Victors

trwF
Victor ID	4573
Gene Name	trwF
Sequence Strain (Species/Organism)	Bartonella birtlesii
NCBI Protein GI	260446903
Other Database IDs	CDD:187032 CDD:132874 InterPro: IPR010258 InterPro: IPR014148 UniProtKB/TrEMBL: D0AAZ6
Taxonomy ID	111504
Gene Strand (Orientation)	?
Protein Name	TrwF component of type IV secretion system
Protein Length	268
Protein Note	VirB9/CagX/TrbG, a component of the type IV secretion system; cl11423
Protein Sequence	>gi\|260446903\|emb\|CBG76057.1\| TrwF component of type IV secretion system [Bartonella birtlesii] MKKLTFLALLSSFSFLYTVPVQALKTPSNSQYDHRIRYVTYNVADVVQIETVLGVATHIILEEGERYITH AFGDSDAYAFAHKGRHIFIKPKAELANTNLIVVTDKRSYKFRLQFRNDRAGATYELAFHYPDTNTQKSEA NSQHLDIERGFHQGVKGYNLSYTMSGNQDIAPINAWDNGRITYFKFPANMDMPSIYLVDAEGNESLIPRT VIGSSNDIIAVHKVNPKWLIRLGKRALAVFNEAYDPNGVANTTGTVSSMVHRVNKGGK
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: trwF mutant is attenuated in adhesion and invasion of murine erythrocytes (Vayssier-Taussat et al., 2010).
References	*Vayssier-Taussat et al., 2010:* Vayssier-Taussat M, Le Rhun D, Deng HK, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis HJ, Mavris M, Arnaud L, Yang H, Wang J, Quebatte M, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS pathogens. 2010; 6(6); e1000946. [PubMed: 20548954].


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