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sctU from Burkholderia pseudomallei 1710b

Victor ID 1972
Gene Name sctU from Burkholderia pseudomallei 1710b
Sequence Strain (Species/Organism) Burkholderia pseudomallei 1710b
NCBI Gene ID 3694226
NCBI Protein GI 76819722
Locus Tag BURPS1710b_A0680
Protein Accession YP_335839.1
Other Database IDs UniProtKB-ID: Q3JKR4_BURP1
UniRef100: UniRef100_Q3JKR4
UniRef90: UniRef90_Q3JKR4
UniRef50: UniRef50_A3P7C2
UniParc: UPI00005C38E8
EMBL: CP000125
EMBL-CDS: ABA53669.1
RefSeq_NT: NC_007435.1
GenomeReviews: CP000125_GR
KEGG: bpm:BURPS1710b_A0680
TIGR: BURPS1710b_A0680
eggNOG: COG1377
HOGENOM: HBG529770
OMA: PPRQRVG
ProtClustDB: PRK09108
Taxonomy ID 320372
Chromosome No II
Gene Starting Position 877759
Gene Ending Position 878958
Gene Strand (Orientation) -
Protein Name type III secretion system protein
DNA Sequence 
>gi|76817237:877759-878958 Burkholderia pseudomallei 1710b chromosome chromosome II, complete sequence
GTCATGACGACCTCGCGGAGGAAACGGCGGCGACCGCGCGCGCGCCCGAGAGGGACTCGACCCAGCGCAG
GATCGCGGCCACCGTCTCGAACAGCTCTTCGGGAATCGACGCGTCGCGCTCGACGCGGTACAGCGCGCGC
GCGACGCTCGGATTGCCGACGATCGGCACGCCGAGCGCGTGCGCGTGGCGGCGCAGCGCGAGCGCGCCGT
CGTCGACGGCCTTCTCGATGACCCGCGGCAGCGGATGCTCGTCGGGCGCATAGCGGATCGCGACCGCGTA
GTGCGTCGGGTTGACGACGAGCACGTTCGCCTGGCCGACCCGCTGCCGCGGCGGCGCGCTCGTCGCAATC
TCGCGCGCGAGCCGGCGGCGCTCGCCCTTCGTGTGCGGATCGCCGTCGCTCTCCTTGTGCTCGCGCTTGA
CTTCCTCCTTCGTCATCCGGTTCTCGCGAACGAACATCACGCGTGCGATCTTGTAATCGGCCGCCGCGAG
CACCGCGACGACGACCGACACGGTGCCGAGCAGCTTCATCAGCACCGTCCACAGCACGCGCGCGAGCTGC
GGCGTCGCTTCGTACACGCTCGCGACGACGAGCGGAAACAGCGAGGTCATCATCTTCCATGCCACGCACG
CGAGCACGAGCGCCTTGACGATCATCTTCACGAGCTCGAGCAGCGACTTCAGCGAGAAGATCCGCTTGAT
GCCCGCCATCGGATTGATCGCGTCGAACTTCGGCATCACGGGCTCGAGCGTGATCAGGAAGCCCGCCTGC
GGCGCCTGCGACACGATGCCCGCGACGATCGCGGCGGCGACGAACGGCAGCATCGTCAGCACGGCGCTCG
CGGCGAGATCGTGCAGCGCGGCGAGCGTCGCCTGCGGGGTGCGCTCGCCGCGCACGAAGTCGAGCGCGGT
GCGAACCGCGCGCGAGAGGCCGCCCGTGAGCATCGATTCGCACGCCGTGAGCACGCCGATCGCGGCCGCG
AGCGTCATCGCGTCGGCGATGTCCTTGCTCTTGGCGACCTGGCCCTTCTCGCGCACCTTCTTCAGCTTCT
TCTCGGTGGGCTCTTCGGTTTTCTCTTCGGCCATCGCCGCGTTTCCTTCGGGAGTCGGAGATGCCGCGTA
CGTTAGCGGCGCGCCGCGCGCCGCGCGCGCGCCGAGCCGAAGCCGCGCCGCCGGATGCGAAGCGCGCGCC
GTGCTTCGCA
Protein Sequence 
>gi|76819722|ref|YP_335839.1| type III secretion system protein HrcU [Burkholderia pseudomallei 1710b] MRSTARASHPAARLRLGARAARGAPLTYAASPTPEGNAAMAEEKTEEPTEKKLKKVREKGQVAKSKDIADAMTLAAAIGVLTACESMLTGGLSRAVRTALDFVRGERTPQATLAALHDLAASAVLTMLPFVAAAIVAGIVSQAPQAGFLITLEPVMPKFDAINPMAGIKRIFSLKSLLELVKMIVKALVLACVAWKMMTSLFPLVVASVYEATPQLARVLWTVLMKLLGTVSVVVAVLAAADYKIARVMFVRENRMTKEEVKREHKESDGDPHTKGERRRLAREIATSAPPRQRVGQANVLVVNPTHYAVAIRYAPDEHPLPRVIEKAVDDGALALRRHAHALGVPIVGNPSVARALYRVERDASIPEELFETVAAILRWVESLSGARAVAAVSSARSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sctU mutant is attenuated in mice (Warawa and Woods, 2005).
COG COG1377NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Warawa and Woods, 2005: Warawa J, Woods DE. Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model. FEMS microbiology letters. 2005; 242(1); 101-108. [PubMed: 15621426].