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trwE

Victor ID 4572
Gene Name trwE
Sequence Strain (Species/Organism) Bartonella birtlesii
NCBI Protein GI 260446904
Other Database IDs CDD:186623
InterPro: IPR005498
UniProtKB/TrEMBL: D0AAZ7
Taxonomy ID 111504
Gene Strand (Orientation) ?
Protein Name TrwE component of type IV secretion system
Protein Length 389
Protein Note Bacterial conjugation TrbI-like protein; cl04242
Protein Sequence 
>gi|260446904|emb|CBG76058.1| TrwE component of type IV secretion system [Bartonella birtlesii]
MFDNKKGDEINKNAERGYAEQKHIEGAYGSSELGLERRPIIPGARALLMVGLIVIIAVPIALTWKALKMR
NSIEVEEEKPQQTVQQIIPNYVPRVIEEPKVEEEEKKPEDSTQEIPATLAKLLQTTIPPHLIKDSEELAR
KRMLSSGLNSGGSSEGSTEPSKNNASNDDRNSGALFDHLQPVRLGHSQAVQLNNRDLLITQGTQIDCTLE
TKIITTQPGMTTCHLTRDVYSTSGRVVLLDRGSKVVGFYPSGIQQGQTRVFVQWSRIETPSGVIVNLDSP
GTGPLGEAGIGGWIDTHFWQRFGGAIMVSIIGDLGEWVKDKIWRKDRDNKENKERVQSQGVHNAESVVTD
VLQNSINITPTLYKNQGERVNIFVARDLDFSDVYSLVTR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trwE mutant is attenuated in adhesion and invasion of murine erythrocytes (Vayssier-Taussat et al., 2010).
References
Vayssier-Taussat et al., 2010: Vayssier-Taussat M, Le Rhun D, Deng HK, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis HJ, Mavris M, Arnaud L, Yang H, Wang J, Quebatte M, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS pathogens. 2010; 6(6); e1000946. [PubMed: 20548954].