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crzA

Victor ID 4545
Gene Name crzA
Sequence Strain (Species/Organism) Aspergillus fumigatus Af293
NCBI Gene ID 3507698
NCBI Protein GI 70991180
Locus Tag AFUA_1G06900
Genbank Accession AAHF01000007
Protein Accession XP_750439
Taxonomy ID 330879
Chromosome No 1
Gene Starting Position 1962165
Gene Ending Position 1964486
Gene Strand (Orientation) -
Protein pI 6.53
Protein Weight 79619.85
Protein Length 754
DNA Sequence 
>gi|71025128:1962165-1964486 Aspergillus fumigatus Af293 chromosome 1, whole genome shotgun sequence
ATCAATAGAAGTTACCGGCAGCAGAATACCCAGCATTAATACCAGATACGCTACTGAGCCCCGAGTCGTC
ATCCTCGAAGCCAAATTCATTGCCGGAGCTGGCGTCGAAGCTGCTACGGCCCCCTATGTCGCTGGGATCA
TCCGCCGATGCAGCAATCTGGTCCCACTGCAAGGTCTGGAGAGCGGGATATTGAGCCAGAAGCGCGGCAG
GCAGCACAAAATTACCAGCATGTGGGTTGTCCACAGGTACCATCACTTGTTGTGGAAGTGGTTGCAAATG
ATGTTGCTGCTGGTCCATGAGCGAACGCTCCCTTTCTTGCGACTCCTCATCTAGCAGCGGCTTGATACAG
ATCCGCCCCGCCTCTGAACGGAAATGACGCCCCAGAGCGTCCGCCCGGGCAAATCGGCGACCGCAGCCCC
ATTGTCCGCCGCGGGAGAGTTCTCCCTGACAAACGAACTTCTTCTCGCCCGAGTGTAGCCCTTCGTGTCG
TTTGCGATCATGCTGTCGAGCGAAGGCTTTGCCACATACAGTGCAGACAAATGGCCGCTCGTCCGTGTGG
GTTCGGAGATGTGACCGCAAATTGTAAGCCCGAGTGAAGCGCTTCGGACACAAGTTGCACTGAAACGTTG
CGGGATGTTTCTGGACACGCTTCGAGTCGTTGGGGCTAGCCCCTGGTCGCTGGGGATCGGCAAGGCCCAG
GATGTAATTGCGGCTATCGATCGACGAGGTCGACAGACGTCGGTTGGATCTGGACGGAGACGGATCGCGT
GAGCTTGGATTGCTCTGCTGCTGACGTCCAAAAGAGTCGAACGGAGAAAGTGAGCGAGGAGTAGTAGGCG
CAAGGGGGTCCAGGCTGCTCGAAGTCGACGAGGAGCGCAGCCGACTGGTGCTGGGATGGGCATATGGATC
AGACTTGCTACGCCCGCGGGAGCCTGCATTCTTGATTAGTTCCTTGATGACAGACGAAAATCGAATGCAG
GGCTACTTACGTGTGGACGAAGGTGGAGGACTCAAGGAGTCGAGGTTGCTGGCCGGTTTTGAAGGTCCAA
AACTGGGGATCCGCGACGGGGGTGCAAATTCCACGTTGATGGACGGCGGAGCCATCTGAGAGGCTTGGCC
GATGTCCACAGACGGATGAGTCCCCTGCGACATATTCATCATGCCCTCCGCTCCATTGCCATACATATCA
TTTGGAGGGGTCGGATACTGCGTGTTCGGAGCGGGGCCAGAGAGATAAGGCACATTGGGCATCATTTCCT
GTCCCTGTTGGGGCATCAGCCGCGGAGAGATGTACGGACTGTGCGCCGGGCTAAACCCTTGATGCTGCTG
GTGCTGCTCGGACAAGGTGAAGTTCTCGATCCCAAGAGCACTATCGTATAAACTGGGATCGTTTTGGGGT
GCCAGAAGCGGAGAGGGATTGTTGTCTACACCATCAAAAGACTCATGTTGTGAGAGGTACGGAGAAGGAG
CAGCGGACGAGATTTCGGAAACCTCGGATGGAGCTCGTCGATGGCCCTGGAAAGCAGCACTATTGCCCAT
GACGGCCTGCCAGTCAGGATGTGTGTTACTGGTGAGAAAGGCGGCCGTGGCGGGGTCCAAGGATGCATGA
CGGGAATGCTGAGGGGTATAGTAAGCCACGGTTGTCGAACCTTGGGTTGACATTGGACCCGGTGAGGAGT
GCTGCTGTTGCTCGAGAGGGGAGATCTGCGGAGAAGTCGAGGAATGGGAGGAGGGTATCTGGGTCGGATG
CGACTGCTGGTGGACCTGAGGGTCAAGCAGAAGGGAGGAGTCGTACTCAGGAGCAGTATTACTACTGGGA
CTGTGAGTCTGGTAGACGGTGTTGAAGTCGTACTCGGTGGCATTGGAGTTCAAAAGATCGGAGAAGTTAT
CATCGAGGGAGGGCTGCTGGTGGTGCTGTTGTTGCGACTGCTGCTGTATTGGCAAGCCGCGAGACTCATT
GAACTGAGGAACCAGACCGGTGCCGTACGATTGCGGAATCTGAAGACTATTTGCGTAGTTCTGGTCGGTC
TGCGATGCAGGAGTGCCTGAGAGATAGCCAGCGGCAGTATAACCATACGATTCGGCGGAAGGGCTAACGT
TGTTGCTATTGGGATCGAAGGACGAATTGGCAAATGAACTAGCTGTAGCGATCGAAGAATCGAGATCTAA
GCCAGTGACTGTTCCTGTAAATTGTCCTTGATGTTGTTGATGCTGTTGCTGTTGCTGCTGCTGATGAGGA
TGGGGAGAGCGGCTGACGCCGCGGCTTTTAACGCCGGGTGCAGGAGACTGCCCCAACTCAGGGAACATCT
CCTGTGAAGCCA
Protein Sequence 
>gi|70991180|ref|XP_750439.1| C2H2 transcription factor Crz1 [Aspergillus fumigatus Af293]
MASQEMFPELGQSPAPGVKSRGVSRSPHPHQQQQQQQHQQHQGQFTGTVTGLDLDSSIATASSFANSSFD
PNSNNVSPSAESYGYTAAGYLSGTPASQTDQNYANSLQIPQSYGTGLVPQFNESRGLPIQQQSQQQHHQQ
PSLDDNFSDLLNSNATEYDFNTVYQTHSPSSNTAPEYDSSLLLDPQVHQQSHPTQIPSSHSSTSPQISPL
EQQQHSSPGPMSTQGSTTVAYYTPQHSRHASLDPATAAFLTSNTHPDWQAVMGNSAAFQGHRRAPSEVSE
ISSAAPSPYLSQHESFDGVDNNPSPLLAPQNDPSLYDSALGIENFTLSEQHQQHQGFSPAHSPYISPRLM
PQQGQEMMPNVPYLSGPAPNTQYPTPPNDMYGNGAEGMMNMSQGTHPSVDIGQASQMAPPSINVEFAPPS
RIPSFGPSKPASNLDSLSPPPSSTRSRGRSKSDPYAHPSTSRLRSSSTSSSLDPLAPTTPRSLSPFDSFG
RQQQSNPSSRDPSPSRSNRRLSTSSIDSRNYILGLADPQRPGASPNDSKRVQKHPATFQCNLCPKRFTRA
YNLRSHLRTHTDERPFVCTVCGKAFARQHDRKRHEGLHSGEKKFVCQGELSRGGQWGCGRRFARADALGR
HFRSEAGRICIKPLLDEESQERERSLMDQQQHHLQPLPQQVMVPVDNPHAGNFVLPAALLAQYPALQTLQ
WDQIAASADDPSDIGGRSSFDASSGNEFGFEDDDSGLSSVSGINAGYSAAGNFY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: crzA mutant is attenuated in mice (Soriani et al., 2008).
References
Soriani et al., 2008: Soriani FM, Malavazi I, da Silva Ferreira ME, Savoldi M, Von Zeska Kress MR, de Souza Goldman MH, Loss O, Bignell E, Goldman GH. Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA. Molecular microbiology. 2008; 67(6); 1274-1291. [PubMed: 18298443].