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trwJ2

Victor ID 4574
Gene Name trwJ2
Sequence Strain (Species/Organism) Bartonella birtlesii
NCBI Protein GI 260446899
Other Database IDs CDD:164091
InterPro: IPR012991
UniProtKB/TrEMBL: D0AAZ2
Taxonomy ID 111504
Gene Strand (Orientation) ?
Protein Name TrwJ2 component of type IV secretion system
Protein Length 242
Protein Note Type IV secretion system proteins; cl06849
Protein Sequence
>gi|260446899|emb|CBG76053.1| TrwJ2 component of type IV secretion system [Bartonella birtlesii]
MKKLITIAVITVFSGVPSYGGEPPSYGPINVETKSAKMIDYEMHRGNLGYQIQSDSEIDLLKEQIISIEK
LRQSIMGSRTRSQVKKIDDGGLYFLNPQFIYDVTKQSDLGKKIPSIVRTIMSEENYLRTAPLSEARETID
ERSQYAAIISKAVSLHVFQEIENRFEQIADMLLTLDQMRDLKGLGEMKMRMKGLLAMIQNEATKLQMVIH
SHNIEKTLIHRLQRKRNVQILGSINRGMPTIR

Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trwJ2 mutant is attenuated in adhesion and invasion of murine erythrocytes (Vayssier-Taussat et al., 2010).
References
Vayssier-Taussat et al., 2010: Vayssier-Taussat M, Le Rhun D, Deng HK, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis HJ, Mavris M, Arnaud L, Yang H, Wang J, Quebatte M, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS pathogens. 2010; 6(6); e1000946. [PubMed: 20548954].