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trwD

Victor ID 4571
Gene Name trwD
Sequence Strain (Species/Organism) Bartonella birtlesii
NCBI Protein GI 260446905
Other Database IDs CDD:163021
CDD:29996
GOA:D0AAZ8
InterPro: IPR001482
InterPro: IPR014155
UniProtKB/TrEMBL: D0AAZ8
Taxonomy ID 111504
Gene Strand (Orientation) ?
Protein Name TrwD component of type IV secretion system
Protein Length 354
Protein Note P-type DNA transfer ATPase VirB11; TIGR02788
Protein Sequence
>gi|260446905|emb|CBG76059.1| TrwD component of type IV secretion system [Bartonella birtlesii]
MMSTASLHVNGIQKDQAVAQLLQPLDHFLEDPKITELSINRPCEVWTKNFEGWHVHNVPELTAAFLQTLI
TAIIVYNGMAPRSINYVRLPGGQRGTIIQTPAVIDGTLSFVIRKHSLIVKTLEELNNEGVFDNFADVSFN
KPLEKEAENLLSKQDFTRLEPFEVQLLRLKRDKKILEFLEECVLHKRNIIIAGKTGSGKTTFARSLIEKV
PIEERMITIEDVHELFLPNHPNHVHMLYGNGAGRVPADECLDACLRQSPDRIFLAELRGNEAWEYLNSLN
TGHPGSITTTHANNALQTFERCATLIKRSEVGRQLDLEMIKVVLYTTVDVVLFFKDRKLSEIFYDPIFAK
SKIV

Molecule Role Virulence factor
Molecule Role Annotation MUTATION: trwD mutant is attenuated in adhesion and invasion of murine erythrocytes (Vayssier-Taussat et al., 2010).
References
Vayssier-Taussat et al., 2010: Vayssier-Taussat M, Le Rhun D, Deng HK, Biville F, Cescau S, Danchin A, Marignac G, Lenaour E, Boulouis HJ, Mavris M, Arnaud L, Yang H, Wang J, Quebatte M, Engel P, Saenz H, Dehio C. The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS pathogens. 2010; 6(6); e1000946. [PubMed: 20548954].