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cgrA

Victor ID 4540
Gene Name cgrA
Sequence Strain (Species/Organism) Aspergillus fumigatus
NCBI Nucleotide GI 12000390
NCBI Protein GI 12000391
Protein Accession AAG28884.1
Taxonomy ID 5085
Gene Strand (Orientation) ?
Protein Name CGRA
Protein Note similar to the essential nucleolar protein CGR1 of Saccharomyces cerevisiae
DNA Sequence 
>gi|12000390|gb|AY008837.1| Aspergillus fumigatus CGRA (cgrA) mRNA, complete cds
CTTGCAGATCAGGGCCATCTCATCTCATCTTCTACAAACCCGTCCTTACATAGTTTCTTTCATGATTCTG
CTGGCAATGTCGTCGGCAATCCCAACCTCATCTGTCAACCCCGTCAAGGGTATGAGAAAGAATGGCAAAA
ACTGGCACGATTCCAAGAAACCATTTCGTCCCACCTCAGGCCTGACAAGCTATGAGAAAAGGTTGGAAGC
ACGCAAGCGGCAGGAGGCAGTTAAGGAACACGAACGTGAGCTGAGGGAAGAAAAAGAGGCAGAACGGAAG
GCTCAAATACAAAAGATCAAGGATCGGAGAGCTGCCAAGGAAGAAAAGGAACGCTACGAGAAAATGGCAG
AGAAAATGCATCGCAAACGTGTTGAGCGGCTAAAGCGAAGGGAGAAGCGTAATAAGTTACTTCACTCGTG
ACAGCAGAAGAATCTCTCTCCGCTGTTGCTTCAGTGTCTGCCATGCATTAACTTCATCCTACTGTCCTAC
CCGCAGTACCCATTCACATTTGCGGCAGATACCAGGTTGTTTTCTATTCCCTCGGTTCTTCAGTTCTTCA
GATATTACATTACTCGAGAAATTGGCGGCGATGCAGGAGTTTGGTTGGTTTTAATTGTTTCAGTCTCCTT
GACCTGATTTGTATGACATGCAATGTTTCGACGGAAGACTATCTCGGTGAATATACGTCATGAATCATCT
TGACTTCTTATAATCCACATTTCCTTTTTC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cgrA mutant is attenuated in immunosuppressed mice (Bhabhra et al., 2004).
References
Bhabhra et al., 2004: Bhabhra R, Miley MD, Mylonakis E, Boettner D, Fortwendel J, Panepinto JC, Postow M, Rhodes JC, Askew DS. Disruption of the Aspergillus fumigatus gene encoding nucleolar protein CgrA impairs thermotolerant growth and reduces virulence. Infection and immunity. 2004; 72(8); 4731-4740. [PubMed: 15271935].