRTEEMDRIAN
YGVAAHWIYKEQIELKADDLSFINRIKKWQQESANKSQYSMNDIHKELLNTFIYVYTPEGEVVELPFGSN
SIDFAYIIHTDIGDQALYAKINGKISSITKPLKNEQIVEIFTSKDSKPDVIWLNSVRTKKARSKIRSWLN
KNDNTIFVDNNIIAYLVGANKEQRKLFSLFKSYTKTKIKRIAIDPECSPTTGEDIIGIIHKDEIIVHNEN
CQKLKSYKKPQLIEVEWEATPTRKVHHIILLLKELKGIFSYLENIFTLNDVRLISEKIEDCGNGHGITNI
IVSSNAKNITKIISALKENPNILQIMQIEEDIKNYDN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rel(Bbu) deletion mutant eliminated virulence in mice (Bugrysheva et al., 2005).
COG COG0317TK, under T: Signal transduction mechanisms; K: Transcription
References
Bugrysheva et al., 2005: Bugrysheva JV, Bryksin AV, Godfrey HP, Cabello FC. Borrelia burgdorferi rel is responsible for generation of guanosine-3'-diphosphate-5'-triphosphate and growth control. Infection and immunity. 2005; 73(8); 4972-4981. [PubMed: 16041012].