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pyrG

Victor ID 4560
Gene Name pyrG
Sequence Strain (Species/Organism) Aspergillus fumigatus Af293
NCBI Gene ID 3513211
NCBI Protein GI 71000978
Locus Tag AFUA_2G08360
Genbank Accession AAHF01000001
Protein Accession XP_755170
Taxonomy ID 330879
Chromosome No 2
Gene Starting Position 2153117
Gene Ending Position 2154021
Gene Strand (Orientation) -
Protein pI 6.68
Protein Weight 28282.7
Protein Length 278
DNA Sequence 
>gi|71025129:2153117-2154021 Aspergillus fumigatus Af293 chromosome 2, whole genome shotgun sequence
ATCATGACTTGCCGCATACTCTGGCCATATAAGCTTCCCAGCCTTCTTTCTGGTACCGCTGTGCAGCTTC
AACCGGGTCGGGAGCAGCGTAGATGCCTCGACCGGCGATGATAAAGTCGGCACCGCGTCCAATAGCCGAT
GCAGGAGTCTGGTATTGCTGTCCAAGCTTATCTCCTTTGGAAGAGAGGTTCACACCCGTCGTGAAGACCA
CGAAATCTTCATCCTCCGAGGCTGAAGACACATCCGACTGCACTTCCGTCAGGGCCCGCGTCGACACGAA
ACCCATAACGAAGTTCTTGTATTTGCGAGCGTAGTCAACCGATGCCTTGGTATACTCGCCCGTAGCCAGC
GATCCTTTGGAGGTCATCTCTGCCAGGACCAACAGTCCTCTCTCAGGACCATAGGGGAAGTCTTGCGCAG
ATGCGGTCTGGGCCAGAGCCTCGACGATGCCCTCGCCAGGGAGAACGCTGCAGTTGATAATGTGGGCCCA
TTCGGAGATCCTCAGAGCACCGCCGTGGTATTGCTTCTGGACGGTATTGCCGATGTCGATGAATTTGCGG
TCCTCGAAGATCAAAAAGTTGTGCTTTTGAGCCAGCACATTCAGGCCATTGATAGTGTCGACGCTGAAAT
CGGTGAGGATGTCGATGTGTGTCTTGATGACGGCGATGTAGGGACCGAGACCTGTATCATCAAAAGTTGA
TTAGTCCATTGCTAGACGGCATATGTATTGGATCCAACAGCTTCCGTACGGTCAGCGAGGTCCAGGAGTT
CTCGGGTTGTCGTCACATCAGCAGAGACGGTAACGTTTGTCTTCTTTGCTTCGGCAATCTCAAAAAGTCT
CTTTGCCAGAGGATTGGGGTGCTTGCTGGCTCGAGCACCGTAAGTCAATTGCGACTTGGACGACA
Protein Sequence 
>gi|71000978|ref|XP_755170.1| orotidine 5'-phosphate decarboxylase PyrG [Aspergillus fumigatus Af293]
MSSKSQLTYGARASKHPNPLAKRLFEIAEAKKTNVTVSADVTTTRELLDLADRLGPYIAVIKTHIDILTD
FSVDTINGLNVLAQKHNFLIFEDRKFIDIGNTVQKQYHGGALRISEWAHIINCSVLPGEGIVEALAQTAS
AQDFPYGPERGLLVLAEMTSKGSLATGEYTKASVDYARKYKNFVMGFVSTRALTEVQSDVSSASEDEDFV
VFTTGVNLSSKGDKLGQQYQTPASAIGRGADFIIAGRGIYAAPDPVEAAQRYQKEGWEAYMARVCGKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pyrG mutant is avirulent in mice (D'Enfert et al., 1996).
References
D'Enfert et al., 1996: D'Enfert C, Diaquin M, Delit A, Wuscher N, Debeaupuis JP, Huerre M, Latge JP. Attenuated virulence of uridine-uracil auxotrophs of Aspergillus fumigatus. Infection and immunity. 1996; 64(10); 4401-4405. [PubMed: 8926121].