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cnaA

Victor ID 4543
Gene Name cnaA
Sequence Strain (Species/Organism) Aspergillus fumigatus Af293
NCBI Gene ID 3511045
NCBI Protein GI 70997942
Locus Tag AFUA_5G09360
Genbank Accession AAHF01000003
Protein Accession XP_753703
Taxonomy ID 330879
Chromosome No 5
Gene Starting Position 2408569
Gene Ending Position 2410481
Gene Strand (Orientation) -
Protein pI 5.67
Protein Weight 61160.83
Protein Length 558
DNA Sequence 
>gi|71025132:2408569-2410481 Aspergillus fumigatus Af293 chromosome 5, whole genome shotgun sequence
TTTAGGCTTCCCTAGTCTCCCGGGCGGCATCTCTTTGCCGACGAGACCTGCCAGAGCCGGCGGACCTGTG
CTTTATTAGGCGATGAGACTTCTTGCCAGGAGAAGGGTTGACTTACATGCTAATTCTCCGGGCGACGGTA
GCCAAGCCGGTATCATTGTCTGCCTCCTGTTGCGCACGCTCGAGGGCAGCCCGTCTTTCCTCTTCGCTTC
TCTTGATGACCTCCTCGTGAGACGGTGGAAGACGCTCGTTCTGCAAGTCAACCTTGCGAGCGTCCTCAAA
GTTGGTAATAGCCTGTTTGATTCCTTCGGCGCCAAGCATCAGGGTACCAGCTGGGAGACGGCCACCAGCA
GCTGTCTTGAGTTCCGTAACTCTCTCAGACTCCTCCCGCAACACCTGGAAGACACGCGAGAGACGTCCGA
TGGCAAGAATCTTGTTCTTGATCGCCCGTCTTTTGAATTCGCTGCTCTCCACGTCCATTGGGAGCGGAGG
AGACGGAGCAGAAGGTGACACGGAGGTAGGAGTCTCGTCTTCGAGCTCCTCCTTGGAGCAGGTATTGAGA
ATGGCGATGAGCATATCGGTGATCTTCTCACCGACGAAAGGAAGCGACCACGTAAACACGTCCATGAAGT
TTGGCAACCAGTACGGGTGAGGCGTGCAGTTGAACTGTCGGATATTCATGACGTTGTTCTCGTACTTCAG
CACGGCAGCCTTGTTGTTGTAGACATCCAAGTAGTTGGGAGCACTGAAGATAGTCATCACACTTGGAAAT
CCGGTCGTGCGAGTTTTTCGGTACATGCGATATCCAGCGTCCTGCGCCTCGTGTGCTCGAATGATCGACA
ATAGGTTGTTCTTTTCAAGGAAAGCGCAAGCCGCGGGGTACGAGAAGAAGTAAGAACAGCCTCGAACACT
GTTGTGAACAAAGTAATCTCCCGTTTTTTCTTGTCCGAACTCTTCAAGCGGATCAGCCCACAGGATGTCG
CACATCAAACCGTGAGTCGGGGGCTCTCTGAAACGATCAATCTGTAGACTCACATGAGTGAAGGAACTAA
AAGGAACATTCAAGCAGCTTTGAACGTACCGATTTGATATCTTCGAGAGTGTGAAGTTCAGGACTTAGGC
CACCATGTATACACAGGAATTGCTTGTTCATGACCGCCGCCAGCGGCAACGCGCAGAATGATTCAATGCA
GGCCTCATAGATACGCTCGCTGTATTTATGCTTGCACTCCAGCTTGAAGGTGAAGTAATCCGTGAGATGC
CTGCATTCGTGGTTGCCTCGGAGCAGCCAAAGGCTGTTCGGGTACCAGATCTTCAGGGCCCAGAGATATA
AAACGCACTAGCCGATATCAGCTTCCCCGATCATCAAGCGTCCCAGGAAGTCATCTCTCACCTCAATGCT
GAAATAACCTCTGTCGACATAATCACCCAGGAAAAGATACCTCGTCTCGGACGGATCGCCACCGACTTCG
AAGAGTTTCATCAAGTCATAGTATTGACCGTGAACGTCGCCACAGACGGTGATCGGCGCATCCATCTCTA
GCAGATTAGGTTCAGATCTCAGAATCTGAGTTCCGGCATGTATAATCCATAGCGCCTGCTCCTCTGTAAG
ACGACCTTCCCGATAGAAATGCTGTTTCAGGAACTGGAGGTTGGGCTTCGAGGGGTCTTCAGGAGACCAG
AACATTTCATCCGTGGGAGTACTTAAAGCCGGCGCTTGCACCTCTGGATTCGCAAATTGTTAGAGACGGC
GAATGTTCAAATCGAGACTCAGCAGAGTCTCAATCCTAGGCCATACCTTTGATCACTCGTTCCAGCGTGG
AGACTTGAGTGCCATCCTCCATGGTGTGTAGGGTGAAGTCGATCTCCGGGACGGGCTTCTTGTCCCTCAC
CGCGCGCGCCAGTGCTTGATCCA
Protein Sequence 
>gi|70997942|ref|XP_753703.1| calcineurin catalytic subunit CnaA [Aspergillus fumigatus Af293]
MDQALARAVRDKKPVPEIDFTLHTMEDGTQVSTLERVIKEVQAPALSTPTDEMFWSPEDPSKPNLQFLKQ
HFYREGRLTEEQALWIIHAGTQILRSEPNLLEMDAPITVCGDVHGQYYDLMKLFEVGGDPSETRYLFLGD
YVDRGYFSIECVLYLWALKIWYPNSLWLLRGNHECRHLTDYFTFKLECKHKYSERIYEACIESFCALPLA
AVMNKQFLCIHGGLSPELHTLEDIKSIDRFREPPTHGLMCDILWADPLEEFGQEKTGDYFVHNSVRGCSY
FFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYRKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNV
MNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILNTCSKEELEDETPTSVSPSAPSPPLPMDV
ESSEFKRRAIKNKILAIGRLSRVFQVLREESERVTELKTAAGGRLPAGTLMLGAEGIKQAITNFEDARKV
DLQNERLPPSHEEVIKRSEEERRAALERAQQEADNDTGLATVARRISMSAGSGRSRRQRDAARETREA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cnaA mutant is attenuated in mice (Steinbach et al., 2006).
References
Steinbach et al., 2006: Steinbach WJ, Cramer RA Jr, Perfect BZ, Asfaw YG, Sauer TC, Najvar LK, Kirkpatrick WR, Patterson TF, Benjamin DK Jr, Heitman J, Perfect JR. Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus. Eukaryotic cell. 2006; 5(7); 1091-1103. [PubMed: 16835453].