Victors

areA
Victor ID	4539
Gene Name	areA
Sequence Strain (Species/Organism)	Aspergillus fumigatus Af293
NCBI Gene ID	3505289
NCBI Protein GI	70984747
Locus Tag	AFUA_6G01970
Genbank Accession	AAHF01000012
Protein Accession	XP_747880
Taxonomy ID	330879
Chromosome No	6
Gene Starting Position	302647
Gene Ending Position	305375
Gene Strand (Orientation)	+
Protein pI	8.8
Protein Weight	91142.63
Protein Length	881
DNA Sequence	>gi\|71025133:302647-305375 Aspergillus fumigatus Af293 chromosome 6, whole genome shotgun sequence AATGTCGGGGATGAGCCATGGAGGAGCGCCTAAAGCAGCGCGACCGACTCCAACCGCTGTCTCTGCCTCC TCTGGTTACGACATCGCCGATGCTGACCGATCATCCTCTTCTCATTTCCACCACACCTCCCAATTGTCCG ACGATTTCTCCCTTGGTTCTCCCCTCAGTCCACCTGACTCCGCTCATGTCCAGGACGGTTTGCTCCAGGA CTCTCTTTTTCCCGAGTGGAGGAACGCCGCTCCCCGAGACGGGGTAGAAAGTCCAGATGAGATGCAACGG AAAGATCCACTGGCTACTCAAATATGGAAGCTCTATTCTAGAACAAAAGCTCAGTTACCCAATCAGGAGC GCATGGAAAATCTCACGTGGCGCATGATGGCTATGAGCTTGAAACGCAAGGAACGGGAAAGGCTTCAGCA GAATAATCGGTATGTCTATGATAATTCAGGTGCTTGGACAATCGCTTTTTTTGAAGTCAGGTTGGACTCA TCTTCCCTCGTTTACAATATAGTCCTTCGACGAAGAACAGTGGCAGCTCGGAGCCGAGCGGTATTGCCCA ACTCCGTCAGACCGACCGCCCTTCCTTTGCACGGCCATCAACATCCACCGATCTTGCCTCCGACCCCATG AACATCGACGACTTCATAGTTCCTATCGAGTCGCCCGCCGATCGCCCTCGGTCACCGCCAACAGATAAAG CGGCGACCTCATCCGTGGCGATCCCCATCAAGTCTCGCAAGGACCAATCGGCCGATGCCACTCCTGTGCC AGCCTCCTTTCCTCATCCACCTCAGGACCAGCGCAGAAACAACGAGTTTGGCTATGTACCCCGTCGCGTG CGCAAGACAAGCATCGATGAGCGCCAATTCTTCAATCTCCAGATTCCCACTCGCAAGCGGCCAGCCGAGT CCTCTCCCCAGGTGCCGCCCGTGTCGAACGCCATGCTGGCTCAGGATCCCAATTTCTCGGCCGGTGTTCC TGATTACACCCTCGACAATGCGTCGTCTGGGTTTGCTCTCCACTCTAATACTCAAAACCACCACAACAAC AATAACCTTACGTCCCCCGGCGTCCCCTTTGGATTGGACACTTTCAGCTTGGGCGAAGATCCGATTCTAT CGTCGGCCGGTCCTTACCAGGCGCACTTTACTTTCTCTCCCAGCGACTCTCCCATGACGTCGGCCAACCC GTTTGCGAATGTATATGCGCAGACCCCGATTGCCTCGTCGCTTAATTCGACAGAGTTCTTTTCTCCTCCT CCGTCGGGGTACCAGTCCTCCGTATCAACACCTCAGCCCACATACGATGGGGATCACTCGATGTATTTTG ATATGCCTTCGATTGATGCTCGGACTCAACGGCGTATCCCCAACTACATTACCCACCGTTCGAACTTGTC TGCTTCGCTGCAACCGCGATTCATGTTTAACAACAATACCGGTAGTGAGCAGCAGCACGGGATGACCCAC GGCAGCAACTCGTCATCTGCTGTTCATTCTCCGAACTATACTATGAGTCAGTCGCAGCATGTCGATCCGA CACAGGTGTTAAACCCAAGCGATTTCCCTACATCGAACACTCATGCCGGCATATTCTCATTCGGTGCGGA TTCTGACAACGAAGATGATGATGCCAACAACTACACCGAGCGGGCTGGCCTGGCTATGCCCGCCGACTTT GGTGATGACAACGCCGGCGACATGAACGGCTTGAACTGGGACGGTCAGTTCCCTGGATCTTTCCACTCCC TGTCTGGATTCAGCGTGCAGCACCGGAAACATGTCACGATCGGCTCGGCAGACATGATGGACACTCCCAG TGAGTGGAACCAAGGCGGCAGTCTTGGCCGCACGCACGGATCCGCAGCCTCGGTCAGTGAAGTGCGCAAC CGCGAGCAGGACCCTCGTCGTCAGAAGATTGCTCGTACCACGTCGACGCCTAACACCAACCAGCTGCTGC GCCAAAGCATGAACAATACTTCCCACACATCGCCAAACACCCCTCCAGAGTCGGGACTCAGCAGTGCTGT TCCGTCCAGACCGGCGAGCCCTGGTGGCTCCAAGAACGGTGATCAGAACAATGGGCCAACCACCTGTACC AACTGCTTCACTCAGACCACACCACTGTGGCGCCGTAATCCCGAGGGTCAACCCCTCTGTAACGCCTGCG GTCTGTTCCTCAAACTGCATGGAGTGGTTCGTCCGTTGTCGTTGAAGACAGACGTCATCAAGAAGCGAAA CCGCAGTAGCGCCAACAGTCTTGCTGTGGGCGCGTCTCGTTCGTCGAAGAAGTCCTCTCGCAAAAACTCC GTAGCCCAGATTTCCATGACGACACCTACATCGAGCCGCGCACAGAGTAACACTACATCCGAGTCCCCGC CGGCCATTCCTGGAGGCGCGGCCTCAGCCGCTGGCAGGACCGCAGGTGCGACGGGCAAATCCGGTGTGGT CCCCATCGCGGCAGCACCGCCAAAGGCTACTCCTACGAGCGCTGGACAAAGCCGCAGCACTGTTCAGGTA GCCCCCAAGCGCCAACGGCGCCTGGAGAAAGCCAGTGAGACGGATGCAGCCGACGACAGCAATAAACCCA GCACTTCGTCTGGGGGCCGGTCGAAGGTGGTTCCATTAGCACCTGCCATGCCTCCGGCGGCGGTGAACCC GGCCAATCATAGCATTGCTGGGGGTCAGGGTGCAAGCCAGGAATGGGAGTGGTTGACCATGAGTTTGTG
Protein Sequence	>gi\|70984747\|ref\|XP_747880.1\| GATA transcriptional activator AreA [Aspergillus fumigatus Af293] MSGMSHGGAPKAARPTPTAVSASSGYDIADADRSSSSHFHHTSQLSDDFSLGSPLSPPDSAHVQDGLLQD SLFPEWRNAAPRDGVESPDEMQRKDPLATQIWKLYSRTKAQLPNQERMENLTWRMMAMSLKRKERERLQQ NNRPSTKNSGSSEPSGIAQLRQTDRPSFARPSTSTDLASDPMNIDDFIVPIESPADRPRSPPTDKAATSS VAIPIKSRKDQSADATPVPASFPHPPQDQRRNNEFGYVPRRVRKTSIDERQFFNLQIPTRKRPAESSPQV PPVSNAMLAQDPNFSAGVPDYTLDNASSGFALHSNTQNHHNNNNLTSPGVPFGLDTFSLGEDPILSSAGP YQAHFTFSPSDSPMTSANPFANVYAQTPIASSLNSTEFFSPPPSGYQSSVSTPQPTYDGDHSMYFDMPSI DARTQRRIPNYITHRSNLSASLQPRFMFNNNTGSEQQHGMTHGSNSSSAVHSPNYTMSQSQHVDPTQVLN PSDFPTSNTHAGIFSFGADSDNEDDDANNYTERAGLAMPADFGDDNAGDMNGLNWDGQFPGSFHSLSGFS VQHRKHVTIGSADMMDTPSEWNQGGSLGRTHGSAASVSEVRNREQDPRRQKIARTTSTPNTNQLLRQSMN NTSHTSPNTPPESGLSSAVPSRPASPGGSKNGDQNNGPTTCTNCFTQTTPLWRRNPEGQPLCNACGLFLK LHGVVRPLSLKTDVIKKRNRSSANSLAVGASRSSKKSSRKNSVAQISMTTPTSSRAQSNTTSESPPAIPG GAASAAGRTAGATGKSGVVPIAAAPPKATPTSAGQSRSTVQVAPKRQRRLEKASETDAADDSNKPSTSSG GRSKVVPLAPAMPPAAVNPANHSIAGGQGASQEWEWLTMSL
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: areA mutant has delayed onset of pulmonary aspergillosis in mice compared to the wild type (Hensel et al., 1998).
References	*Hensel et al., 1998:* Hensel M, Arst HN Jr, Aufauvre-Brown A, Holden DW. The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis. Molecular & general genetics : MGG. 1998; 258(5); 553-557. [PubMed: 9669338].


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