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wcbB

Victor ID 2003
Gene Name wcbB
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3093047
NCBI Protein GI 53720417
Locus Tag BPSL2808
Genbank Accession BX571965
Protein Accession YP_109403
Other Database IDs UniProtKB-ID: Q63R65_BURPS
UniRef100: UniRef100_Q63R65
UniRef90: UniRef90_Q3JP30
UniRef50: UniRef50_A0K4U6
UniParc: UPI000043B4FA
EMBL: BX571965
EMBL-CDS: CAH36818.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2808
NMPDR: fig|272560.3.peg.5489
HOGENOM: HBG335043
OMA: IFNTSFQ
ProtClustDB: CLSK710592
BioCyc: BPSE272560:BPSL2808-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3356673
Gene Ending Position 3357824
Gene Strand (Orientation) +
Protein Name putative capsular polysaccharide glycosyltransferase biosynthesis protein
Protein pI 7.74
Protein Weight 40869.76
Protein Length 383
Protein Note Similar to Pseudomonas aeruginosa glycosyltransferase WbpX or pa5449 SWALL:O84908 (EMBL: AF010181) (460 aa) fasta scores: E(): 2.3e-16, 33.33% id in 267 aa, and to previously sequenced Burkholderia pseudomallei putative glycosyltransferase WcbB SWALL:Q93UK1 (EMBL: AF228583) (365 aa) fasta scores: E(): 7e-147, 98.88% id in 357 aa, and to Burkholderia mallei putative glycosyltransferase WcbB SWALL:Q9AI49 (EMBL: AF285636) (280 aa) fasta scores: E(): 2.8e-116, 99.64% id in 280 aa, and to Burkholderia thailandensis putative glycosyltransferase WcbB SWALL:Q9AI57 (EMBL: AF285634) (280 aa) fasta scores: E(): 1.2e-84, 72.76% id in 279 aa
DNA Sequence 
>gi|53717639:3356673-3357824 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
CTTGTCAATCATCTACCTAGACGTCACGCGTCTCGTGACCCGCCTTTACCAGGGTCTACTGCCGACGGGA
GTGGACCGCGTCGGGCTGCAGTACATCCGGCACTATGGCAGCCGAGCGCGCGCCGTGCTCAGCGAGCGTG
GCTTTTTCGCCATTCTGTCGGAAAGAGATTCGGCTCTTGTTTTCGCGTGGCTTACGTCATCAATTGGTAA
CAAAAATGCGATATTCAGGCTAGCCGCGCATGCTTGCCTGAGATCGATATTCAACACAAGTTTCCAAAAT
GGCATATTGTTGCATACAAGCCACAGCGGAATGGAATTTCCACGCTATTACAAGAAACTGGCGAGCCTCG
GTATTAAGTCGGTATTCCTCATCCACGACCTCATCCCGCTGACTCATGCCGAATACACCCGCCCGGGAGT
CGAGCACACGCATCGCCGGCGAATTCATACGGCGTTAGGGTACGCCAGCGGCCTCATCGCCAATTCCCGA
TCGACGCTGGAATCGCTCGCGGCGGAAGCGACCCGCGCCGCGCTGCCGCTGCCGCCATGCGCAATCGCGC
ACCTCGCTTCGGGCGTTGAGCCGCAGCCGCCCCGCCAGCGCCTGCTTGATGCCCCCTACTTCGTAATGCT
GGGCACCATCGAGCCGCGCAAAAATCACTGGTTCATCCTGCATGTCTGGCGGCGTCTGATCGAACAACTC
GGGAACGCCGCGCCGAAGCTGGTCGTGATCGGGCGTCGAGGCTGGGAATGCGAGAACGTCATCGACATGC
TGGAACGTTGCGCAAGCCTGCCGGGCACGGTGATCGAAGAGGCCAACTGCTCCGACGAACGCCTTCACGC
CTGGTTGCAGCATGCGCGCGCCCTTCTCTTTCCTTCGTTCGTCGAGGGTTACGGGATGCCGCTTGTCGAA
GCACTGGGGCTCGGCGTACCCGTCCTTGCAAGCGACCTGGACGTGTTCCGCGAAGTCGCGGCGGACATCC
CCGATTACCTCGATCCGCTCGACGGCCCGGCGTGGGCTGCCCGCATCCGTGACTACGCTCGGGACGACAG
CCACGAACGCACCGCGCAACTCGCCCGAATCGAACACTTCCGCGAACCGACGTGGGTCGACCATTTCGAA
CGCGTCGATGCCTTTCTTGACACGCTGCGCTA
Protein Sequence 
>gi|53720417|ref|YP_109403.1| putative capsular polysaccharide glycosyltransferase biosynthesis protein [Burkholderia pseudomallei K96243]
MSIIYLDVTRLVTRLYQGLLPTGVDRVGLQYIRHYGSRARAVLSERGFFAILSERDSALVFAWLTSSIGN
KNAIFRLAAHACLRSIFNTSFQNGILLHTSHSGMEFPRYYKKLASLGIKSVFLIHDLIPLTHAEYTRPGV
EHTHRRRIHTALGYASGLIANSRSTLESLAAEATRAALPLPPCAIAHLASGVEPQPPRQRLLDAPYFVML
GTIEPRKNHWFILHVWRRLIEQLGNAAPKLVVIGRRGWECENVIDMLERCASLPGTVIEEANCSDERLHA
WLQHARALLFPSFVEGYGMPLVEALGLGVPVLASDLDVFREVAADIPDYLDPLDGPAWAARIRDYARDDS
HERTAQLARIEHFREPTWVDHFERVDAFLDTLR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wcbB mutant is attenuated in mice (Cuccui et al., 2007).
COG COG0438M, under M: Cell wall/membrane/envelope biogenesis
References
Cuccui et al., 2007: Cuccui J, Easton A, Chu KK, Bancroft GJ, Oyston PC, Titball RW, Wren BW. Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. Infection and immunity. 2007; 75(3); 1186-1195. [PubMed: 17189432].