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bepA

Victor ID 4579
Gene Name bepA
Sequence Strain (Species/Organism) Bartonella henselae
NCBI Protein GI 56368455
Other Database IDs CDD:186284
GOA:Q6G2A9
InterPro: IPR003812
UniProtKB/TrEMBL: Q6G2A9
Taxonomy ID 38323
Gene Strand (Orientation) ?
Protein Name BepA protein
Protein Length 544
Protein Note Fic/DOC family; cl00960
Protein Sequence 
>gi|56368455|emb|CAD89506.1| BepA protein [Bartonella henselae]
MPKAKAKTKNTEIISPHHYVYPNTTTLKNKYGIKNLNAFLEKCSHDTAKAMINLREESLPEYFDTAYLCH
IHQQLFKNTFEWAGYLRHIPFTFADGTTAAMPEMKRTGWKNAFAIGDEIQEGLQRLDQTLAEKNNLQGLT
REEFNSEAIELFNSLNQLHPFREGNGRTQRLFFENLAKAAGHQLNFSLITKERMMVASVAVAENGDLEPM
QHLFEDISNPEKIRLLKEFMHTMKNTGRNVNDRPVMVAKEGETYTGTYRGAGLEGFALNVKGAYIIGNID
HLPPEQLKILKPGDKITFTAPKAEELKKTLIPKETLVPLTKLEIAEMVAEDAFVHTCRDQICSLSKIVYG
SQGVLNKNIIEIIKNPSKGQQLATQIERTPYSVHSLAGFDLICFKTGARVRAEKHVALLSCAVANFTHAV
KHARQEITKEHQAEQNRLRQEVPMPSQSLQDLLSLPKEFQQKALGVSPLLQKELTSLLQKVNSRLSSSEQ
RALRENNHETLAKNLGVSEQKAKEITKTVMKAREVQQKSQTRTVSHSKTLAMAS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Using a bepA-G mutant, which does not display anti-apoptotic activity, restoring bepA expression led to the restoration of the anti-apoptotic phenotype in HUVECs (Schmid et al., 2006).
References
Schmid et al., 2006: Schmid MC, Scheidegger F, Dehio M, Balmelle-Devaux N, Schulein R, Guye P, Chennakesava CS, Biedermann B, Dehio C. A translocated bacterial protein protects vascular endothelial cells from apoptosis. PLoS pathogens. 2006; 2(11); e115. [PubMed: 17121462].