| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
acuM |
Aspergillus fumigatus Af293 |
3513314
|
|
71001768
|
AFUA_2G12330 |
AAHF01000001 |
XP_755565 |
|
Virulence factor |
MUTATION: acuM mutant is attenuated in G. mellonella and murine models of invasive aspergillosis [Ref7042:Liu et al., 2010].
|
21062375
|
|
|
kre2 |
Aspergillus fumigatus Af293 |
3510739
|
|
70997663
|
AFUA_5G10760 |
AAHF01000003 |
XP_753570 |
|
Virulence factor |
MUTATION: kre2 (afmnt1) mutant is attenuated in mice [Ref7043:Wagener et al., 2008].
|
18708564
|
|
|
pig-a |
Aspergillus fumigatus YJ-407 |
|
45593795
|
45593796
|
|
|
AAS68360.1 |
phosphatidylinositol:UDP-GlcNAc transferase PIG-A |
Virulence factor |
MUTATION: afpig-a mutant is attenuated in immunosuppressed mice [Ref7044:Li et al., 2007].
|
17501924
|
|
|
alb1 |
Aspergillus fumigatus Af293 |
3513291
|
|
71002828
|
AFUA_2G17600 |
AAHF01000001 |
XP_756095 |
|
Virulence factor |
MUTATION: alb1 mutant is attenauted in mice [Ref7045:Tsai et al., 1998].
|
9620950
|
|
|
areA |
Aspergillus fumigatus Af293 |
3505289
|
|
70984747
|
AFUA_6G01970 |
AAHF01000012 |
XP_747880 |
|
Virulence factor |
MUTATION: areA mutant has delayed onset of pulmonary aspergillosis in mice compared to the wild type [Ref7046:Hensel et al., 1998].
|
9669338
|
|
|
cgrA |
Aspergillus fumigatus |
|
12000390
|
12000391
|
|
|
AAG28884.1 |
CGRA |
Virulence factor |
MUTATION: cgrA mutant is attenuated in immunosuppressed mice [Ref7047:Bhabhra et al., 2004].
|
15271935
|
|
|
chsC |
Aspergillus fumigatus H237 |
|
|
1523778
|
|
|
|
chitin synthase C |
Virulence factor |
MUTATION: a chsC/ChsG double mutant is attenuated in mice [Ref7048:Mellado et al., 1996].
|
8736545
|
|
|
chsG |
Aspergillus fumigatus H237 |
|
|
1197187
|
|
|
|
chitin synthase G |
Virulence factor |
MUTATION: a chsC/ChsG double mutant is attenuated in mice [Ref7048:Mellado et al., 1996].
|
8736545
|
|
|
cnaA |
Aspergillus fumigatus Af293 |
3511045
|
|
70997942
|
AFUA_5G09360 |
AAHF01000003 |
XP_753703 |
|
Virulence factor |
MUTATION: cnaA mutant is attenuated in mice [Ref7049:Steinbach et al., 2006].
|
16835453
|
|
|
cpcA |
Aspergillus fumigatus Af293 |
3509491
|
|
70993474
|
AFUA_4G12470 |
AAHF01000005 |
XP_751584 |
|
Virulence factor |
MUTATION: cpcA mutant is attenauted in mice [Ref7050:Krappmann et al., 2004].
|
15101984
|
|
|
crzA |
Aspergillus fumigatus Af293 |
3507698
|
|
70991180
|
AFUA_1G06900 |
AAHF01000007 |
XP_750439 |
|
Virulence factor |
MUTATION: crzA mutant is attenuated in mice [Ref7051:Soriani et al., 2008].
|
18298443
|
|
|
fos-1 |
Aspergillus fumigatus Af293 |
3508218
|
|
70992129
|
AFUA_6G10240 |
AAHF01000006 |
XP_750913 |
|
Virulence factor |
MUTATION: fos-1 is attenuated in mice [Ref7052:Clemons et al., 2002].
|
12146755
|
|
|
GEL2 |
Aspergillus fumigatus CBS 144.89 |
|
7208315
|
7208316
|
|
|
AAF40139.1 |
beta (1-3) glucanosyltransferase Gel2p |
Virulence factor |
MUTATION: gel2 mutant is attenuated in mice [Ref7053:Mouyna et al., 2005].
|
15916615
|
|
|
glfA |
Aspergillus fumigatus CBS 144-89 |
|
67008315
|
67008316
|
|
|
CAI38754.2 |
UDP-galactopyranose mutase |
Virulence factor |
MUTATION: glfA deletion mutant is attenuated in a low-dose mouse model of invasive aspergillosis [Ref7054:Schmalhorst et al., 2008].
|
18552284
|
|
|
gliP |
Aspergillus fumigatus Af293 |
3508160
|
|
70992013
|
AFUA_6G09660 |
AAHF01000006 |
XP_750855 |
|
Virulence factor |
MUTATION: gliP mutant is attenuated in mice immunosuppressed by hydrocortisone [Ref7055:Sugui et al., 2007].
|
17601876
|
|
|
gpaB |
Aspergillus fumigatus Af293 |
3510275
|
|
70995816
|
AFUA_1G12930 |
AAHF01000004 |
XP_752663 |
|
Virulence factor |
MUTATION: gpaB mutant is almost avirulent in a low-dose murine inhalation model [Ref7056:Liebmann et al., 2004].
|
15322014
|
|
|
laeA |
Aspergillus fumigatus Af293 |
3509858
|
|
70996160
|
AFUA_1G14660 |
AAHF01000004 |
XP_752835 |
|
Virulence factor |
MUTATION: laeA mutant is attenuated in mice [Ref7057:Bok et al., 2005].
|
16151250
|
|
|
lysF |
Aspergillus fumigatus Af293 |
3511364
|
|
70998032
|
AFUA_5G08890 |
AAHF01000003 |
XP_753748 |
|
Virulence factor |
MUTATION: lysF mutant is attenauted in mice [Ref7058:Liebmann et al., 2004b]
|
15052376
|
|
|
mcsA |
Aspergillus fumigatus ATCC 46645 |
|
63028050
|
63028051
|
|
|
CAI61947.1 |
methylcitrate synthase |
Virulence factor |
MUTATION: MSCA mutant is attenuated in Galleria mellonella [Ref7059:Maerker et al., 2005].
|
16008561
|
|
|
medA |
|
|
|
|
|
|
|
|
Virulence factor |
MUTATION: medA mutant is attenuated in Galleria mellonella and in a murine model of invasive aspergillosis [Ref7060:Gravelat et al., 2010].
|
19889083
|
|
|
pabaA |
Aspergillus fumigatus Af293 |
3505208
|
|
70984154
|
AFUA_6G04820 |
AAHF01000012 |
XP_747596 |
|
Virulence factor |
MUTATION: pabaA mutant is attenauted in mice [Ref7061:Brown et al., 2000].
|
10931287
|
|
|
pes1 |
Aspergillus fumigatus Af293 |
3510659
|
|
70995289
|
AFUA_1G10380 |
AAHF01000004 |
XP_752404 |
intestinal alkaline phosphatase VII |
Virulence factor |
MUTATION: pes1 mutant is attenuated in Galleria mellonella model system [Ref7062:Reeves et al., 2006].
|
16759234
|
|
|
pkaC1 |
Aspergillus fumigatus Af293 |
3513486
|
|
71001742
|
AFUA_2G12200 |
AAHF01000001 |
XP_755552 |
|
Virulence factor |
MUTATION: pkaC1 mutant is almost avirulent in a low-dose murine inhalation model [Ref7056:Liebmann et al., 2004]. |
15322014
|
|
|
pkaR |
Aspergillus fumigatus |
|
15825179
|
15825180
|
|
|
AAL09588.1 |
cAMP-dependent protein kinase regulatory subunit PKAR |
Virulence factor |
MUTATION: pkaR mutant is attenuated in an immunosuppressed mouse model [Ref7063:Zhao et al., 2006].
|
16861675
|
|
|
pksP |
Aspergillus fumigatus ATCC46645 |
|
|
3163925
|
|
|
|
polyketide synthase |
Virulence factor |
MUTATION: pksP mutant is attenuated in mice [Ref7064:Langfelder et al., 1998].
|
9832321
|
|
|
pyrG |
Aspergillus fumigatus Af293 |
3513211
|
|
71000978
|
AFUA_2G08360 |
AAHF01000001 |
XP_755170 |
|
Virulence factor |
MUTATION: pyrG mutant is avirulent in mice [Ref7065:D'Enfert et al., 1996].
|
8926121
|
|
|
rasB |
Aspergillus fumigatus Af293 |
3513137
|
|
71000862
|
AFUA_2G07770 |
AAHF01000001 |
XP_755112 |
|
Virulence factor |
MUTATION: rasB mutant is attenuated in mice [Ref7066:Fortwendel et al., 2005]. |
16339716
|
|
|
rhbA |
Aspergillus fumigatus Af293 |
3511630
|
|
70998720
|
AFUA_5G05480 |
AAHF01000003 |
XP_754082 |
|
Virulence factor |
MUTATION: rhbA mutant is attenuated in mice [Ref7067:Panepinto et al., 2003].
|
12704156
|
|
|
sidA |
Aspergillus fumigatus Af293 |
3513640
|
|
71000844
|
AFUA_2G07680 |
AAHF01000001 |
XP_755103 |
|
Virulence factor |
MUTATION: sidA mutant is attenuated in D. melanogaster [Ref7068:Chamilos et al., 2010].
|
20370364
|
|
|
sidD |
Aspergillus fumigatus Af293 |
3506154
|
|
70986336
|
AFUA_3G03420 |
AAHF01000010 |
XP_748662 |
|
Virulence factor |
MUTATION: sidD mutant is attenuated in D. melanogaster [Ref7068:Chamilos et al., 2010].
|
20370364
|
|
|
zafA |
Aspergillus fumigatus Af293 |
3510549
|
|
70995221
|
AFUA_1G10080 |
AAHF01000004 |
XP_752374 |
|
Virulence factor |
MUTATION: zafA mutant is attenuated in a murine model of invasive aspergillosis [Ref7069:Moreno et al., 2007].
|
17542914
|
|
|
pacC |
Aspergillus nidulans FGSC A4 |
2873843
|
|
67524795
|
AN2855.2 |
BN001306 |
XP_660459 |
|
Virulence factor |
MUTATION: pacC mutant is attenuated in mice [Ref7070:Bignell et al., 2005].
|
15686555
|
|
|
palB |
|
|
|
68052402
|
|
|
|
Calpain-like protease palB |
Virulence factor |
MUTATION: palB mutant is attenuated in porcine corneal invasion [Ref7071:Hua et al., 2010].
|
19850840
|
