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chsC

Victor ID 4541
Gene Name chsC
Sequence Strain (Species/Organism) Aspergillus fumigatus H237
NCBI Protein GI 1523778
Other Database IDs CDD:149461
CDD:187019
CDD:132997
CDD:133033
GOA:Q92197
UniProtKB/UniProt: Q92197
Taxonomy ID 5085
Gene Strand (Orientation) ?
Protein Name chitin synthase C
Protein Length 889
Protein Note Chitin synthase N-terminal; pfam08407
Protein Sequence 
>gi|1523778|emb|CAA63929.1| chitin synthase C [Aspergillus fumigatus]
MGTPRPYSAHSPQESRSSFYSQPSQSPTQPTYGRDDAEDQQQSLLRRSLASPNGWSYDDPNVSTDSLRRY
TLHDPGITAFAPPYPESEAADVRSARMSGYSGIEMDAWQRRQGVKPSALRRYGTRKINLVQGSVLSVDYP
VPSAIQNAIQAEYRDAEEAFHEEFTHMRYTAATCDPDEFTLRNGYNLRPAMYNRHTERLIAITYYNEDKV
LTARTLHGVMQNVRDIVNLKKSEFWNKGGPAWQKIVVCLVFDGIEPCDKNTLDVLATIGVYQDGVMKKDV
DGRETVAHIFEYTTQLSVTPTQQLVRPQPNDPSNLPPVQMLFCLKQKNSKKINSHRWLFNAFSRILNPEI
CILLDAGTKPGSKSLLALWEAFYNDKTLGGACGEIHAMLGRGWRNVLNPLVAAQNFEYKISNILDKPLES
AFGYVSVLPGAFSAYRYRAIMGRPLEQYFHGDHTLSKRLGKKGIEGMNIFKKNMFLAEDRILCFELVAKA
GYKWHLTYVKASKGETDVPEAAPEYISQRRRWLNGSFAASLYSIMHFGRIYKSGHSFVRMFFLHIQMIYN
CCQLIMTWFSLASYWLTSSVIMDLVGTPSSHNKYKAWPFGNDASPIVNFFVKYGYLLVLMLQFVLALGNR
PKAYTMSFLWFSLVQFYVLILSFYLVANAFMGGMIDFDFDQGVGNFLSSFFSSTGGGIVLIALVSTYGIY
IVASILYMDPWHILTSSWAYFLGMTTSINILMVYAFCNWHDVSWGTKGSDKADALPSAQTKKADASKSNF
IEEIDKPQADIDSQFEATVKRRLAPYQEPKEDSTISLDDSYRNFRTSLVLLWILSNLLVSLLITSDGIRK
MCLTNTSTTRTQYYFQVILWATAGLSIFRFIGSIYFLGKSGILCCVTRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a chsC/ChsG double mutant is attenuated in mice (Mellado et al., 1996).
References
Mellado et al., 1996: Mellado E, Aufauvre-Brown A, Gow NA, Holden DW. The Aspergillus fumigatus chsC and chsG genes encode class III chitin synthases with different functions. Molecular microbiology. 1996; 20(3); 667-679. [PubMed: 8736545].