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laeA

Victor ID 4551
Gene Name laeA
Sequence Strain (Species/Organism) Aspergillus fumigatus Af293
NCBI Gene ID 3509858
NCBI Protein GI 70996160
Locus Tag AFUA_1G14660
Genbank Accession AAHF01000004
Protein Accession XP_752835
Taxonomy ID 330879
Chromosome No 1
Gene Starting Position 3918020
Gene Ending Position 3919286
Gene Strand (Orientation) +
Protein pI 6.32
Protein Weight 41090.95
Protein Length 373
DNA Sequence 
>gi|71025128:3918020-3919286 Aspergillus fumigatus Af293 chromosome 1, whole genome shotgun sequence
GATGTTTCTCAACGGGCAGGGCGGACAGCGACCTCCGATGGTGGCCTTCCCGCCACTTAACGTTCGCGGA
TCTATTTCGTCAGGTTTCAATGCCCTAGGCCGCTCAAGAAACAACTCCGATGCTATGGACATCTATACAA
TCACAGACAGGGGTCCCGCTGCAGAGAGAGACCCGGCCGCTGGTCGTTGGCACGCCAATGGTTCCCCAAG
TATTAATTCTACCAGTAGCAAGTATATCTCTCTTTCCCTCCTCCCTTCTATTTTCATATTCTTGCTCTCC
CTTCTTTCGAGCTGCCGTCAAAGCGGTTAATATTGCAACTTTGTTACCATTGGGTGACTAATATACAATC
TTCCTTTTCCTCTCTTCTCCCTTTAGGAATCCTGACAGATACCCTTGCTATCAGGAGAACGGACGAACAT
ACCATGGATACCGCAAAGGAATCTACATGTTGCCGTGCGACGAGCAGGAGCAGGATCGTCTAGATATATT
CCACAAGCTTTTCACTGTGGCGAGAGTCTCGGACGGACTGATCTATGCTCCACATCCCACCAACGGCCGG
TTTCTCGATTTGGGATGTGGGACAGGGATTTGGGCGATCGATGTGGCCAACAAGTATCCAGAAGCCTTCG
TCGTTGGGGTTGATTTGGCCCCCATACAACCTCCAAATCACCCGAGAAATTGCGACTTTTATGCGCCATT
CGACTTTGAAAGCCTTTGGGCTCTTGGGGAGGATTCGTGGGATCTGATTCACATGCAGATGGGCTCCGGC
AGCGTTGCAAGTTGGCCCAACCTCTATCGGAGGATTTATTCCCATCTCCGTCCCGGTGCCTGGTTTGAGC
AGGTCGAAATCGATTTCGAACCCCGTTGCGATGATCGCTCTTTGGAAGGCTTGGCTATTCGACAATGGTA
CCAGTTATTGAAACAAGCCACAGAGGAAACCATGCGGCCGGTTGCTCACAATTCACGTGAAACGATTCGA
AATCTGCAGGAGGCCGGATTTACTGAGATCGACCATCAAATGGTTGGACTCCCTCTCAACCCGTGGCATG
AGGACGAGCATGAGAGAAGAGTGGCTCGTTGGTATAACCTAGCCATCTCGGAGAGTATTGAGACGATGAG
CCTTGCCCCTTTCAGCCGTGTGTTCGGTTGGCCGATCGAACGAATCAAGCAAATAGCAGCCGATGTTAAA
TCGGAGGCTTTCAATAAAGAGATCCATACTTACAACATACTGCATATATACCAGGCTCGAAAACCTCTCG
CCAATTG
Protein Sequence 
>gi|70996160|ref|XP_752835.1| regulator of secondary metabolism LaeA [Aspergillus fumigatus Af293]
MFLNGQGGQRPPMVAFPPLNVRGSISSGFNALGRSRNNSDAMDIYTITDRGPAAERDPAAGRWHANGSPS
INSTSSKNPDRYPCYQENGRTYHGYRKGIYMLPCDEQEQDRLDIFHKLFTVARVSDGLIYAPHPTNGRFL
DLGCGTGIWAIDVANKYPEAFVVGVDLAPIQPPNHPRNCDFYAPFDFESLWALGEDSWDLIHMQMGSGSV
ASWPNLYRRIYSHLRPGAWFEQVEIDFEPRCDDRSLEGLAIRQWYQLLKQATEETMRPVAHNSRETIRNL
QEAGFTEIDHQMVGLPLNPWHEDEHERRVARWYNLAISESIETMSLAPFSRVFGWPIERIKQIAADVKSE
AFNKEIHTYNILHIYQARKPLAN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: laeA mutant is attenuated in mice (Bok et al., 2005).
References
Bok et al., 2005: Bok JW, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Keller NP. LaeA, a regulator of morphogenetic fungal virulence factors. Eukaryotic cell. 2005; 4(9); 1574-1582. [PubMed: 16151250].