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bsaZ

Victor ID 1987
Gene Name bsaZ
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3096627
NCBI Protein GI 53722555
Locus Tag BPSS1534
Genbank Accession BX571966
Protein Accession YP_111540
Other Database IDs UniProtKB-ID: BSAZ_BURPS
UniRef100: UniRef100_Q63K32
UniRef90: UniRef90_A3MCG6
UniRef50: UniRef50_Q3JL20
UniParc: UPI000043BD20
EMBL: BX571966
EMBL-CDS: CAH39007.1
RefSeq_NT: NC_006351.1
GenomeReviews: BX571966_GR
KEGG: bps:BPSS1534
HOGENOM: HBG529770
OMA: QPNPGAY
ProtClustDB: PRK08156
BioCyc: BPSE272560:BPSS1534-MONOMER
Taxonomy ID 272560
Chromosome No 2
Gene Starting Position 2088081
Gene Ending Position 2089316
Gene Strand (Orientation) -
Protein Name surface presentation of antigens protein SpaS
Protein pI 8.59
Protein Weight 40787.54
Protein Length 411
Protein Note Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins
DNA Sequence 
>gi|53721039:2088081-2089316 Burkholderia pseudomallei K96243 chromosome 2, complete sequence
GTCAAGCGTTTTGATCGCCCGTTCGGGCCGGCGCGCCGCCGTCCGGCGCCGGGCCGTCCGGCGAACCGGC
GTTCGGCGCAGCGGCGCCCGGTGGGGCGTCGTCGGGAAAGGCGTTGTCCGCGCAGGCGTCGCCCGGCGGG
GCCACGCCGTCGCGCGCTTGCGGCTCGGCCGAAGTCGGCGCGCGCGTCTCGGGCGGCGGCCCGCCGCGAT
TGGCCGCCTCGACCTCGCCGAGCCAGATCAGCACGCGCATCACGCCGTCGATGTCGTCGTGGCTCACGAA
GCTGTAGCGGCGCGGCGAGTTGCGATAGATCGAGCGCGCGAGCGCGACGTTGCGCACGACGGGCACGCCG
CACGCTTCGGCATGCCGAATGACGGCGAGCGCGCGTGCGTTGGTCTCGCGCACCGACACGAACGGAATCG
GCACGATGTCCGGATTCACGTAGACGCCGATCGCGATGTGGGTCGGGTTCGCGACGATGAAATCGGACTG
CTCGACGTTCGCCTTGATCTCCTCCGACAGCAGTTCCTGATGAATCTCGCGCCGCTTGCTCTTGATCTCG
TGATTGCCCTCGCTCTCCTTGTATTCCTGCTTCACCTCGTGCTTGTCCATCTTCAGTTCGCGGTGGTACA
GGAAGTATTCGACGGCGGCGTCGAGGATCAGCACGGGCAGTGCGCACAGCAGGAACAGCAGCACGAGGCG
CACCGTGAGCACGATCCACATGTGGCCGAGCAGCGCCGGACGCGCGCGGAACAGCCCGAACACGTCGGCG
TGGTAGAGATCGGCGAACACGCGCACCGTGAGCGCGAACACGCCGACATAGAGCAGCGCCTTCACCGCGT
CCTTCGCCGAGCGCCAGCTGAAGAGCCGCTTCATTCCCTTGACCGGGTCGAGCGCGGTGAGATCGAAGCG
GATCGATTCGACCGCGAGCGTGAAGCGGCTTTGCACAAGCGACGGCAGCGCGCCCGCCGCCGCGCAGAGC
AGCACGAACGGCGCGGCGATGCGCAGGAACAGCTTCGCCCACGCGAATGCGTACGCACCCGGGTTCGGCT
GCGCGCCCGTCGACGCGATCCGCACGAATTCGGCCGCGATGCGCGTCAGATCGACGAGCGCGGGCGCGGC
CAGCGCGCCCGTGGCGATCACGATGAGCGCGACGATGTCCCGCGCCTTGAACGTCTGCCCCTTCTTCGCC
GCGTCGCGCAGCTTCTTCGCGGTCGGCTTCTCGGTTTTCTCGGCCA
Protein Sequence 
>gi|53722555|ref|YP_111540.1| surface presentation of antigens protein SpaS [Burkholderia pseudomallei K96243]
MAEKTEKPTAKKLRDAAKKGQTFKARDIVALIVIATGALAAPALVDLTRIAAEFVRIASTGAQPNPGAYA
FAWAKLFLRIAAPFVLLCAAAGALPSLVQSRFTLAVESIRFDLTALDPVKGMKRLFSWRSAKDAVKALLY
VGVFALTVRVFADLYHADVFGLFRARPALLGHMWIVLTVRLVLLFLLCALPVLILDAAVEYFLYHRELKM
DKHEVKQEYKESEGNHEIKSKRREIHQELLSEEIKANVEQSDFIVANPTHIAIGVYVNPDIVPIPFVSVR
ETNARALAVIRHAEACGVPVVRNVALARSIYRNSPRRYSFVSHDDIDGVMRVLIWLGEVEAANRGGPPPE
TRAPTSAEPQARDGVAPPGDACADNAFPDDAPPGAAAPNAGSPDGPAPDGGAPARTGDQNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bsaZ mutant is attenuated in mouse macrophages (Stevens et al., 2002).
COG COG1377NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Stevens et al., 2002: Stevens MP, Wood MW, Taylor LA, Monaghan P, Hawes P, Jones PW, Wallis TS, Galyov EE. An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Molecular microbiology. 2002; 46(3); 649-659. [PubMed: 12410823].