Victors

mviN
Victor ID	3667
Gene Name	mviN
Sequence Strain (Species/Organism)	Burkholderia pseudomallei MSHR346
NCBI Gene ID	7888150
NCBI Protein GI	237811120
Locus Tag	GBP346_A0847
Genbank Accession	CP001408
Protein Accession	YP_002895571
Other Database IDs	UniProtKB-ID: C4KRQ5_BURPS UniRef100: UniRef100_C4KRQ5 UniRef90: UniRef90_Q3JVB5 UniRef50: UniRef50_Q3JVB5 UniParc: UPI0001A487A0 EMBL: CP001408 EMBL-CDS: ACQ95619.1 RefSeq_NT: NC_012695.1 ProtClustDB: CLSK930442
Taxonomy ID	536230
Chromosome No	I
Gene Starting Position	806948
Gene Ending Position	808726
Gene Strand (Orientation)	+
Protein Name	integral membrane protein MviN
Protein pI	11.28
Protein Weight	58553.71
Protein Length	592
Protein Note	identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695
DNA Sequence	>gi\|237810278:806948-808726 Burkholderia pseudomallei MSHR346 chromosome I, complete genome AATGCGCATGACAGGCTCAGAAACCGGCAATTATAACAACAAAATCAAGCGAGTGGCAAGCGGAAGCCGC ATCGGCCGAATGCCGGCGCCGGCGCTGGCGCGCGGGCCGGCGGGCTCGCGGCAGCGGCTGGTGAGCGGAG CGCCCCGAGCCGGTGCGCCGATGCCGGTGCGCGCCTTTTGCTCGAACGTATCGGTCGCCGCCGCCCGAGG TCCGTATAATAAGCGCCCCATGAATCTATTCCGAGCCCTGCTGACGGTCAGCGGCTTCACGCTGCTGTCG CGCGTGACCGGACTGGCCCGTGAGACGCTGATCGCCCGCGCGTTCGGCGCCAGTCAATTCACCGACGCGT TCTACGTCGCATTCCGTATTCCGAACCTGCTGCGCCGGCTGTCCGCCGAAGGCGCGTTTTCGCAGGCGTT CGTGCCGATTCTCGCCGAGTTCAAGAATCAAAAAGGGCACGATGCGACGAAGGCGCTGGTCGACGCGATG TCGACCGTGCTCGCGTGGGCGCTCGCGCTCCTGTCGCTCGCGGGGATCGCCGGCGCGTCGTGGGTGGTGT TCGCGGTCGCGTCGGGGCTGCGCACGGACGGCCAGGCGTTCCCGCTCGCCGTCGCGATGACGCGGATCAT GTTCCCGTACATCGTGTTCATTTCGCTCACCACGCTCGCGTCGGGCGTGCTCAACACGTACAAGCGTTTC TCGCTGCCGGCGTTCGCGCCCGTGCTGCTGAACGTCGCGTTCATCGTCGCGGCGGTGTTCGTCGCGCCGC ACCTGAAGGTGCCCGTCTATGCGCTCGCATGGGCGGTGATCGCGGGTGGCGCGCTGCAGTTCGCGGTGCA GTTGCCGGGGCTGAAGAAGATCGACATGATGCCCGCGATCGGCGTGAATCCGCTGCGCGCGCTCGCGCAC CCGGGCGTGAAGCGTGTGCTGGCGAAGATGGTGCCCGCGACGTTCGCGGTGTCGGTCGCGCAACTGTCGC TCATCATCAATACGAACATCGCGTCGCGGCTCGGGCAGGGCGCCGTGTCGTGGATCAATTACGCGGACCG GCTGATGGAGTTTCCGACCGCGCTCCTCGGCGTCGCGCTCGGCACGATCCTGCTGCCGAGCCTGTCGAAG GCGCACGTCGACGCCGATTCGACCGAGTATTCGGCGCTCCTCGACTGGGGCCTGCGGGTCACGTTCCTGC TCGCGGCGCCGAGCGCGCTCGCGCTGTTCTTCTTCGCCGAGCCGCTCACGGCGACGCTGTTCAATTACGG CAAATTCGACGCGCACACGGTCACGATGGTCGCGCGCGCGCTCGCGACGTACGGGATCGGCCTCGTCGGC ATCATCCTCATCAAGATCCTCGCACCCGGCTTCTATGCGAAGCAGGACATCAAGACGCCCGTGAAGATCG CGATCGGCGTGCTCGTCGTCACGCAGTTGTCGAACTACGTGTTCGTGCCGATCATCGGCCATGCGGGGCT CACGCTGAGCATCGGCGTGGGCGCGTGCCTGAACTCGCTGCTGCTCTTCATCGGGCTGCGCCGCCGCGGC ATCTATCAGCCGTCGTCCGGCTGGCTGCGCTTTTTCGCGCAGCTCGCGGGCGCCTCGCTCGTGCTCGCCG GCGTGATGCACTGGCTCGCGATCAACTTCGACTGGACCGCGATGCGCGCGGCGCCGCTCGAGCGGATCGC GCTGATGGCCGCCTGCCTCGTTCTGTTCGCTGCACTATATTTCGGTATGTTGTGGCTGATGGGTTTCAAA TACGCGTACTTCAGACGGCGCGCCAAGTA
Protein Sequence	>gi\|237811120\|ref\|YP_002895571.1\| integral membrane protein MviN [Burkholderia pseudomallei MSHR346] MRMTGSETGNYNNKIKRVASGSRIGRMPAPALARGPAGSRQRLVSGAPRAGAPMPVRAFCSNVSVAAARG PYNKRPMNLFRALLTVSGFTLLSRVTGLARETLIARAFGASQFTDAFYVAFRIPNLLRRLSAEGAFSQAF VPILAEFKNQKGHDATKALVDAMSTVLAWALALLSLAGIAGASWVVFAVASGLRTDGQAFPLAVAMTRIM FPYIVFISLTTLASGVLNTYKRFSLPAFAPVLLNVAFIVAAVFVAPHLKVPVYALAWAVIAGGALQFAVQ LPGLKKIDMMPAIGVNPLRALAHPGVKRVLAKMVPATFAVSVAQLSLIINTNIASRLGQGAVSWINYADR LMEFPTALLGVALGTILLPSLSKAHVDADSTEYSALLDWGLRVTFLLAAPSALALFFFAEPLTATLFNYG KFDAHTVTMVARALATYGIGLVGIILIKILAPGFYAKQDIKTPVKIAIGVLVVTQLSNYVFVPIIGHAGL TLSIGVGACLNSLLLFIGLRRRGIYQPSSGWLRFFAQLAGASLVLAGVMHWLAINFDWTAMRAAPLERIA LMAACLVLFAALYFGMLWLMGFKYAYFRRRAK
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: mviN mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells (Ling et al., 2006).
COG	COG0728R, under R: General function prediction only
References	*Ling et al., 2006:* Ling JM, Moore RA, Surette MG, Woods DE. The mviN homolog in Burkholderia pseudomallei is essential for viability and virulence. Canadian journal of microbiology. 2006; 52(9); 831-842. [PubMed: 17110975].


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mviN