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wcbC

Victor ID 2004
Gene Name wcbC
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3093048
NCBI Protein GI 53720416
Locus Tag BPSL2807
Genbank Accession BX571965
Protein Accession YP_109402
Other Database IDs UniProtKB-ID: Q7BMG8_BURPS
UniRef100: UniRef100_C4KUD0
UniRef90: UniRef90_C4KUD0
UniRef50: UniRef50_Q2SYX5
UniParc: UPI00000BEF66
EMBL: AF228583
EMBL: BX571965
EMBL-CDS: AAK49796.1
EMBL-CDS: CAH36817.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2807
HOGENOM: HBG400220
OMA: SKSATIP
ProtClustDB: CLSK917844
BioCyc: BPSE272560:BPSL2807-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3355329
Gene Ending Position 3356492
Gene Strand (Orientation) -
Protein Name putative capsular polysaccharide biosynthesis/export protein
Protein pI 8.79
Protein Weight 36740.41
Protein Length 387
Protein Note Also known as cpxDSimilar to Actinobacillus pleuropneumoniae capsular polysaccharide biosynthesis/export protein CpxD precursor SWALL:Q44132 (EMBL: U36397) (394 aa) fasta scores: E(): 6.4e-52, 41.19% id in 386 aa, Identical to Burkholderia mallei capsular polysaccharide biosynthesis/export protein WcbC SWALL:Q9AI48 (EMBL: AF285636) (387 aa) fasta scores: E(): 5.8e-141, 100% id in 387 aa
DNA Sequence 
>gi|53717639:3355329-3356492 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
ATCAGTACCTGACTGTCTGAACGCCGGTAATCACCGGATACGCAACGGAGAACACGACATTCAAGAATTT
TTGAAGTTCGGCAATCGGCGCATTCGAAACGTACAACAGATCGTTGTTGTCGACCCTGAAGCTCTGAGCC
ACGAAAAACGAATTCGGATCGCGAAGATTCACGCGATACACGACAGGCACCTTTCCGTCCGCAGTCGTAC
GCACGGGAGCCGTCGGCCATTTCAGCGCGTTGGCGTCTTCAAGTCGGAAGATGAATACGCCCTTTGCATC
GGCGCGCGAATCCTGCAAGCCGCCAGCACGCGCCAGGGCCTGCGCAAGCGTGATGCCCTTCGCTTCAAAA
TTGATTTCGTCATTCTTGCCCGTCGCGCCGAGCACCGTAAAGCTATACGGCTGAAACAGGACAGTGACCA
CGTCGCCCGCATGCAGCGGGACATTCTGCCGCGGATCACGAATAACCATGTCGAGCGGCAACGAGGCCAC
CGTCTTGCCGCGCGTTATCTGGATCGTAACCTTGTCAACCGGGTGCTTCGCCCCGCCTGCGCTCGCCAAT
GCATCAAGCAGGCGCTCGCCCCGAGCGGTCAGAGCCATGCGAGCGTTTTCCGCCACATCGCCCACGACCG
TCACATATGACGTCTCGTTGCGTGAAAGCTTCACGAGCACTTGCGGATCGTGCGCCATGCTCTTCAGCCG
CGCGGCAATCTCACGCGCCAACTGCGTGGGCGAGCGGCCGGCCGCCTTGACCTGGCCCGCAAACGGAATA
TTGACATTGCCGTCGCCATCGATGGCTTGATCGGGCAGCACCGTCACGCGCGCGTTCGCCGGCCCCGAAC
TCCCTTCCGACTGAGCCGCGCCAAAAAGCGTGGCGGGTGGCGCCTCCCAGATGGACACCTGAATCGTATC
GCCGACGCCCAACTGTTGCCGGAACGACGCACCGCCGCCCAGCGCCGTCACGAAGTCCGCCGTGTTTCGA
TCAGCAAACAGCTGGCGCGCGACATCCTCGGTCACATCGACGATCTGAATTCCGGATGGACTCTGCGCAG
CCCGCGCGATTTGCGCGCCACTGGCCCCCGACGTAGGGATACTTGAGCAACCGGCGAGCGTGACCGCGCC
CATGACACACGCGATCAAAAACGTTTTGCAGAATGGACGCGACA
Protein Sequence 
>gi|53720416|ref|YP_109402.1| putative capsular polysaccharide biosynthesis/export protein [Burkholderia pseudomallei K96243]
MSRPFCKTFLIACVMGAVTLAGCSSIPTSGASGAQIARAAQSPSGIQIVDVTEDVARQLFADRNTADFVT
ALGGGASFRQQLGVGDTIQVSIWEAPPATLFGAAQSEGSSGPANARVTVLPDQAIDGDGNVNIPFAGQVK
AAGRSPTQLAREIAARLKSMAHDPQVLVKLSRNETSYVTVVGDVAENARMALTARGERLLDALASAGGAK
HPVDKVTIQITRGKTVASLPLDMVIRDPRQNVPLHAGDVVTVLFQPYSFTVLGATGKNDEINFEAKGITL
AQALARAGGLQDSRADAKGVFIFRLEDANALKWPTAPVRTTADGKVPVVYRVNLRDPNSFFVAQSFRVDN
NDLLYVSNAPIAELQKFLNVVFSVAYPVITGVQTVRY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wcbC mutation is attenuated in mice (Reckseidler et al., 2001).
COG COG1596M, under M: Cell wall/membrane/envelope biogenesis
References
Reckseidler et al., 2001: Reckseidler SL, DeShazer D, Sokol PA, Woods DE. Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant. Infection and immunity. 2001; 69(1); 34-44. [PubMed: 11119486].