| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
aroC from Burkholderia pseudomallei 1106a |
Burkholderia pseudomallei 1106a |
4899749
|
|
126453136
|
BURPS1106A_1713 |
|
YP_001065984.1 |
chorismate synthase |
Virulence factor |
MUTATION: aroC mutant is highly attenuated in mice [Ref6612:Srilunchang et al., 2009]. |
19323044
|
|
|
pabB from Burkholderia pseudomallei 1106a |
Burkholderia pseudomallei 1106a |
4900497
|
|
126452015
|
BURPS1106A_3583 |
|
YP_001067814.1 |
para-aminobenzoate synthase, component I |
Virulence factor |
MUTATION: pabB mutant is attenuated in mice [Ref6613:Breitbach et al., 2008]. |
19121696
|
|
|
pabB from Burkholderia pseudomallei 1106a |
Burkholderia pseudomallei 1106a |
4902449
|
|
126454445
|
BURPS1106A_3308 |
|
YP_001067545.1 |
para-aminobenzoate synthase, component I |
Virulence factor |
MUTATION: pabB mutant is attenuated in mice [Ref6613:Breitbach et al., 2008]. |
19121696
|
|
|
BURPS668_A2153 |
Burkholderia pseudomallei 668 |
4887799
|
|
126445249
|
BURPS668_A2153 |
CP000571 |
YP_001063147 |
BopA protein |
Virulence factor |
MUTATION: BopA mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
pabB from Burkholderia pseudomallei 668 |
Burkholderia pseudomallei 668 |
4882076
|
|
126438699
|
BURPS668_3556 |
|
YP_001060561.1 |
para-aminobenzoate synthase, component I |
Virulence factor |
MUTATION: pabB mutant is attenuated in mice [Ref6613:Breitbach et al., 2008]. |
19121696
|
|
|
pabB from Burkholderia pseudomallei 668 |
Burkholderia pseudomallei 668 |
4882105
|
|
126440966
|
BURPS668_3275 |
|
YP_001060286.1 |
para-aminobenzoate synthase, component I |
Virulence factor |
MUTATION: pabB mutant is avirulent in mice [Ref6613:Breitbach et al., 2008]. |
19121696
|
|
|
purM from Burkholderia pseudomallei 668 |
Burkholderia pseudomallei 668 |
4883825
|
|
126442046
|
BURPS668_3267 |
|
YP_001060278.1 |
phosphoribosylaminoimidazole synthetase |
Virulence factor |
MUTATION: purM mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
aroC from Burkholderia pseudomallei 668 |
Burkholderia pseudomallei 668 |
4884302
|
|
126441149
|
BURPS668_1689 |
|
YP_001058730.1 |
chorismate synthase |
Virulence factor |
MUTATION: aroC mutant is highly attenuated in mice [Ref6612:Srilunchang et al., 2009]. |
19323044
|
|
|
sctU from Burkholderia pseudomallei 1710b |
Burkholderia pseudomallei 1710b |
3693839
|
|
76819009
|
BURPS1710b_A0427 |
|
YP_335586.1 |
type III secretion system protein |
Virulence factor |
MUTATION: sctU mutant is attenuated in mice [Ref6616:Warawa and Woods, 2005]. |
15621426
|
|
|
bopA |
Burkholderia pseudomallei 1710b |
3694081
|
|
76817646
|
BURPS1710b_A0562 |
CP000125 |
YP_335721 |
BopA protein |
Virulence factor |
MUTATION: BopA mutant was attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
sctU from Burkholderia pseudomallei 1710b |
Burkholderia pseudomallei 1710b |
3694226
|
|
76819722
|
BURPS1710b_A0680 |
|
YP_335839.1 |
type III secretion system protein |
Virulence factor |
MUTATION: sctU mutant is attenuated in mice [Ref6616:Warawa and Woods, 2005]. |
15621426
|
|
|
aroC from Burkholderia pseudomallei 1710b |
Burkholderia pseudomallei 1710b |
3690536
|
|
76809035
|
BURPS1710b_1867 |
|
YP_333268.1 |
chorismate synthase |
Virulence factor |
MUTATION: aroC mutant is attenuated in mice [Ref6612:Srilunchang et al., 2009]. |
19323044
|
|
|
pabB from Burkholderia pseudomallei 1710b |
Burkholderia pseudomallei 1710b |
3690587
|
|
76809867
|
BURPS1710b_3318 |
|
YP_334690.1 |
chorismate binding enzyme |
Virulence factor |
MUTATION: pabB mutant is attenuated in mice [Ref6613:Breitbach et al., 2008]. |
19121696
|
|
|
leuB |
Burkholderia pseudomallei K96243 |
3094947
|
|
53722725
|
BPSS1705 |
BX571966 |
YP_111710 |
3-isopropylmalate dehydrogenase |
Virulence factor |
MUTATION: leuB mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSS1509 |
Burkholderia pseudomallei K96243 |
3095047
|
|
53722531
|
BPSS1509 |
BX571966 |
YP_111516 |
hypothetical protein |
Virulence factor |
MUTATION: BPSS1509 mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
sctU from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3095565
|
|
53722427
|
BPSS1400 |
|
YP_111412.1 |
type III secretion system protein |
Virulence factor |
MUTATION: sctU mutant is attenuated in hamsters [Ref6616:Warawa and Woods, 2005]. |
15621426
|
|
|
BPSS2074 |
Burkholderia pseudomallei K96243 |
3095712
|
|
53723092
|
BPSS2074 |
BX571966 |
YP_112077 |
senescence marker protein-30 (SMP-30) family protein |
Virulence factor |
MUTATION: BPSS2074 (lpfA) mutant is attenuated in hamsters [Ref6621:Boddey et al., 2007]. |
16987331
|
|
|
bipD |
Burkholderia pseudomallei K96243 |
3096115
|
|
53722550
|
BPSS1529 |
BX571966 |
YP_111535 |
membrane antigen |
Virulence factor |
MUTATION: bipD mutant was attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
BPSS1539 |
Burkholderia pseudomallei K96243 |
3096285
|
|
53722560
|
BPSS1539 |
BX571966 |
YP_111545 |
hypothetical protein |
Virulence factor |
MUTATION: BPSS1539 mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
bopE |
Burkholderia pseudomallei K96243 |
3096393
|
|
53722546
|
BPSS1525 |
BX571966 |
YP_111531 |
G-nucleotide exchange factor |
Virulence factor |
MUTATION: bopE mutant is attenuated in mice [Ref6622:Stevens et al., 2004]. |
15289563
|
|
|
bsaZ |
Burkholderia pseudomallei K96243 |
3096627
|
|
53722555
|
BPSS1534 |
BX571966 |
YP_111540 |
surface presentation of antigens protein SpaS |
Virulence factor |
MUTATION: bsaZ mutant is attenuated in mouse macrophages [Ref6623:Stevens et al., 2002]. |
12410823
|
|
|
BPSS0067 |
Burkholderia pseudomallei K96243 |
3096819
|
|
53721107
|
BPSS0067 |
BX571966 |
YP_110092 |
phospholipase C precursor |
Virulence factor |
MUTATION: BPSS0067 mutant is attenuated in mice [Ref6624:Tuanyok et al., 2006]. |
16988221
|
|
|
BPSS2053 |
Burkholderia pseudomallei K96243 |
3096991
|
|
53723070
|
BPSS2053 |
BX571966 |
YP_112055 |
cell surface protein |
Virulence factor |
MUTATION: BPSS2053 mutant had reduced microbial adherence to human epithelial cells [Ref6625:Sim et al., 2008]. |
18927621
|
|
|
pmlI |
Burkholderia pseudomallei K96243 |
3097087
|
|
53721909
|
BPSS0885 |
BX571966 |
YP_110894 |
N-acylhomoserine lactone synthase |
Virulence factor |
MUTATION: pmll mutant is attenuated in mice [Ref6626:Valade et al., 2004]. |
15060030
|
|
|
BPSL1039 |
Burkholderia pseudomallei K96243 |
3091509
|
|
53718680
|
BPSL1039 |
BX571965 |
YP_107666 |
putative ABC transporter membrane protein |
Virulence factor |
MUTATION: BPSL1039 mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL1263 |
Burkholderia mallei |
3091526
|
|
53718898
|
BPSL1263 |
|
YP_107884.1 |
hypothetical protein |
Virulence factor |
MUTATION: BPSL1263 (cdpA) mutant has a 3-fold reduction in invasion of human lung epithelial cells and a 6-fold reduction in cytotoxicity on human macrophage cells [Ref6627:Lee et al., 2010]. |
20194589
|
|
|
lipB from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3091586
|
|
53718053
|
BPSL0413 |
|
YP_107039.1 |
lipoyltransferase |
Virulence factor |
MUTATION: lipB mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
hisF from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3091767
|
|
53720740
|
BPSL3133 |
|
YP_109726.1 |
imidazole glycerol phosphate synthase subunit HisF |
Virulence factor |
MUTATION: hisF mutant is attenuated in mice and has intracellular growth defects [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
wcbN |
Burkholderia pseudomallei K96243 |
3091825
|
|
53720402
|
BPSL2793 |
BX571965 |
YP_109388 |
putative D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase |
Virulence factor |
MUTATION: wcbN mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL2825 |
Burkholderia pseudomallei K96243 |
3091847
|
|
53720434
|
BPSL2825 |
BX571965 |
YP_109420 |
hypothetical protein |
Virulence factor |
MUTATION: BPSL2825 mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
BPSL0634 |
Burkholderia pseudomallei K96243 |
3092290
|
|
53718277
|
BPSL0634 |
BX571965 |
YP_107263 |
putative oxidoreductase |
Virulence factor |
MUTATION: BPSL0634 mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL1528 |
Burkholderia mallei |
3092312
|
|
53719162
|
BPSL1528 |
|
YP_108148.1 |
hypothetical protein |
Virulence factor |
MUTATION: Inactivation of gene BPSL1528 leads to impaired actin tail formation, reduced intracellular survival, and high-grade attenuation of virulence in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
aroB |
Burkholderia pseudomallei K96243 |
3092462
|
|
53720775
|
BPSL3168 |
BX571965 |
YP_109761 |
3-dehydroquinate synthase |
Virulence factor |
MUTATION: aroB mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
trpG |
Burkholderia pseudomallei K96243 |
3092485
|
|
53720660
|
BPSL3051 |
BX571965 |
YP_109646 |
anthranilate synthase component II |
Virulence factor |
MUTATION: trpG mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
purM from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3092877
|
|
53720427
|
BPSL2818 |
|
YP_109413.1 |
phosphoribosylaminoimidazole synthetase |
Virulence factor |
MUTATION: purM mutant is avirulent in mice [Ref6628:Propst et al., 2010]. |
20404077
|
|
|
purN from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3092878
|
|
53718549
|
BPSL0908 |
|
YP_107535.1 |
phosphoribosylglycinamide formyltransferase |
Virulence factor |
MUTATION: purN mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
wcbB |
Burkholderia pseudomallei K96243 |
3093047
|
|
53720417
|
BPSL2808 |
BX571965 |
YP_109403 |
putative capsular polysaccharide glycosyltransferase biosynthesis protein |
Virulence factor |
MUTATION: wcbB mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
wcbC |
Burkholderia pseudomallei K96243 |
3093048
|
|
53720416
|
BPSL2807 |
BX571965 |
YP_109402 |
putative capsular polysaccharide biosynthesis/export protein |
Virulence factor |
MUTATION: wcbC mutation is attenuated in mice [Ref6629:Reckseidler et al., 2001]. |
11119486
|
|
|
nth from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3093395
|
|
53718738
|
BPSL1103 |
|
YP_107724.1 |
endonuclease III |
Virulence factor |
MUTATION: nth mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL0872 |
Burkholderia pseudomallei K96243 |
3093782
|
|
53718511
|
BPSL0872 |
BX571965 |
YP_107497 |
MviN-like protein |
Virulence factor |
MUTATION: BPSLO872 (mviN) mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells [Ref6630:Ling et al., 2006]. |
17110975
|
|
|
BPSL0395 |
Burkholderia pseudomallei K96243 |
3093846
|
|
53718035
|
BPSL0395 |
BX571965 |
YP_107021 |
putative cytidylyltransferase |
Virulence factor |
MUTATION: BPSL0395 mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
wzm |
Burkholderia pseudomallei K96243 |
3093941
|
|
53720414
|
BPSL2805 |
BX571965 |
YP_109400 |
putative capsular polysaccharide export ABC transporter transmembrane protein |
Virulence factor |
MUTATION: wzm mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
ilvI |
Burkholderia pseudomallei K96243 |
3093947
|
|
53718832
|
BPSL1196 |
HB949671 |
YP_107818 |
acetolactate synthase 3 catalytic subunit |
Virulence factor |
MUTATION: ilvI mutant is attenuated in mice [Ref6631:Atkins et al., 2002]. |
12183585
|
|
|
fliC |
Burkholderia pseudomallei K96243 |
3094015
|
|
53720929
|
BPSL3319 |
BX571965 |
YP_109915 |
flagellin |
Virulence factor |
MUTATION: fliC mutant is attenuated in mice [Ref6632:Chua et al., 2003]. |
12654773
|
|
|
wcbD |
Burkholderia pseudomallei K96243 |
3094162
|
|
53720415
|
BPSL2806 |
BX571965 |
YP_109401 |
putative capsule polysaccharide export ABC transporter transmembrane protein |
Virulence factor |
MUTATION: wcbD mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL3147 |
Burkholderia pseudomallei K96243 |
3094200
|
|
53720754
|
BPSL3147 |
BX571965 |
YP_109740 |
putative lipoprotein |
Virulence factor |
MUTATION: BPSL3147 mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
serC from Burkholderia pseudomallei K96243 |
Burkholderia pseudomallei K96243 |
3094241
|
|
53720129
|
BPSL2519 |
|
YP_109115.1 |
phosphoserine aminotransferase |
Virulence factor |
MUTATION: serC mutant is attenuated in mice [Ref6633:Rodrigues et al., 2006]. |
16997946
|
|
|
recA |
Burkholderia pseudomallei K96243 |
3094325
|
|
53718415
|
BPSL0776 |
BX571965 |
YP_107401 |
recombinase A |
Virulence factor |
MUTATION: recA mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
BPSL1876 |
Burkholderia pseudomallei K96243 |
3094734
|
|
53719489
|
BPSL1876 |
BX571965 |
YP_108475 |
putative phospholipase |
Virulence factor |
MUTATION: BPSL1876 mutant is attenuated in mice [Ref6624:Tuanyok et al., 2006]. |
16988221
|
|
|
BPSL1705 |
Burkholderia pseudomallei K96243 |
3094881
|
|
53719320
|
BPSL1705 |
BX571965 |
YP_108306 |
hypothetical protein |
Virulence factor |
MUTATION: boaB (BPSL1705) mutant has reduced attachment to respiratory cells, and a boaA boaB double mutant was attenuated in murine macrophages [Ref6634:Balder et al., 2010]. |
20920184
|
|
|
GBP346_A0742 |
Burkholderia pseudomallei MSHR346 |
7887507
|
|
237811015
|
GBP346_A0742 |
CP001408 |
YP_002895466 |
putative type IV pilin protein PilA |
Virulence factor |
MUTATION: pilA mutant is attenuated in mice [Ref6833:Essex-Lopresti et al., 2005]. |
15664977
|
|
|
mviN |
Burkholderia pseudomallei MSHR346 |
7888150
|
|
237811120
|
GBP346_A0847 |
CP001408 |
YP_002895571 |
integral membrane protein MviN |
Virulence factor |
MUTATION: mviN mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells [Ref6630:Ling et al., 2006]. |
17110975
|
|
|
purM from Burkholderia pseudomallei MSHR346 |
Burkholderia pseudomallei MSHR346 |
7888461
|
|
237813669
|
GBP346_A3446 |
|
YP_002898120.1 |
phosphoribosylformylglycinamidine cyclo-ligase |
Virulence factor |
MUTATION: purM mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
nth from Burkholderia pseudomallei MSHR346 |
Burkholderia pseudomallei MSHR346 |
7889124
|
|
237811473
|
GBP346_A1203 |
|
YP_002895924.1 |
endonuclease III |
Virulence factor |
MUTATION: nth mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
ppsA |
Burkholderia pseudomallei MSHR346 |
7889272
|
|
237812786
|
GBP346_A2540 |
CP001408 |
YP_002897237 |
phosphoenolpyruvate synthase |
Virulence factor |
MUTATION: ppsA mutant is attenuated in mice [Ref6620:Cuccui et al., 2007]. |
17189432
|
|
|
hisF from Burkholderia pseudomallei MSHR346 |
Burkholderia pseudomallei MSHR346 |
7889294
|
|
237814060
|
GBP346_A3845 |
|
YP_002898511.1 |
imidazoleglycerol phosphate synthase, cyclase subunit |
Virulence factor |
MUTATION: hisF mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
purN from B urkholderia pseudomallei MSHR346 |
B urkholderia pseudomallei MSHR346 |
7889759
|
|
237811171
|
GBP346_A0898 |
|
YP_002895622.1 |
phosphoribosylglycinamide formyltransferase |
Virulence factor |
MUTATION: purN mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
rpoE |
Burkholderia pseudomallei MSHR346 |
7889774
|
|
237813202
|
GBP346_A2967 |
CP001408 |
YP_002897653 |
RNA polymerase sigma factor RpoE |
Virulence factor |
MUTATION: rpoE mutant is attenuated in mice [Ref6834:Thongboonkerd et al., 2007]. |
17346071
|
|
|
lipB from Burkholderia pseudomallei MSHR346 |
Burkholderia pseudomallei MSHR346 |
7890481
|
|
237810647
|
GBP346_A0371 |
|
YP_002895098.1 |
lipoyl(octanoyl) transferase |
Virulence factor |
MUTATION: lipB mutant is attenuated in mice [Ref6615:Pilatz et al., 2006]. |
16714590
|
|
|
serC from Burkholderia pseudomallei MSHR346 |
Burkholderia pseudomallei MSHR346 |
7890564
|
|
237813299
|
GBP346_A3066 |
|
YP_002897750.1 |
phosphoserine transaminase |
Virulence factor |
MUTATION: serC mutant is attenuated in mice [Ref6633:Rodrigues et al., 2006]. |
16997946
|
|
|
capsular polysaccharide |
Burkholderia pseudomallei |
|
|
|
|
|
|
|
Virulence factor |
MUTATION: a capsule mutant of B. pseudomallei was attenuated in an acute respiratory murine model [Ref7308:Warawa et al., 2009]. |
19752033
|
