| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
groEL |
Bartonella bacilliformis KC583 |
4683978
|
|
121602875
|
BARBAKC583_1172 |
CP000524 |
YP_989430 |
chaperonin GroEL |
Virulence factor |
MUTATION: LSS100, a strain that synthesizes markedly greater quantities of GroEL relative to others, significantly accelerates apoptosis of the cocultured HUVECs relative to other strains [Ref7072:Smitherman and Minnick, 2005].
|
16481529
|
|
|
ialB |
Bartonella bacilliformis KC583 |
4684760
|
|
121602308
|
BARBAKC583_0326 |
CP000524 |
YP_988646 |
invasion protein B |
Virulence factor |
MUTATION: mutagenesis of ialB decreased bacterial association and invasion of human erythrocytes by 47 to 53% relative to controls [Ref7073:Coleman and Minnick, 2001].
|
11401976
|
|
|
trwD |
Bartonella birtlesii |
|
|
260446905
|
|
|
|
TrwD component of type IV secretion system |
Virulence factor |
MUTATION: trwD mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
trwE |
Bartonella birtlesii |
|
|
260446904
|
|
|
|
TrwE component of type IV secretion system |
Virulence factor |
MUTATION: trwE mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
trwF |
Bartonella birtlesii |
|
|
260446903
|
|
|
|
TrwF component of type IV secretion system |
Virulence factor |
MUTATION: trwF mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
trwJ2 |
Bartonella birtlesii |
|
|
260446899
|
|
|
|
TrwJ2 component of type IV secretion system |
Virulence factor |
MUTATION: trwJ2 mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
trwLA |
Bartonella birtlesii |
|
|
260446889
|
|
|
|
KTrwL1 component of type IV secretion system |
Virulence factor |
MUTATION: trwL1 mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
trwLB |
Bartonella birtlesii |
|
|
260446890
|
|
|
|
TrwL2 component of type IV secretion system |
Virulence factor |
MUTATION: trwL2 mutant is attenuated in adhesion and invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
ialB |
Bartonella birtlesii |
|
|
547729
|
|
|
|
Invasion protein B |
Virulence factor |
MUTATION: ialB mutant is attenuated in invasion of murine erythrocytes [Ref7074:Vayssier-Taussat et al., 2010].
|
20548954
|
|
|
badA |
Bartonella henselae str. Houston-1 |
|
119874507
|
119874508
|
|
|
ABM05732.1 |
adhesin A |
Virulence factor |
MUTATION: badA mutant have attenuated adherence to endothelial cells [Ref7075:Riess et al., 2004].
|
15534369
|
|
|
bepA |
Bartonella henselae |
|
|
56368455
|
|
|
|
BepA protein |
Virulence factor |
MUTATION: Using a bepA-G mutant, which does not display anti-apoptotic activity, restoring bepA expression led to the restoration of the anti-apoptotic phenotype in HUVECs [Ref7076:Schmid et al., 2006].
|
17121462
|
|
|
bepG |
Bartonella henselae |
|
|
56368462
|
|
|
|
BepG protein |
Virulence factor |
MUTATION: Expression of BepG in the Bep-deficient DeltabepA-G mutant restored invasome-mediated internalization in HUVECs [Ref7077:Rhomberg et al., 2009].
|
19302579
|
|
|
virB4 |
Bartonella henselae str. Houston-1 |
2865827
|
|
49476012
|
BH13280 |
U23447 |
YP_034053 |
virB4 protein |
Virulence factor |
MUTATION: virB4 mutant is attenuated in the capacity to grow in co-culture with, invade into, or survive within endothelial cells [Ref7078:Schmid et al., 2004].
|
15049812
|
|
|
virD4 |
Bartonella tribocorum CIP 105476 |
5829850
|
|
163868786
|
Btr_1701 |
AM260525 |
YP_001610010 |
conjugal transfer coupling protein TraG |
Virulence factor |
MUTATION: virD4 mutant is attenuated in rats [Ref7078:Schmid et al., 2004].
|
15049812
|
