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kre2

Victor ID 4536
Gene Name kre2
Sequence Strain (Species/Organism) Aspergillus fumigatus Af293
NCBI Gene ID 3510739
NCBI Protein GI 70997663
Locus Tag AFUA_5G10760
Genbank Accession AAHF01000003
Protein Accession XP_753570
Taxonomy ID 330879
Chromosome No 5
Gene Starting Position 2749464
Gene Ending Position 2750836
Gene Strand (Orientation) -
Protein pI 6.28
Protein Weight 45225.56
Protein Length 400
DNA Sequence 
>gi|71025132:2749464-2750836 Aspergillus fumigatus Af293 chromosome 5, whole genome shotgun sequence
GTCAACTCTGTTCTTCAGCCCCCTCTGGCTTCTCCATATCATTGATCTGGAACCACCGGGATGTGCCTGA
ACATATTGAGATTAATGCAAGTCTCAAGAAGGCGGTAAGTGAACTTACAGGAATATCCCTTCCAATCGAA
ATTCTCACTAGGATTACAGTGGCATTTCAGGTCCAGCCTCATCTGCTCACTGGTCGGGCAATGTGTGAAT
GGAATGTGGTAGTAAGCAATCTCGTTGAAAAAATGAATCTCTTCCTTCTTGAGCATGATGCCGGCCGCAA
TGGAATGAACTGGGGCGTCTCCCCATCGCTCATAGAAGAAGCCGCCGTCGTGGTCAAGAGCATCGAAATA
GTCAAGATACTGCTTCGATCTCAACCACTCTAAGCTTCCAATCTCAAAGTTGGACCACTGGGTAAGATGA
TCAGTCAGCAGCAGCAGCCGGACTTCTAATGAGGGAAACTCACAAAGTGACATTTGTTGTATGTCTTTCC
TCCATCATCACTCAAGAAACCCATCGCATTTCCTTCTGCAATATGCTCTGGGTGATTGCCCATGAACTTC
TTGACGCTATCCCATAGACTGGGGATGGTGTCGTAATATTCATACAAACTAAGGACGAAACTGTACTTCT
TGTTCTGTTCCTTCATAAGCTTGAATGGGTCGAAGCTGATGTCGCAATAAAGCTCAATGCTGGGTTCCAC
GCGCCAGTAGTACTCGTAGTTCAGCATCAGTGGATGGCGGAAGAAGAAACCGGACTCGTAGCGGCACATG
TGGCGGTAGCTCTCGGAGTCACCATAGATGATCTTCTTCTGTCCCATTTCCTCTCGGACTTTCTTGGCTT
TTTCTTGATCAATCCAATCGGGGTACGACCAGTGTTCCTTTGGAATTTCACCATAGAATGTTTTTCCAGA
CACCAGGGATGTGGTGACCTTCTTAAAAGTGTCGTCAAATGGCTTGTCGTTGAGAAAGACCCAATCATAA
TGGTAATTACGGTTGAAGCGATCCTCGACCTGCCGGATCGATTTCGCAATATCCCAGACATCGGAATTGC
GAGCCAGCGTGACGAATGTCGCATTCACTCGGCCAACTGGCGCAGTATTCGCGCTTCCCGGTGTCTCCTT
CACCGGCGGTTTTGGTGGCGCGTCATTGTGCGCTTTATCAGATTGTGAGATGGTATCTTTGTAATTCGCG
GGACTCAACTTCGATCCGATATTTTCGGGGATGGGAATCGAACTGCGAGAGATTAAGAAAAATACTGCCA
ACCCCTGATACTGGGTCAGTGGCACTGGGAGAGGGCACAGGGGGGAAAATTCCAAGGACGACGAACCACC
GCAGCAAAGAGCAAGTAGCGCATATATTTCGGTCCCGAAGACA
Protein Sequence 
>gi|70997663|ref|XP_753570.1| alpha-1,2-mannosyltransferase (Kre2) [Aspergillus fumigatus Af293]
MSSGPKYMRYLLFAAVGLAVFFLISRSSIPIPENIGSKLSPANYKDTISQSDKAHNDAPPKPPVKETPGS
ANTAPVGRVNATFVTLARNSDVWDIAKSIRQVEDRFNRNYHYDWVFLNDKPFDDTFKKVTTSLVSGKTFY
GEIPKEHWSYPDWIDQEKAKKVREEMGQKKIIYGDSESYRHMCRYESGFFFRHPLMLNYEYYWRVEPSIE
LYCDISFDPFKLMKEQNKKYSFVLSLYEYYDTIPSLWDSVKKFMGNHPEHIAEGNAMGFLSDDGGKTYNK
CHFWSNFEIGSLEWLRSKQYLDYFDALDHDGGFFYERWGDAPVHSIAAGIMLKKEEIHFFNEIAYYHIPF
THCPTSEQMRLDLKCHCNPSENFDWKGYSCTSRWFQINDMEKPEGAEEQS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: kre2 (afmnt1) mutant is attenuated in mice (Wagener et al., 2008).
References
Wagener et al., 2008: Wagener J, Echtenacher B, Rohde M, Kotz A, Krappmann S, Heesemann J, Ebel F. The putative alpha-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen Aspergillus fumigatus is required for cell wall stability and full virulence. Eukaryotic cell. 2008; 7(10); 1661-1673. [PubMed: 18708564].